Protein: PIP
Prolactin-inducible protein (Gross cystic disease fluid protein 15) (GCDFP-15) (Prolactin-induced protein) (Secretory actin-binding protein) (SABP) (gp17)

Gene: PIP
Organism: Homo sapiens
Interactions: 193
UniProt ID: P12273

Gene Ontology (top 5):
GO:0001580 - detection of chemical stimulus involved in sensory perception of bitter taste
GO:0002682 - regulation of immune system process
GO:0003779 - actin binding
GO:0004190 - aspartic-type endopeptidase activity
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

345803

MYC
Myc proto-oncogene protein

3

1

High-throughput

0.640

High

519090

DDX31
ATP-dependent DNA helicase DDX31

2

1

High-throughput

0.628

High

518995

CHD4
Chromodomain-helicase-DNA-binding protein 4

2

1

High-throughput

0.611

High

151963

TOR1A
Torsin-1A

2

0

High-throughput

0.594

High

318563

EYA4
Eyes absent homolog 4

1

1

High-throughput

0.536

High

518978

NFKB2
Nuclear factor NF-kappa-B p100 subunit

1

2

High-throughput

0.536

High

518980

TF65
Transcription factor p65

1

3

High-throughput

0.536

High

518982

UBE3A
Ubiquitin-protein ligase E3A

1

1

High-throughput

0.536

High

518983

FAK1
Focal adhesion kinase 1

1

1

High-throughput

0.536

High

518984

RING1
E3 ubiquitin-protein ligase RING1

1

2

High-throughput

0.536

High

518986

NFAC3
Nuclear factor of activated T-cells, cytoplasmic 3

1

3

High-throughput

0.536

High

518988

STRN3
Striatin-3

1

1

High-throughput

0.536

High

518989

TOP3A
DNA topoisomerase 3-alpha

1

1

High-throughput

0.536

High

518994

KANK1
KN motif and ankyrin repeat domain-containing protein 1

1

2

High-throughput

0.536

High

519018

BCOR
BCL-6 corepressor

1

1

High-throughput

0.536

High

519054

ZBT8A
Zinc finger and BTB domain-containing protein 8A

1

1

High-throughput

0.536

High

519059

ZBT10
Zinc finger and BTB domain-containing protein 10

1

1

High-throughput

0.536

High

519061

GWL
Serine/threonine-protein kinase greatwall

1

1

High-throughput

0.536

High

519068

RING2
E3 ubiquitin-protein ligase RING2

1

2

High-throughput

0.536

High

519069

EYA1
Eyes absent homolog 1

1

1

High-throughput

0.536

High

519072

PCGF1
Polycomb group RING finger protein 1

1

2

High-throughput

0.536

High

519079

RHG39
Rho GTPase-activating protein 39

1

1

High-throughput

0.536

High

519088

TDRD3
Tudor domain-containing protein 3

1

1

High-throughput

0.536

High

519091

RMI1
RecQ-mediated genome instability protein 1

1

1

High-throughput

0.536

High

519044

ARH40
Rho guanine nucleotide exchange factor 40

2

1

High-throughput

0.521

High

519104

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

1

1

High-throughput

0.515

High

47745

RBM47
RNA-binding protein 47

1

0

High-throughput

0.513

High

204280

MS18B
Protein Mis18-beta

1

0

High-throughput

0.513

High

239033

CTND1
Catenin delta-1

1

0

High-throughput

0.513

High

257158

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

1

0

High-throughput

0.513

High

278991

RAD17
Cell cycle checkpoint protein RAD17

1

0

High-throughput

0.513

High

318919

CEP43
Centrosomal protein 43

1

0

High-throughput

0.513

High

385997

P53
Cellular tumor antigen p53

1

0

High-throughput

0.513

High

518956

HXB9
Homeobox protein Hox-B9

1

0

High-throughput

0.513

High

518957

CSK22
Casein kinase II subunit alpha'

1

0

High-throughput

0.513

High

518966

CDN1B
Cyclin-dependent kinase inhibitor 1B

1

0

High-throughput

0.513

High

518972

SMTN
Smoothelin

1

0

High-throughput

0.513

High

518990

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

0

High-throughput

0.513

High

518998

CND1
Condensin complex subunit 1

1

0

High-throughput

0.513

High

519000

PMVK
Phosphomevalonate kinase

1

0

High-throughput

0.513

High

519001

INF2
Inverted formin-2

1

0

High-throughput

0.513

High

519002

QRIC1
Transcriptional regulator QRICH1

1

0

High-throughput

0.513

High

519003

GRDN
Girdin

1

0

High-throughput

0.513

High

519006

CRTC2
CREB-regulated transcription coactivator 2

1

0

High-throughput

0.513

High

519009

UBAP2
Ubiquitin-associated protein 2

1

0

High-throughput

0.513

High

519010

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

1

0

High-throughput

0.513

High

519011

STRP1
Striatin-interacting protein 1

1

0

High-throughput

0.513

High

519012

CE350
Centrosome-associated protein 350

1

0

High-throughput

0.513

High

519013

RN220
E3 ubiquitin-protein ligase RNF220

1

0

High-throughput

0.513

High

519016

ANR54
Ankyrin repeat domain-containing protein 54

1

0

High-throughput

0.513

High

519017

CDC73
Parafibromin

1

0

High-throughput

0.513

High

519023

NPHP3
Nephrocystin-3

1

0

High-throughput

0.513

High

519024

KAISO
Transcriptional regulator Kaiso

1

0

High-throughput

0.513

High

519029

ZGRF1
5'-3' DNA helicase ZGRF1

1

0

High-throughput

0.513

High

519030

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

0

High-throughput

0.513

High

519034

KMT2E
Inactive histone-lysine N-methyltransferase 2E

1

0

High-throughput

0.513

High

519039

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.513

High

519042

MIPO1
Mirror-image polydactyly gene 1 protein

1

0

High-throughput

0.513

High

519043

CCHCR
Coiled-coil alpha-helical rod protein 1

1

0

High-throughput

0.513

High

519046

ITLN2
Intelectin-2

1

0

High-throughput

0.513

High

519050

N42L2
NEDD4-binding protein 2-like 2

1

0

High-throughput

0.513

High

519052

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.513

High

519058

ESS2
Splicing factor ESS-2 homolog

1

0

High-throughput

0.513

High

519060

IP3KC
Inositol-trisphosphate 3-kinase C

1

0

High-throughput

0.513

High

519062

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

0

High-throughput

0.513

High

519063

LMLN
Leishmanolysin-like peptidase

1

0

High-throughput

0.513

High

519070

CTIP
DNA endonuclease RBBP8

1

0

High-throughput

0.513

High

519071

CND3
Condensin complex subunit 3

1

0

High-throughput

0.513

High

519073

CDK19
Cyclin-dependent kinase 19

1

0

High-throughput

0.513

High

519085

ADNP
Activity-dependent neuroprotector homeobox protein

1

0

High-throughput

0.513

High

519089

AUNIP
Aurora kinase A- and ninein-interacting protein

1

0

High-throughput

0.513

High

519106

ANGE1
Protein angel homolog 1

1

0

High-throughput

0.513

High

519107

POLH
DNA polymerase eta

1

0

High-throughput

0.513

High

519111

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.513

High

519014

USPL1
SUMO-specific isopeptidase USPL1

1

0

High-throughput

0.493

High

518969

DYN2
Dynamin-2

1

0

High-throughput

0.493

High

64787

TBKB1
TANK-binding kinase 1-binding protein 1

1

1

High-throughput

0.489

High

519022

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

1

High-throughput

0.489

High

519037

NIN
Ninein

1

1

High-throughput

0.489

High

519075

SCAPE
S phase cyclin A-associated protein in the endoplasmic reticulum

1

1

High-throughput

0.489

High

519087

AZI2
5-azacytidine-induced protein 2

1

1

High-throughput

0.489

High

519097

STRN4
Striatin-4

1

1

High-throughput

0.489

High

519103

TBK1
Serine/threonine-protein kinase TBK1

1

1

High-throughput

0.489

High

519051

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

High-throughput

0.480

High

170232

TIF1A
Transcription intermediary factor 1-alpha

1

1

Small-scale

0.479

High

378962

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

518960

PML
Protein PML

1

1

High-throughput

0.479

High

518961

MCM5
DNA replication licensing factor MCM5

1

1

High-throughput

0.479

High

518967

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.479

High

518970

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

2

High-throughput

0.479

High

518976

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

518985

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

1

High-throughput

0.479

High

518991

DX39B
Spliceosome RNA helicase DDX39B

1

1

High-throughput

0.479

High

519049

REQU
Zinc finger protein ubi-d4

1

3

High-throughput

0.479

High

519101

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

519109

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

2

Small-scale

0.479

High

116963

SGK1
Serine/threonine-protein kinase Sgk1

1

0

High-throughput

0.458

High

125124

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

Small-scale

0.458

High

133859

DDX3X
ATP-dependent RNA helicase DDX3X

1

0

Small-scale

0.458

High

226382

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

324200

BAG3
BAG family molecular chaperone regulator 3

1

0

Small-scale

0.458

High

373609

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

416343

S10A9
Protein S100-A9

1

0

High-throughput

0.458

High

518952

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

518953

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.458

High

518954

HIS3
Histatin-3

1

0

Small-scale

0.458

High

518955

TFE2
Transcription factor E2-alpha

1

0

High-throughput

0.458

High

518959

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

518964

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

518974

LYSC
Lysozyme C

1

0

High-throughput

0.458

High

518977

VIGLN
Vigilin

1

0

High-throughput

0.458

High

519004

LARP7
La-related protein 7

1

0

High-throughput

0.458

High

519019

SOSD1
Sclerostin domain-containing protein 1

1

0

Small-scale

0.458

High

519031

PHF6
PHD finger protein 6

1

0

Small-scale

0.458

High

519055

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

519074

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

519076

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

519078

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

519082

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

519095

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

519096

ANLN
Anillin

1

0

High-throughput

0.458

High

519105

TCAL9
Transcription elongation factor A protein-like 9

1

0

High-throughput

0.458

High

519112

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.458

High

518958

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

2

High-throughput

0.445

High

518999

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.437

High

519080

DDX24
ATP-dependent RNA helicase DDX24

1

1

High-throughput

0.437

High

519108

NINL
Ninein-like protein

1

1

High-throughput

0.437

High

401326

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

518963

FUS
RNA-binding protein FUS

1

0

High-throughput

0.426

High

519007

ODFP2
Outer dense fiber protein 2

1

0

High-throughput

0.426

High

519026

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

0

High-throughput

0.426

High

519048

ESR2
Estrogen receptor beta

1

0

High-throughput

0.426

High

519066

CK5P2
CDK5 regulatory subunit-associated protein 2

1

0

High-throughput

0.426

High

519015

CP135
Centrosomal protein of 135 kDa

1

1

High-throughput

0.407

High

519064

CEP63
Centrosomal protein of 63 kDa

1

1

High-throughput

0.407

High

129460

MANBA
Beta-mannosidase

1

0

High-throughput

0.279

Low

196395

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

0

High-throughput

0.279

Low

237157

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

0

High-throughput

0.279

Low

296789

NOL4
Nucleolar protein 4

1

0

High-throughput

0.279

Low

296836

KBTBB
Kelch repeat and BTB domain-containing protein 11

1

0

High-throughput

0.279

Low

299233

FARP2
FERM, ARHGEF and pleckstrin domain-containing protein 2

1

0

High-throughput

0.279

Low

518965

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

0

High-throughput

0.279

Low

518968

RBP2
E3 SUMO-protein ligase RanBP2

1

0

High-throughput

0.279

Low

518971

AGFG1
Arf-GAP domain and FG repeat-containing protein 1

1

0

High-throughput

0.279

Low

518973

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

0

High-throughput

0.279

Low

518975

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

1

0

High-throughput

0.279

Low

518987

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

0

High-throughput

0.279

Low

518996

SLMAP
Sarcolemmal membrane-associated protein

1

0

High-throughput

0.279

Low

518997

CND2
Condensin complex subunit 2

1

0

High-throughput

0.279

Low

519005

IQCC
IQ domain-containing protein C

1

0

High-throughput

0.279

Low

519020

GGYF2
GRB10-interacting GYF protein 2

1

0

High-throughput

0.279

Low

519021

AEBP2
Zinc finger protein AEBP2

1

0

High-throughput

0.279

Low

519028

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

0

High-throughput

0.279

Low

519033

M21D2
Nucleotidyltransferase MB21D2

1

0

High-throughput

0.279

Low

519035

RBFA
Putative ribosome-binding factor A, mitochondrial

1

0

High-throughput

0.279

Low

519036

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.279

Low

519041

CEP76
Centrosomal protein of 76 kDa

1

0

High-throughput

0.279

Low

519045

DI3L1
DIS3-like exonuclease 1

1

0

High-throughput

0.279

Low

519047

K0232
Uncharacterized protein KIAA0232

1

0

High-throughput

0.279

Low

519053

P2R3C
Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma

1

0

High-throughput

0.279

Low

519056

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.279

Low

519057

REPS1
RalBP1-associated Eps domain-containing protein 1

1

0

High-throughput

0.279

Low

519065

ALPK1
Alpha-protein kinase 1

1

0

High-throughput

0.279

Low

519067

SEBP2
Selenocysteine insertion sequence-binding protein 2

1

0

High-throughput

0.279

Low

519077

YTHD1
YTH domain-containing family protein 1

1

0

High-throughput

0.279

Low

519081

MFR1L
Mitochondrial fission regulator 1-like

1

0

High-throughput

0.279

Low

519084

VP33B
Vacuolar protein sorting-associated protein 33B

1

0

High-throughput

0.279

Low

519086

WDCP
WD repeat and coiled-coil-containing protein

1

0

High-throughput

0.279

Low

519092

SPE39
Spermatogenesis-defective protein 39 homolog

1

0

High-throughput

0.279

Low

519093

TAF9B
Transcription initiation factor TFIID subunit 9B

1

0

High-throughput

0.279

Low

519094

ZDBF2
DBF4-type zinc finger-containing protein 2

1

0

High-throughput

0.279

Low

519099

CT2NL
CTTNBP2 N-terminal-like protein

1

0

High-throughput

0.279

Low

519100

FA8A1
Protein FAM8A1

1

0

High-throughput

0.279

Low

519102

SUN2
SUN domain-containing protein 2

1

0

High-throughput

0.279

Low

519110

PHOCN
MOB-like protein phocein

1

0

High-throughput

0.279

Low

353252

CD4
T-cell surface glycoprotein CD4

1

0

Small-scale

0.261

Low

301577

TRI37
E3 ubiquitin-protein ligase TRIM37

1

0

High-throughput

0.249

Low

518962

GRK5
G protein-coupled receptor kinase 5

1

0

High-throughput

0.249

Low

518981

K1C17
Keratin, type I cytoskeletal 17

1

0

High-throughput

0.249

Low

518993

RBM39
RNA-binding protein 39

1

0

High-throughput

0.249

Low

519025

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.249

Low

519027

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.249

Low

519032

SLX4
Structure-specific endonuclease subunit SLX4

1

0

Small-scale

0.249

Low

519040

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.249

Low

519098

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low

519113

M4K5
Mitogen-activated protein kinase kinase kinase kinase 5

1

0

High-throughput

0.249

Low

910

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low

200486

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.232

Low

518979

TAGL
Transgelin

1

0

High-throughput

0.232

Low

518992

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.232

Low

519008

CE170
Centrosomal protein of 170 kDa

1

0

High-throughput

0.232

Low

519038

POC5
Centrosomal protein POC5

1

0

High-throughput

0.232

Low

519083

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024