HitPredict

Interactor 1: CDK14 (O94921)
Cyclin-dependent kinase 14 (EC 2.7.11.22) (Cell division protein kinase 14) (Serine/threonine-protein kinase PFTAIRE-1) (hPFTAIRE1)
Gene: CDK14

Interactor 2: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.644

Property	Details
Experiments	16775625, 36931259
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 469 Hs			1 255
+	Hs
		625306 CDK2_HUMAN (132-429): 1.34e-141: 409: 50.67		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909447 CDK3_HUMAN (132-442): 4.46e-138: 400: 50.48		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909449 CDK17_HUMAN (5-466): 3.99e-131: 391: 43.75		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909472 CDK18_HUMAN (3-466): 7.76e-132: 391: 45.69		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		909448 CDK16_HUMAN (18-457): 3.87e-130: 387: 46.14		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		841132 CDK7_HUMAN (129-467): 2.78e-128: 377: 37.61		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Dm
		955011 Q94888_DROME (11-452): 3.82e-130: 388: 48.87		1433E_DROME (1-254): 2.95e-146: 411: 82.69
+	Dm
		955007 Q7KM03_DROME (50-452): 1.55e-129: 386: 55.31		1433E_DROME (1-254): 2.95e-146: 411: 82.69
+	Sc
		565487 PHO85_YEAST (129-422): 1.67e-128: 376: 51.16		BMH1_YEAST (2-243): 2.43e-134: 381: 75.72