Protein: OTX1
Homeobox protein OTX1 (Orthodenticle homolog 1)

Gene: OTX1
Organism: Homo sapiens
Interactions: 162
UniProt ID: P32242

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

686508

MDFI
MyoD family inhibitor

6

2

High-throughput

0.738

High

283166

RGS20
Regulator of G-protein signaling 20

5

3

High-throughput

0.720

High

686503

RBPMS
RNA-binding protein with multiple splicing

3

2

High-throughput

0.688

High

686539

RGS17
Regulator of G-protein signaling 17

3

2

High-throughput

0.675

High

660406

GRN
Progranulin

5

1

High-throughput

0.662

High

686509

KR412
Keratin-associated protein 4-12

4

20

High-throughput

0.644

High

208099

SPY2
Protein sprouty homolog 2

2

2

High-throughput

0.640

High

686437

KRT81
Keratin, type II cuticular Hb1

4

5

High-throughput

0.639

High

686413

COMP
Cartilage oligomeric matrix protein

4

5

High-throughput

0.637

High

686522

KRA32
Keratin-associated protein 3-2

4

3

High-throughput

0.637

High

686412

HXA1
Homeobox protein Hox-A1

1

20

High-throughput

0.621

High

686424

KR109
Keratin-associated protein 10-9

3

20

High-throughput

0.619

High

686467

LCE1B
Late cornified envelope protein 1B

3

1

High-throughput

0.617

High

642017

KRA59
Keratin-associated protein 5-9

3

20

High-throughput

0.616

High

686416

KR122
Keratin-associated protein 12-2

3

20

High-throughput

0.616

High

686423

KR108
Keratin-associated protein 10-8

3

20

High-throughput

0.616

High

686514

KRA92
Keratin-associated protein 9-2

3

20

High-throughput

0.616

High

686515

KR411
Keratin-associated protein 4-11

3

20

High-throughput

0.616

High

686521

KRA33
Keratin-associated protein 3-3

3

3

High-throughput

0.616

High

70754

VWC2L
von Willebrand factor C domain-containing protein 2-like

3

7

High-throughput

0.613

High

686475

TENS2
Tensin-2

3

1

High-throughput

0.613

High

686492

KRA13
Keratin-associated protein 1-3

3

20

High-throughput

0.613

High

686525

KRA15
Keratin-associated protein 1-5

3

20

High-throughput

0.613

High

70969

ZBT42
Zinc finger and BTB domain-containing protein 42

2

7

High-throughput

0.606

High

686433

ARI5A
AT-rich interactive domain-containing protein 5A

2

20

High-throughput

0.606

High

686440

TRIP6
Thyroid receptor-interacting protein 6

2

3

High-throughput

0.606

High

686463

UBAP2
Ubiquitin-associated protein 2

2

18

High-throughput

0.606

High

686473

FHL5
Four and a half LIM domains protein 5

2

6

High-throughput

0.606

High

686543

ZN330
Zinc finger protein 330

2

1

High-throughput

0.606

High

686483

ATL4
ADAMTS-like protein 4

3

1

High-throughput

0.604

High

686472

LCE2D
Late cornified envelope protein 2D

2

2

High-throughput

0.583

High

686443

OBF1
POU domain class 2-associating factor 1

2

0

High-throughput

0.580

High

686446

NDUF6
NADH dehydrogenase

2

0

High-throughput

0.580

High

686468

INT11
Integrator complex subunit 11

2

0

High-throughput

0.580

High

686482

GASP3
G protein-coupled receptor associated sorting protein 3

2

0

High-throughput

0.580

High

686501

PCSK5
Proprotein convertase subtilisin/kexin type 5

2

0

High-throughput

0.580

High

686504

SMIP9
Protein SPMIP9

2

0

High-throughput

0.580

High

686536

WWOX
WW domain-containing oxidoreductase

2

0

High-throughput

0.580

High

686520

KRA42
Keratin-associated protein 4-2

2

20

High-throughput

0.578

High

208325

SPY1
Protein sprouty homolog 1

2

2

High-throughput

0.573

High

686502

SMRC1
SWI/SNF complex subunit SMARCC1

1

20

High-throughput

0.573

High

686421

KR105
Keratin-associated protein 10-5

2

20

High-throughput

0.558

High

686425

KR10B
Keratin-associated protein 10-11

2

20

High-throughput

0.558

High

49940

F168B
Myelin-associated neurite-outgrowth inhibitor

2

2

High-throughput

0.553

High

66999

CRTP1
Cysteine-rich tail protein 1

2

1

High-throughput

0.553

High

180686

PA2GX
Group 10 secretory phospholipase A2

2

1

High-throughput

0.553

High

280858

KRT37
Keratin, type I cuticular Ha7

2

12

High-throughput

0.553

High

312821

CCN4
CCN family member 4

2

1

High-throughput

0.553

High

327958

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

2

5

High-throughput

0.553

High

474653

NHLC4
NHL-repeat-containing protein 4

2

1

High-throughput

0.553

High

650066

CO8A1
Collagen alpha-1(VIII) chain

2

4

High-throughput

0.553

High

686414

RGS19
Regulator of G-protein signaling 19

2

3

High-throughput

0.553

High

686415

KR121
Keratin-associated protein 12-1

2

2

High-throughput

0.553

High

686417

KR123
Keratin-associated protein 12-3

2

2

High-throughput

0.553

High

686422

KR107
Keratin-associated protein 10-7

2

20

High-throughput

0.553

High

686430

KRT85
Keratin, type II cuticular Hb5

2

5

High-throughput

0.553

High

686431

FBLN2
Fibulin-2

2

5

High-throughput

0.553

High

686434

KRA11
Keratin-associated protein 1-1

2

20

High-throughput

0.553

High

686438

LASP1
LIM and SH3 domain protein 1

2

5

High-throughput

0.553

High

686439

K1H1
Keratin, type I cuticular Ha1

2

12

High-throughput

0.553

High

686442

S15A2
Solute carrier family 15 member 2

2

1

High-throughput

0.553

High

686444

VWC2
Brorin

2

8

High-throughput

0.553

High

686448

KRA61
Keratin-associated protein 6-1

2

1

High-throughput

0.553

High

686449

KRA62
Keratin-associated protein 6-2

2

2

High-throughput

0.553

High

686454

KR133
Keratin-associated protein 13-3

2

5

High-throughput

0.553

High

686455

KR197
Keratin-associated protein 19-7

2

2

High-throughput

0.553

High

686457

KR132
Keratin-associated protein 13-2

2

5

High-throughput

0.553

High

686458

KLH26
Kelch-like protein 26

2

2

High-throughput

0.553

High

686461

CJ055
Uncharacterized protein C10orf55

2

1

High-throughput

0.553

High

686465

LCE1C
Late cornified envelope protein 1C

2

1

High-throughput

0.553

High

686471

LCE2C
Late cornified envelope protein 2C

2

2

High-throughput

0.553

High

686477

KR511
Keratin-associated protein 5-11

2

20

High-throughput

0.553

High

686479

KRA54
Keratin-associated protein 5-4

2

20

High-throughput

0.553

High

686480

KRA53
Keratin-associated protein 5-3

2

20

High-throughput

0.553

High

686484

CRDL2
Chordin-like protein 2

2

3

High-throughput

0.553

High

686485

UBP54
Inactive ubiquitin carboxyl-terminal hydrolase 54

2

2

High-throughput

0.553

High

686491

KRA71
Keratin-associated protein 7-1

2

1

High-throughput

0.553

High

686493

TRI42
Tripartite motif-containing protein 42

2

16

High-throughput

0.553

High

686496

M1AP
Meiosis 1 arrest protein

2

2

High-throughput

0.553

High

686500

KRT35
Keratin, type I cuticular Ha5

2

12

High-throughput

0.553

High

686511

KRA98
Keratin-associated protein 9-8

2

20

High-throughput

0.553

High

686513

KRA93
Keratin-associated protein 9-3

2

20

High-throughput

0.553

High

686516

KRA41
Keratin-associated protein 4-1

2

20

High-throughput

0.553

High

686518

KRA45
Keratin-associated protein 4-5

2

20

High-throughput

0.553

High

686519

KRA44
Keratin-associated protein 4-4

2

20

High-throughput

0.553

High

686523

KRA31
Keratin-associated protein 3-1

2

3

High-throughput

0.553

High

686528

SPY4
Protein sprouty homolog 4

2

2

High-throughput

0.553

High

686531

CFA68
Cilia- and flagella-associated protein 68

2

1

High-throughput

0.553

High

686532

NECT3
Nectin-3

2

2

High-throughput

0.553

High

686533

PLS2
Phospholipid scramblase 2

2

4

High-throughput

0.553

High

686534

ANR10
Ankyrin repeat domain-containing protein 10

2

14

High-throughput

0.553

High

686541

PP13
Galactoside-binding soluble lectin 13

2

1

High-throughput

0.553

High

686419

KR101
Keratin-associated protein 10-1

2

20

High-throughput

0.533

High

686470

LCE2A
Late cornified envelope protein 2A

1

1

High-throughput

0.523

High

686481

KR261
Keratin-associated protein 26-1

1

1

High-throughput

0.523

High

686512

KRA94
Keratin-associated protein 9-4

1

20

High-throughput

0.523

High

686530

CHRD
Chordin

1

8

High-throughput

0.523

High

686538

FBLN5
Fibulin-5

1

5

High-throughput

0.523

High

686436

TADBP
TAR DNA-binding protein 43

1

3

High-throughput

0.515

High

686544

DNM3A
DNA

1

1

High-throughput

0.515

High

686529

DPY30
Protein dpy-30 homolog

1

1

High-throughput

0.508

High

550327

ZEP1
Zinc finger protein 40

1

12

High-throughput

0.481

High

686445

PRIC4
Prickle-like protein 4

1

13

High-throughput

0.481

High

686494

ZNF34
Zinc finger protein 34

1

4

High-throughput

0.481

High

686427

H4
Histone H4

1

2

High-throughput

0.479

High

686428

RNF4
E3 ubiquitin-protein ligase RNF4

1

6

High-throughput

0.479

High

686432

EWS
RNA-binding protein EWS

1

6

High-throughput

0.479

High

686506

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

686540

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

484574

NT2NC
Notch homolog 2 N-terminal-like protein C

1

3

High-throughput

0.470

High

686429

KRT83
Keratin, type II cuticular Hb3

1

5

High-throughput

0.470

High

686435

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

1

5

High-throughput

0.470

High

686450

KRA63
Keratin-associated protein 6-3

1

1

High-throughput

0.470

High

686452

KR151
Keratin-associated protein 15-1

1

5

High-throughput

0.470

High

686498

OIT3
Oncoprotein-induced transcript 3 protein

1

6

High-throughput

0.470

High

686499

JPH3
Junctophilin-3

1

2

High-throughput

0.470

High

686517

KRA47
Keratin-associated protein 4-7

1

20

High-throughput

0.470

High

686524

KRA24
Keratin-associated protein 2-4

1

20

High-throughput

0.470

High

686537

NTRI
Neurotrimin

1

1

High-throughput

0.470

High

473266

KRA23
Keratin-associated protein 2-3

1

20

High-throughput

0.439

High

686420

KR103
Keratin-associated protein 10-3

1

20

High-throughput

0.439

High

686426

YPEL3
Protein yippee-like 3

1

1

High-throughput

0.439

High

686456

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

1

High-throughput

0.439

High

686486

NT2NA
Notch homolog 2 N-terminal-like protein A

1

3

High-throughput

0.439

High

686487

R144B
E3 ubiquitin-protein ligase RNF144B

1

3

High-throughput

0.439

High

686489

KR131
Keratin-associated protein 13-1

1

5

High-throughput

0.439

High

686527

TRI31
E3 ubiquitin-protein ligase TRIM31

1

5

High-throughput

0.437

High

686418

KR124
Keratin-associated protein 12-4

3

0

High-throughput

0.352

High

686478

KRA56
Keratin-associated protein 5-6

3

0

High-throughput

0.352

High

686542

CHIC2
Cysteine-rich hydrophobic domain-containing protein 2

3

0

High-throughput

0.348

High

150413

LCE2B
Late cornified envelope protein 2B

2

0

High-throughput

0.316

High

156135

TSN4
Tetraspanin-4

2

0

High-throughput

0.316

High

197590

ADA12
Disintegrin and metalloproteinase domain-containing protein 12

2

0

High-throughput

0.316

High

271954

CTAG2
Cancer/testis antigen 2

2

0

High-throughput

0.316

High

329198

CH25H
Cholesterol 25-hydroxylase

2

0

High-throughput

0.316

High

398496

PPB1
Alkaline phosphatase, placental type

2

0

High-throughput

0.316

High

686441

ETFD
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial

2

0

High-throughput

0.316

High

686447

KR192
Keratin-associated protein 19-2

2

0

High-throughput

0.316

High

686459

PKHG4
Puratrophin-1

2

0

High-throughput

0.316

High

686460

MIIP
Migration and invasion-inhibitory protein

2

0

High-throughput

0.316

High

686462

GT253
Inactive glycosyltransferase 25 family member 3

2

0

High-throughput

0.316

High

686464

KPRP
Keratinocyte proline-rich protein

2

0

High-throughput

0.316

High

686466

LCE1F
Late cornified envelope protein 1F

2

0

High-throughput

0.316

High

686474

SPRY7
SPRY domain-containing protein 7

2

0

High-throughput

0.316

High

686476

ATG9B
Autophagy-related protein 9B

2

0

High-throughput

0.316

High

686488

FA72B
Protein FAM72B

2

0

High-throughput

0.316

High

686490

KR111
Keratin-associated protein 11-1

2

0

High-throughput

0.316

High

686497

OXER1
Oxoeicosanoid receptor 1

2

0

High-throughput

0.316

High

686505

ARHGH
Rho guanine nucleotide exchange factor 17

2

0

High-throughput

0.316

High

686510

KR171
Keratin-associated protein 17-1

2

0

High-throughput

0.316

High

686526

RTN4R
Reticulon-4 receptor

2

0

High-throughput

0.316

High

686535

PRR13
Proline-rich protein 13

2

0

High-throughput

0.316

High

686469

LCE4A
Late cornified envelope protein 4A

1

0

High-throughput

0.299

High

686507

KCNKG
Potassium channel subfamily K member 16

1

0

High-throughput

0.299

High

583937

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

0

High-throughput

0.268

Low

620659

CPT2
Carnitine O-palmitoyltransferase 2, mitochondrial

1

0

High-throughput

0.268

Low

686411

MTR1B
Melatonin receptor type 1B

1

0

High-throughput

0.265

Low

486

NBPFJ
Neuroblastoma breakpoint family member 19

1

0

High-throughput

0.251

Low

229588

GRIN2
G protein-regulated inducer of neurite outgrowth 2

1

0

High-throughput

0.251

Low

686451

KR196
Keratin-associated protein 19-6

1

0

High-throughput

0.251

Low

686453

KR221
Keratin-associated protein 22-1

1

0

High-throughput

0.251

Low

686495

PRR22
Proline-rich protein 22

1

0

High-throughput

0.251

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024