HitPredict

Interactor 1: UBP19 (O94966)
Ubiquitin carboxyl-terminal hydrolase 19 (EC 3.4.19.12) (Deubiquitinating enzyme 19) (Ubiquitin thioesterase 19) (Ubiquitin-specific-processing protease 19) (Zinc finger MYND domain-containing protein 9)
Gene: USP19

Interactor 2: XIAP (P98170)
E3 ubiquitin-protein ligase XIAP (EC 2.3.2.27) (Baculoviral IAP repeat-containing protein 4) (IAP-like protein) (ILP) (hILP) (Inhibitor of apoptosis protein 3) (IAP-3) (hIAP-3) (hIAP3) (RING-type E3 ubiquitin transferase XIAP) (X-linked inhibitor of apoptosis protein) (X-linked IAP)
Gene: XIAP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21849505
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1318 Hs			1 497
+	Hs
		301386 UBP19_HUMAN (1-1318): 0: 1245: 100.00		BIRC2_HUMAN (3-497): 9.73e-82: 267: 23.31
+	Hs
		301385 UBP19_HUMAN (1-1318): 0: 1245: 100.00		BIRC3_HUMAN (150-394): 2.89e-41: 158: 23.94
+	Hs
		177638 UBP19_HUMAN (1-1318): 0: 1245: 100.00		BIRC5_HUMAN (266-372): 1.61e-21: 92.3: 26.32
+	Hs
		849996 UBP11_HUMAN (459-1228): 1.44e-151: 484: 30.84		XIAP_HUMAN (1-497): 0: 569: 100.00
+	Mm
		1141990 UBP15_MOUSE (485-1219): 1.25e-154: 493: 33.42		XIAP_MOUSE (1-497): 0: 544: 88.73
+	Hs
		957751 UBP7_HUMAN (341-968): 5.24e-54: 208: 9.64		XIAP_HUMAN (1-497): 0: 569: 100.00
+	Hs
		1036377 UBP15_HUMAN (485-1219): 1.01e-155: 496: 33.42		BIRC2_HUMAN (3-497): 9.73e-82: 267: 23.31
+	Hs
		1036241 UBP15_HUMAN (485-1219): 1.01e-155: 496: 33.42		BIRC3_HUMAN (150-394): 2.89e-41: 158: 23.94
+	Hs
		1316186 UBP15_HUMAN (485-1219): 1.01e-155: 496: 33.42		RNF26_HUMAN (320-496): 6.59e-25: 108: 14.13
+	Hs
		1206095 UBP15_HUMAN (485-1219): 1.01e-155: 496: 33.42		MIB1_HUMAN (311-492): 5.04e-16: 83.1: 13.68
+	Hs
		1036312 UBP7_HUMAN (341-968): 5.24e-54: 208: 9.64		BIRC2_HUMAN (3-497): 9.73e-82: 267: 23.31
+	Hs
		271165 UBP2_HUMAN (796-1219): 6.05e-73: 257: 20.54		BIRC7_HUMAN (14-155): 1.47e-36: 138: 21.83
+	Hs
		1035953 UBP7_HUMAN (341-968): 5.24e-54: 208: 9.64		BIRC3_HUMAN (150-394): 2.89e-41: 158: 23.94
+	Hs
		271121 UBP2_HUMAN (796-1219): 6.05e-73: 257: 20.54		LRSM1_HUMAN (330-497): 2.09e-24: 108: 18.45
+	Hs
		777082 UBP8_HUMAN (781-1222): 3.94e-67: 250: 19.39		BIRC6_HUMAN (258-442): 3.1e-26: 115: 18.78
+	Hs
		271156 UBP2_HUMAN (796-1219): 6.05e-73: 257: 20.54		MYLIP_HUMAN (430-496): 3.78e-23: 103: 35.82
+	Hs
		177733 UBP22_HUMAN (458-838): 9.18e-65: 231: 19.02		BIRC5_HUMAN (266-372): 1.61e-21: 92.3: 26.32
+	Hs
		1165224 UBP21_HUMAN (1049-1223): 2.15e-51: 193: 34.86		LRSM1_HUMAN (330-497): 2.09e-24: 108: 18.45
+	Hs
		1264871 UBP7_HUMAN (341-968): 5.24e-54: 208: 9.64		RFFL_HUMAN (446-497): 3.49e-18: 88: 44.23
+	Hs
		1174178 UBP43_HUMAN (1019-1270): 6.95e-51: 198: 28.00		RFFL_HUMAN (446-497): 3.49e-18: 88: 44.23