HitPredict

Interactor 1: UBP19 (O94966)
Ubiquitin carboxyl-terminal hydrolase 19 (EC 3.4.19.12) (Deubiquitinating enzyme 19) (Ubiquitin thioesterase 19) (Ubiquitin-specific-processing protease 19) (Zinc finger MYND domain-containing protein 9)
Gene: USP19

Interactor 2: BIRC2 (Q13490)
Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (IAP homolog B) (Inhibitor of apoptosis protein 2) (hIAP-2) (hIAP2) (RING finger protein 48) (RING-type E3 ubiquitin transferase BIRC2) (TNFR2-TRAF-signaling complex protein 2)
Gene: BIRC2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21849505
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1318 Hs			1 618
+	Hs
		301385 UBP19_HUMAN (1-1318): 0: 1245: 100.00		BIRC3_HUMAN (5-259): 2.61e-52: 191: 28.03
+	Hs
		301374 UBP19_HUMAN (1-1318): 0: 1245: 100.00		XIAP_HUMAN (17-173): 6.46e-31: 128: 29.38
+	Hs
		177638 UBP19_HUMAN (1-1318): 0: 1245: 100.00		BIRC5_HUMAN (267-346): 2.28e-22: 95.4: 34.12
+	Hs
		1036377 UBP15_HUMAN (485-1219): 1.01e-155: 496: 33.42		BIRC2_HUMAN (1-618): 0: 702: 100.00
+	Hs
		1036312 UBP7_HUMAN (341-968): 5.24e-54: 208: 9.64		BIRC2_HUMAN (1-618): 0: 702: 100.00
+	Hs
		1206095 UBP15_HUMAN (485-1219): 1.01e-155: 496: 33.42		MIB1_HUMAN (231-616): 1.49e-51: 193: 15.83
+	Hs
		1036241 UBP15_HUMAN (485-1219): 1.01e-155: 496: 33.42		BIRC3_HUMAN (5-259): 2.61e-52: 191: 28.03
+	Hs
		963037 UBP15_HUMAN (485-1219): 1.01e-155: 496: 33.42		MDM2_HUMAN (344-617): 6.07e-34: 137: 15.56
+	Mm
		1141990 UBP15_MOUSE (485-1219): 1.25e-154: 493: 33.42		XIAP_MOUSE (20-173): 1.62e-31: 130: 28.66
+	Hs
		849996 UBP11_HUMAN (459-1228): 1.44e-151: 484: 30.84		XIAP_HUMAN (17-173): 6.46e-31: 128: 29.38
+	Hs
		1035953 UBP7_HUMAN (341-968): 5.24e-54: 208: 9.64		BIRC3_HUMAN (5-259): 2.61e-52: 191: 28.03
+	Hs
		271073 UBP2_HUMAN (796-1219): 6.05e-73: 257: 20.54		MDM2_HUMAN (344-617): 6.07e-34: 137: 15.56
+	Hs
		271165 UBP2_HUMAN (796-1219): 6.05e-73: 257: 20.54		BIRC7_HUMAN (299-618): 4.32e-34: 133: 20.94
+	Hs
		777082 UBP8_HUMAN (781-1222): 3.94e-67: 250: 19.39		BIRC6_HUMAN (34-167): 3.57e-31: 132: 19.42
+	Hs
		271156 UBP2_HUMAN (796-1219): 6.05e-73: 257: 20.54		MYLIP_HUMAN (558-617): 3.91e-22: 101: 41.67
+	Mm
		620848 UBP7_MOUSE (341-968): 2.95e-54: 209: 9.64		MDM2_MOUSE (319-617): 5.64e-35: 140: 16.21
+	Hs
		962904 UBP7_HUMAN (341-968): 5.24e-54: 208: 9.64		MDM2_HUMAN (344-617): 6.07e-34: 137: 15.56
+	Hs
		957751 UBP7_HUMAN (341-968): 5.24e-54: 208: 9.64		XIAP_HUMAN (17-173): 6.46e-31: 128: 29.38
+	Hs
		177733 UBP22_HUMAN (458-838): 9.18e-65: 231: 19.02		BIRC5_HUMAN (267-346): 2.28e-22: 95.4: 34.12
+	Hs
		1264871 UBP7_HUMAN (341-968): 5.24e-54: 208: 9.64		RFFL_HUMAN (567-618): 2.51e-17: 85.8: 42.31