HitPredict

Interactor 1: TRI37 (O94972)
E3 ubiquitin-protein ligase TRIM37 (EC 2.3.2.27) (Mulibrey nanism protein) (RING-type E3 ubiquitin transferase TRIM37) (Tripartite motif-containing protein 37)
Gene: TRIM37

Interactor 2: UB2E2 (Q96LR5)
Ubiquitin-conjugating enzyme E2 E2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E2) (UbcH8) (Ubiquitin carrier protein E2) (Ubiquitin-protein ligase E2)
Gene: UBE2E2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	21143188
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 964 Hs			1 201
+	Hs
		301956 TRI37_HUMAN (1-964): 0: 1280: 100.00		UB2E3_HUMAN (1-201): 6.37e-85: 251: 79.71
+	Hs
		301733 TRI37_HUMAN (1-964): 0: 1280: 100.00		UB2D2_HUMAN (55-200): 2.8e-82: 242: 64.38
+	Hs
		301690 TRI37_HUMAN (1-964): 0: 1280: 100.00		UB2D1_HUMAN (55-200): 1.23e-81: 240: 61.64
+	Hs
		301691 TRI37_HUMAN (1-964): 0: 1280: 100.00		UB2E1_HUMAN (28-201): 6.5e-80: 238: 89.71
+	Hs
		301711 TRI37_HUMAN (1-964): 0: 1280: 100.00		UB2D3_HUMAN (55-200): 1.28e-80: 238: 63.70
+	Hs
		1285831 TRI43_HUMAN (1-372): 1.51e-75: 257: 17.36		UB2D4_HUMAN (55-200): 9.37e-83: 243: 63.01
+	Hs
		919816 TRI43_HUMAN (1-372): 1.51e-75: 257: 17.36		UB2D2_HUMAN (55-200): 2.8e-82: 242: 64.38
+	Hs
		849399 TRI43_HUMAN (1-372): 1.51e-75: 257: 17.36		UB2D1_HUMAN (55-200): 1.23e-81: 240: 61.64
+	Hs
		919822 TRI11_HUMAN (1-360): 2.21e-74: 254: 16.04		UB2D2_HUMAN (55-200): 2.8e-82: 242: 64.38
+	Hs
		895870 TRI43_HUMAN (1-372): 1.51e-75: 257: 17.36		UB2D3_HUMAN (55-200): 1.28e-80: 238: 63.70
+	Hs
		849406 TRI11_HUMAN (1-360): 2.21e-74: 254: 16.04		UB2D1_HUMAN (55-200): 1.23e-81: 240: 61.64
+	Hs
		851867 TRI11_HUMAN (1-360): 2.21e-74: 254: 16.04		UB2E1_HUMAN (28-201): 6.5e-80: 238: 89.71
+	Hs
		895876 TRI11_HUMAN (1-360): 2.21e-74: 254: 16.04		UB2D3_HUMAN (55-200): 1.28e-80: 238: 63.70
+	Hs
		536779 TRI27_HUMAN (1-373): 2.44e-71: 247: 16.00		UB2D2_HUMAN (55-200): 2.8e-82: 242: 64.38
+	Hs
		536760 TRI27_HUMAN (1-373): 2.44e-71: 247: 16.00		UB2D1_HUMAN (55-200): 1.23e-81: 240: 61.64
+	Hs
		536763 TRI27_HUMAN (1-373): 2.44e-71: 247: 16.00		UB2E1_HUMAN (28-201): 6.5e-80: 238: 89.71
+	Hs
		536772 TRI27_HUMAN (1-373): 2.44e-71: 247: 16.00		UB2D3_HUMAN (55-200): 1.28e-80: 238: 63.70
+	Hs
		896517 TRI11_HUMAN (1-360): 2.21e-74: 254: 16.04		UBE2N_HUMAN (53-200): 2.86e-70: 212: 45.27
+	Hs
		536757 TRI27_HUMAN (1-373): 2.44e-71: 247: 16.00		UBE2A_HUMAN (54-198): 1.67e-70: 212: 35.86
+	Hs
		536774 TRI27_HUMAN (1-373): 2.44e-71: 247: 16.00		UBE2N_HUMAN (53-200): 2.86e-70: 212: 45.27