HitPredict

Interactor 1: SC31A (O94979)
Protein transport protein Sec31A (ABP125) (ABP130) (SEC31-like protein 1) (SEC31-related protein A) (Web1-like protein)
Gene: SEC31A

Interactor 2: NTRK1 (P04629)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (TRK1-transforming tyrosine kinase protein) (Tropomyosin-related kinase A) (Tyrosine kinase receptor) (Tyrosine kinase receptor A) (Trk-A) (gp140trk) (p140-TrkA)
Gene: NTRK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	25921289, 35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1220 Hs			1 796
+	Hs
		302247 SC31A_HUMAN (1-1220): 0: 830: 100.00		FGFR1_HUMAN (195-794): 0: 545: 26.34
+	Hs
		302291 SC31A_HUMAN (1-1220): 0: 830: 100.00		NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37
+	Hs
		302255 SC31A_HUMAN (1-1220): 0: 830: 100.00		FGFR4_HUMAN (140-795): 7.96e-168: 506: 25.59
+	Hs
		302241 SC31A_HUMAN (1-1220): 0: 830: 100.00		RET_HUMAN (391-794): 3.5e-114: 374: 30.44
+	Hs
		302242 SC31A_HUMAN (1-1220): 0: 830: 100.00		IGF1R_HUMAN (493-777): 6.97e-71: 255: 42.61
+	Hs
		302332 SC31A_HUMAN (1-1220): 0: 830: 100.00		ALK_HUMAN (505-790): 8.72e-63: 231: 42.07
+	Rn
		102464 G3V699_RAT (1-1220): 0: 769: 87.38		INSR_RAT (493-777): 7.31e-66: 241: 41.95
+	Hs
		169154 SC31A_HUMAN (1-1220): 0: 830: 100.00		MUSK_HUMAN (171-374): 2.86e-13: 75.8: 18.61
+	Hs
		384726 RBBP4_HUMAN (9-349): 7.97e-83: 279: 17.49		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		385480 TBL1R_HUMAN (17-335): 7.88e-65: 231: 15.51		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		384596 WDR5_HUMAN (206-522): 2.88e-60: 212: 14.95		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		384386 COPB2_HUMAN (1-243): 1.76e-41: 167: 12.30		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		507887 COPB2_HUMAN (1-243): 1.76e-41: 167: 12.30		FGFR1_HUMAN (195-794): 0: 545: 26.34
+	Hs
		384438 LIS1_HUMAN (331-619): 6.2e-16: 83.4: 7.74		NTRK1_HUMAN (1-796): 0: 621: 100.00
+	Hs
		725460 COPB2_HUMAN (1-243): 1.76e-41: 167: 12.30		NTRK3_HUMAN (36-796): 1.63e-174: 525: 49.37
+	Hs
		609202 LIS1_HUMAN (331-619): 6.2e-16: 83.4: 7.74		FGFR3_HUMAN (168-794): 3.98e-158: 481: 25.98
+	Hs
		411323 COPB2_HUMAN (1-243): 1.76e-41: 167: 12.30		INSR_HUMAN (493-777): 3e-68: 248: 42.62
+	Hs
		725611 COPB2_HUMAN (1-243): 1.76e-41: 167: 12.30		ALK_HUMAN (505-790): 8.72e-63: 231: 42.07
+	Hs
		169165 COPB2_HUMAN (1-243): 1.76e-41: 167: 12.30		MUSK_HUMAN (171-374): 2.86e-13: 75.8: 18.61