HitPredict

Interactor 1: SC31A (O94979)
Protein transport protein Sec31A (ABP125) (ABP130) (SEC31-like protein 1) (SEC31-related protein A) (Web1-like protein)
Gene: SEC31A

Interactor 2: RET (P07949)
Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1) (Cadherin family member 12) (Proto-oncogene c-Ret) [Cleaved into: Soluble RET kinase fragment; Extracellular cell-membrane anchored RET cadherin 120 kDa fragment]
Gene: RET

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1220 Hs			1 1114
+	Hs
		302247 SC31A_HUMAN (1-1220): 0: 830: 100.00		FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61
+	Hs
		302237 SC31A_HUMAN (1-1220): 0: 830: 100.00		ERBB2_HUMAN (428-1113): 6.03e-140: 456: 24.93
+	Hs
		302238 SC31A_HUMAN (1-1220): 0: 830: 100.00		NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69
+	Hs
		169154 SC31A_HUMAN (1-1220): 0: 830: 100.00		MUSK_HUMAN (396-1018): 1.21e-135: 434: 25.28
+	Hs
		302255 SC31A_HUMAN (1-1220): 0: 830: 100.00		FGFR4_HUMAN (535-1054): 4.33e-124: 401: 37.89
+	Hs
		302291 SC31A_HUMAN (1-1220): 0: 830: 100.00		NTRK3_HUMAN (638-1020): 2.11e-106: 355: 31.19
+	Hs
		302261 SC31A_HUMAN (1-1220): 0: 830: 100.00		VGFR3_HUMAN (677-1012): 1.84e-76: 278: 41.25
+	Hs
		384726 RBBP4_HUMAN (9-349): 7.97e-83: 279: 17.49		NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69
+	Hs
		385480 TBL1R_HUMAN (17-335): 7.88e-65: 231: 15.51		NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69
+	Hs
		384596 WDR5_HUMAN (206-522): 2.88e-60: 212: 14.95		NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69
+	Hs
		507887 COPB2_HUMAN (1-243): 1.76e-41: 167: 12.30		FGFR1_HUMAN (501-1061): 2.81e-150: 471: 32.61
+	Hs
		384386 COPB2_HUMAN (1-243): 1.76e-41: 167: 12.30		NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69
+	Hs
		169165 COPB2_HUMAN (1-243): 1.76e-41: 167: 12.30		MUSK_HUMAN (396-1018): 1.21e-135: 434: 25.28
+	Hs
		609202 LIS1_HUMAN (331-619): 6.2e-16: 83.4: 7.74		FGFR3_HUMAN (501-1061): 4.63e-147: 462: 33.16
+	Hs
		383677 LIS1_HUMAN (331-619): 6.2e-16: 83.4: 7.74		ERBB2_HUMAN (428-1113): 6.03e-140: 456: 24.93
+	Hs
		384438 LIS1_HUMAN (331-619): 6.2e-16: 83.4: 7.74		NTRK1_HUMAN (383-1018): 3.43e-142: 449: 23.69
+	Hs
		725460 COPB2_HUMAN (1-243): 1.76e-41: 167: 12.30		NTRK3_HUMAN (638-1020): 2.11e-106: 355: 31.19
+	Hs
		725373 COPB2_HUMAN (1-243): 1.76e-41: 167: 12.30		VGFR3_HUMAN (677-1012): 1.84e-76: 278: 41.25
+	Hs
		572595 LIS1_HUMAN (331-619): 6.2e-16: 83.4: 7.74		VGFR1_HUMAN (716-1026): 5.28e-79: 285: 41.71
+	Hs
		738171 LIS1_HUMAN (331-619): 6.2e-16: 83.4: 7.74		FLT3_HUMAN (714-1014): 2.21e-72: 262: 40.00