HitPredict

Interactor 1: HEXI1 (O94992)
Protein HEXIM1 (Cardiac lineage protein 1) (Estrogen down-regulated gene 1 protein) (Hexamethylene bis-acetamide-inducible protein 1) (Menage a quatre protein 1)
Gene: HEXIM1

Interactor 2: NONO (Q15233)
Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit)
Gene: NONO

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	29845934, 24981860
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002218 - activation of innate immune response GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045087 - innate immune response GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 359 Hs			1 471
+	Hs
		303210 HEXI1_HUMAN (1-359): 5.52e-159: 451: 100.00		PABP4_HUMAN (66-467): 1.55e-70: 237: 15.42
+	Hs
		303381 HEXI1_HUMAN (1-359): 5.52e-159: 451: 100.00		PSPC1_HUMAN (20-470): 2.17e-67: 226: 58.41
+	Hs
		302844 HEXI1_HUMAN (1-359): 5.52e-159: 451: 100.00		PABP1_HUMAN (66-459): 7.11e-65: 222: 14.89
+	Hs
		303480 HEXI1_HUMAN (1-359): 5.52e-159: 451: 100.00		PABP3_HUMAN (66-459): 5.94e-61: 211: 13.88
+	Hs
		302908 HEXI1_HUMAN (1-359): 5.52e-159: 451: 100.00		SFPQ_HUMAN (45-471): 3.15e-53: 192: 56.92
+	Hs
		303287 HEXI1_HUMAN (1-359): 5.52e-159: 451: 100.00		PAP1L_HUMAN (7-161): 7.22e-16: 82.3: 18.24
+	Hs
		303462 HEXI1_HUMAN (1-359): 5.52e-159: 451: 100.00		RBM4_HUMAN (75-182): 7.64e-09: 59.3: 35.71