HitPredict

Interactor 1: SOX30 (O94993)
Transcription factor SOX-30
Gene: SOX30

Interactor 2: PAXI1 (Q6ZW49)
PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein)
Gene: PAXIP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	22990118
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 753 Hs			1 1069
+	Hs
		881812 SOX10_HUMAN (278-709): 8.9e-40: 155: 17.69		PAXI1_HUMAN (1-419): 4.99e-91: 316: 100.00
+	Hs
		1173211 CIC_HUMAN (288-578): 1.57e-36: 150: 19.60		PAXI1_HUMAN (1-419): 4.99e-91: 316: 100.00
+	Hs
		225751 SOX15_HUMAN (300-509): 1.49e-39: 147: 26.58		PAXI1_HUMAN (1-419): 4.99e-91: 316: 100.00
+	Hs
		818814 SOX9_HUMAN (247-708): 9.78e-36: 144: 15.48		PAXI1_HUMAN (1-419): 4.99e-91: 316: 100.00
+	Hs
		1173240 SOX17_HUMAN (303-618): 8.33e-36: 142: 15.73		PAXI1_HUMAN (1-419): 4.99e-91: 316: 100.00
+	Hs
		1173227 SOX7_HUMAN (312-646): 1.29e-35: 141: 21.85		PAXI1_HUMAN (1-419): 4.99e-91: 316: 100.00
+	Hs
		1056996 TF7L2_HUMAN (223-598): 1.34e-41: 163: 17.97		MDC1_HUMAN (187-1069): 1.3e-57: 220: 14.77
+	Hs
		881831 SOX10_HUMAN (278-709): 8.9e-40: 155: 17.69		CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07
+	Hs
		1300971 CIC_HUMAN (288-578): 1.57e-36: 150: 19.60		CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07
+	Hs
		727814 SOX5_HUMAN (308-516): 5.84e-37: 150: 22.38		CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07
+	Hs
		727934 SOX6_HUMAN (293-556): 1.53e-36: 149: 23.51		CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07
+	Hs
		818841 SOX9_HUMAN (247-708): 9.78e-36: 144: 15.48		CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07
+	Hs
		1332326 SOX17_HUMAN (303-618): 8.33e-36: 142: 15.73		CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07
+	Hs
		1311936 SOX7_HUMAN (312-646): 1.29e-35: 141: 21.85		CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07
+	Hs
		124109 SPT5H_HUMAN (427-665): 8.48e-30: 129: 18.03		CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07
+	Hs
		867119 CIC_HUMAN (288-578): 1.57e-36: 150: 19.60		SC24C_HUMAN (182-460): 3.09e-12: 73.2: 8.84
+	Hs
		300546 CIC_HUMAN (288-578): 1.57e-36: 150: 19.60		NFAT5_HUMAN (180-600): 4.53e-12: 72.7: 15.29
+	Hs
		818819 SOX9_HUMAN (247-708): 9.78e-36: 144: 15.48		KMT2C_HUMAN (162-612): 3.03e-12: 73.5: 9.11
+	Hs
		1243843 SOX17_HUMAN (303-618): 8.33e-36: 142: 15.73		KMT2C_HUMAN (162-612): 3.03e-12: 73.5: 9.11
+	Hs
		1243837 SOX7_HUMAN (312-646): 1.29e-35: 141: 21.85		KMT2C_HUMAN (162-612): 3.03e-12: 73.5: 9.11