Protein: RFC5
Replication factor C subunit 5 (Activator 1 36 kDa subunit) (A1 36 kDa subunit) (Activator 1 subunit 5) (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36)

Gene: RFC5
Organism: Homo sapiens
Interactions: 197
UniProt ID: P40937

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003689 - DNA clamp loader activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

721936

RFC4
Replication factor C subunit 4

15

16

Small-scale

0.986

High

722071

RFC2
Replication factor C subunit 2

7

16

Small-scale

0.956

High

777906

ATAD5
ATPase family AAA domain-containing protein 5

4

20

Small-scale

0.895

High

517114

PCNA
Proliferating cell nuclear antigen

4

12

Small-scale

0.882

High

777901

CTF18
Chromosome transmission fidelity protein 18 homolog

3

17

Small-scale

0.879

High

777822

RFC3
Replication factor C subunit 3

3

16

High-throughput

0.861

High

722179

RFC1
Replication factor C subunit 1

3

20

Small-scale

0.855

High

226739

PRKN
E3 ubiquitin-protein ligase parkin

2

8

High-throughput

0.754

High

777843

XIAP
E3 ubiquitin-protein ligase XIAP

5

6

High-throughput

0.722

High

279002

RAD17
Cell cycle checkpoint protein RAD17

5

20

Small-scale

0.721

High

244054

BRD4
Bromodomain-containing protein 4

4

10

Small-scale

0.698

High

135011

TRI38
E3 ubiquitin-protein ligase TRIM38

5

0

High-throughput

0.691

High

777868

NAB2
NGFI-A-binding protein 2

5

0

High-throughput

0.691

High

650557

RFA1
Replication protein A 70 kDa DNA-binding subunit

4

3

Small-scale

0.686

High

777916

DCC1
Sister chromatid cohesion protein DCC1

3

7

High-throughput

0.667

High

719862

RFA3
Replication protein A 14 kDa subunit

3

3

High-throughput

0.656

High

552126

RFA2
Replication protein A 32 kDa subunit

3

5

High-throughput

0.640

High

474571

CTF8
Chromosome transmission fidelity protein 8 homolog

2

2

High-throughput

0.628

High

475441

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

4

High-throughput

0.618

High

777831

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.618

High

777947

RUVB2
RuvB-like 2

1

11

High-throughput

0.618

High

245887

HUS1
Checkpoint protein HUS1

2

2

Small-scale

0.611

High

346129

MYC
Myc proto-oncogene protein

2

3

High-throughput

0.611

High

455173

PARP1
Poly [ADP-ribose] polymerase 1

2

11

High-throughput

0.611

High

777855

CUL3
Cullin-3

2

5

High-throughput

0.611

High

777912

RAD9A
Cell cycle checkpoint control protein RAD9A

2

3

Small-scale

0.611

High

777846

ARI5A
AT-rich interactive domain-containing protein 5A

2

1

High-throughput

0.606

High

777849

STF1
Steroidogenic factor 1

2

5

High-throughput

0.606

High

777853

BIRC2
Baculoviral IAP repeat-containing protein 2

2

6

High-throughput

0.606

High

777879

TASO2
Protein TASOR 2

2

1

High-throughput

0.606

High

777908

PP16B
Protein phosphatase 1 regulatory inhibitor subunit 16B

2

3

High-throughput

0.606

High

414201

RB
Retinoblastoma-associated protein

2

0

High-throughput

0.602

High

777838

H4
Histone H4

2

7

High-throughput

0.584

High

777841

H31
Histone H3.1

2

13

High-throughput

0.584

High

777930

ECT2
Protein ECT2

2

3

High-throughput

0.584

High

777938

ANLN
Anillin

2

3

High-throughput

0.584

High

777941

MCM9
DNA helicase MCM9

2

4

Small-scale

0.584

High

777943

ZRAN1
Ubiquitin thioesterase ZRANB1

2

4

High-throughput

0.584

High

563365

ZNF19
Zinc finger protein 19

2

0

High-throughput

0.580

High

624406

CCNC
Cyclin-C

2

0

High-throughput

0.580

High

777881

XAF1
XIAP-associated factor 1

2

0

High-throughput

0.580

High

777899

LMO3
LIM domain only protein 3

2

0

High-throughput

0.580

High

777903

EXOS8
Exosome complex component RRP43

2

0

High-throughput

0.580

High

777911

TSNAX
Translin-associated protein X

2

0

High-throughput

0.580

High

777915

ZN426
Zinc finger protein 426

2

0

High-throughput

0.580

High

369124

ESR1
Estrogen receptor

2

6

High-throughput

0.571

High

403812

ITB1
Integrin beta-1

2

1

High-throughput

0.549

High

777840

EF1A1
Elongation factor 1-alpha 1

1

1

High-throughput

0.541

High

777830

DAPK1
Death-associated protein kinase 1

1

2

High-throughput

0.536

High

133362

NOP56
Nucleolar protein 56

1

3

High-throughput

0.536

High

418004

NPM
Nucleophosmin

1

3

High-throughput

0.536

High

469961

H2AZ
Histone H2A.Z

1

5

High-throughput

0.536

High

508378

TOP1
DNA topoisomerase 1

1

2

High-throughput

0.536

High

528712

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.536

High

564823

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

High-throughput

0.536

High

649349

RL10
Large ribosomal subunit protein uL16

1

3

High-throughput

0.536

High

777829

HDGF
Hepatoma-derived growth factor

1

2

High-throughput

0.536

High

777839

RACK1
Small ribosomal subunit protein RACK1

1

3

High-throughput

0.536

High

777844

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

3

High-throughput

0.536

High

777847

SSRP1
FACT complex subunit SSRP1

1

11

High-throughput

0.536

High

777862

NUMA1
Nuclear mitotic apparatus protein 1

1

1

High-throughput

0.536

High

777870

H2B2E
Histone H2B type 2-E

1

14

High-throughput

0.536

High

777890

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

High-throughput

0.536

High

777891

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

2

High-throughput

0.536

High

777919

UBXN6
UBX domain-containing protein 6

1

1

High-throughput

0.536

High

777952

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

2

High-throughput

0.536

High

777872

RBM48
RNA-binding protein 48

1

0

High-throughput

0.518

High

777887

CSN6
COP9 signalosome complex subunit 6

1

0

High-throughput

0.518

High

777949

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.518

High

777913

AKAP9
A-kinase anchor protein 9

1

4

High-throughput

0.515

High

777856

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.513

High

777923

NUCKS
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1

1

0

High-throughput

0.513

High

777948

DRG1
Developmentally-regulated GTP-binding protein 1

1

0

High-throughput

0.513

High

777834

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

2

High-throughput

0.501

High

777836

SUMO2
Small ubiquitin-related modifier 2

1

3

High-throughput

0.501

High

639556

TNR5
Tumor necrosis factor receptor superfamily member 5

1

0

High-throughput

0.493

High

777924

GO45
Golgin-45

1

0

High-throughput

0.493

High

777932

EAF6
Chromatin modification-related protein MEAF6

1

0

High-throughput

0.493

High

456395

PPBI
Intestinal-type alkaline phosphatase

1

1

High-throughput

0.489

High

777859

I13R2
Interleukin-13 receptor subunit alpha-2

1

2

High-throughput

0.489

High

777920

DNAI2
Dynein axonemal intermediate chain 2

1

1

High-throughput

0.489

High

777944

SRP68
Signal recognition particle subunit SRP68

1

1

High-throughput

0.489

High

122537

MEN1
Menin

1

3

High-throughput

0.479

High

125208

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

4

High-throughput

0.479

High

148484

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.479

High

179570

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

4

High-throughput

0.479

High

233262

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

238258

RAD1
Cell cycle checkpoint protein RAD1

1

2

Small-scale

0.479

High

267938

EED
Polycomb protein EED

1

4

High-throughput

0.479

High

272506

OFD1
Centriole and centriolar satellite protein OFD1

1

4

High-throughput

0.479

High

282564

RNF8
E3 ubiquitin-protein ligase RNF8

1

3

High-throughput

0.479

High

294476

RECQ4
ATP-dependent DNA helicase Q4

1

5

High-throughput

0.479

High

298238

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.479

High

302989

HEXI1
Protein HEXIM1

1

2

High-throughput

0.479

High

317923

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

6

High-throughput

0.479

High

338064

EGFR
Epidermal growth factor receptor

1

7

High-throughput

0.479

High

384418

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.479

High

391584

H2A1B
Histone H2A type 1-B/E

1

7

High-throughput

0.479

High

441923

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

3

High-throughput

0.479

High

590679

BTF3
Transcription factor BTF3

1

2

High-throughput

0.479

High

622381

CCND1
G1/S-specific cyclin-D1

1

2

High-throughput

0.479

High

631367

BRD2
Bromodomain-containing protein 2

1

16

High-throughput

0.479

High

707542

H2B1B
Histone H2B type 1-B

1

14

High-throughput

0.479

High

718573

PHB1
Prohibitin 1

1

2

High-throughput

0.479

High

777823

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

777824

NKX21
Homeobox protein Nkx-2.1

1

4

High-throughput

0.479

High

777825

SOX2
Transcription factor SOX-2

1

11

High-throughput

0.479

High

777826

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

4

High-throughput

0.479

High

777827

CENPA
Histone H3-like centromeric protein A

1

13

High-throughput

0.479

High

777832

FOXA1
Hepatocyte nuclear factor 3-alpha

1

1

High-throughput

0.479

High

777837

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

777842

H33
Histone H3.3

1

13

High-throughput

0.479

High

777845

KIF23
Kinesin-like protein KIF23

1

2

High-throughput

0.479

High

777848

TIF1B
Transcription intermediary factor 1-beta

1

5

High-throughput

0.479

High

777851

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

6

High-throughput

0.479

High

777852

BIRC3
Baculoviral IAP repeat-containing protein 3

1

6

High-throughput

0.479

High

777854

SNW1
SNW domain-containing protein 1

1

3

High-throughput

0.479

High

777858

HLTF
Helicase-like transcription factor

1

7

High-throughput

0.479

High

777860

MDC1
Mediator of DNA damage checkpoint protein 1

1

5

High-throughput

0.479

High

777863

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

3

High-throughput

0.479

High

777864

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

777865

BRD3
Bromodomain-containing protein 3

1

13

High-throughput

0.479

High

777866

PCBP1
Poly(rC)-binding protein 1

1

2

High-throughput

0.479

High

777869

HIF1A
Hypoxia-inducible factor 1-alpha

1

4

High-throughput

0.479

High

777878

MYSM1
Deubiquitinase MYSM1

1

3

Small-scale

0.479

High

777882

ZN746
Zinc finger protein 746

1

1

High-throughput

0.479

High

777886

MEPCE
7SK snRNA methylphosphate capping enzyme

1

2

High-throughput

0.479

High

777888

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.479

High

777889

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

4

High-throughput

0.479

High

777894

ZBT38
Zinc finger and BTB domain-containing protein 38

1

2

Small-scale

0.479

High

777898

COP1
E3 ubiquitin-protein ligase COP1

1

1

High-throughput

0.479

High

777900

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.479

High

777902

ESR2
Estrogen receptor beta

1

6

High-throughput

0.479

High

777907

CIC
Protein capicua homolog

1

9

High-throughput

0.479

High

777910

CDC5L
Cell division cycle 5-like protein

1

3

High-throughput

0.479

High

777914

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

5

High-throughput

0.479

High

777917

TRAIP
E3 ubiquitin-protein ligase TRAIP

1

3

Small-scale

0.479

High

777918

FACD2
Fanconi anemia group D2 protein

1

7

High-throughput

0.479

High

777921

SPRTN
DNA-dependent metalloprotease SPRTN

1

3

High-throughput

0.479

High

777922

CCDC8
Coiled-coil domain-containing protein 8

1

2

High-throughput

0.479

High

777925

Q9H4D1
Protein kinase

1

2

High-throughput

0.479

High

777926

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

5

High-throughput

0.479

High

777933

PIDD1
p53-induced death domain-containing protein 1

1

1

Small-scale

0.479

High

777934

RC3H2
Roquin-2

1

5

High-throughput

0.479

High

777939

FBX6
F-box only protein 6

1

1

High-throughput

0.479

High

777942

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

777946

FZR1
Fizzy-related protein homolog

1

4

High-throughput

0.479

High

777950

ZN330
Zinc finger protein 330

1

1

High-throughput

0.479

High

777951

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.479

High

777953

MAFB
Transcription factor MafB

1

7

High-throughput

0.479

High

2794

A0A0C4DGQ7
EMAP like 2

1

2

High-throughput

0.470

High

777871

ZMAT1
Zinc finger matrin-type protein 1

1

0

High-throughput

0.460

High

777873

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.460

High

209736

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

750158

COIL
Coilin

1

0

High-throughput

0.458

High

777867

T22D1
TSC22 domain family protein 1

1

0

High-throughput

0.458

High

777893

NIN
Ninein

1

0

High-throughput

0.458

High

777896

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

777909

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

777929

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

777935

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.458

High

777877

RIF1
Telomere-associated protein RIF1

1

3

High-throughput

0.457

High

256951

KDM4A
Lysine-specific demethylase 4A

1

6

Small-scale

0.445

High

401564

JUN
Transcription factor Jun

1

5

High-throughput

0.445

High

777833

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

2

High-throughput

0.445

High

777861

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

2

High-throughput

0.445

High

777931

LN28A
Protein lin-28 homolog A

1

2

High-throughput

0.445

High

325557

EMAL2
Echinoderm microtubule-associated protein-like 2

1

1

High-throughput

0.439

High

777857

TRI29
Tripartite motif-containing protein 29

1

4

Small-scale

0.437

High

777875

RC3H1
Roquin-1

1

2

High-throughput

0.437

High

777880

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.437

High

777885

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

777905

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.437

High

777927

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.437

High

777928

RPAP3
RNA polymerase II-associated protein 3

1

1

High-throughput

0.437

High

777937

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

2

High-throughput

0.437

High

777945

HECD1
E3 ubiquitin-protein ligase HECTD1

1

7

High-throughput

0.437

High

777828

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.408

High

960

SIM26
Small integral membrane protein 26

1

2

High-throughput

0.407

High

306009

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

2

High-throughput

0.407

High

777874

LITD1
LINE-1 type transposase domain-containing protein 1

1

1

High-throughput

0.407

High

777883

NBEL2
Neurobeachin-like protein 2

1

2

High-throughput

0.407

High

67780

CMI2B
Ciliary microtubule inner protein 2B

2

0

High-throughput

0.316

High

165756

N4BP3
NEDD4-binding protein 3

2

0

High-throughput

0.316

High

280538

KRT34
Keratin, type I cuticular Ha4

2

0

High-throughput

0.316

High

777904

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.316

High

777850

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.282

High

777876

PI3R6
Phosphoinositide 3-kinase regulatory subunit 6

1

0

High-throughput

0.269

Low

777884

CAN12
Calpain-12

1

0

High-throughput

0.269

Low

777835

YPEL3
Protein yippee-like 3

1

0

High-throughput

0.251

Low

118223

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.249

Low

255567

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.249

Low

777892

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.249

Low

777936

CENPJ
Centromere protein J

1

0

High-throughput

0.249

Low

777940

MKS1
Tectonic-like complex member MKS1

1

0

High-throughput

0.249

Low

777895

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low

777897

ARK74
Aflatoxin B1 aldehyde reductase member 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024