HitPredict

Interactor 1: DIRA1 (O95057)
GTP-binding protein Di-Ras1 (Distinct subgroup of the Ras family member 1) (Ras-related inhibitor of cell growth) (Rig) (Small GTP-binding tumor suppressor 1)
Gene: DIRAS1

Interactor 2: ARL4C (P56559)
ADP-ribosylation factor-like protein 4C (ADP-ribosylation factor-like protein 7) (ADP-ribosylation factor-like protein LAK)
Gene: ARL4C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 198 Hs			1 192
+	Hs
		950495 RAB35_HUMAN (3-196): 3.21e-86: 254: 29.35		ARF1_HUMAN (1-183): 2.12e-89: 261: 45.46
+	Hs
		912914 RAB35_HUMAN (3-196): 3.21e-86: 254: 29.35		ARF6_HUMAN (1-181): 9.41e-87: 254: 43.65
+	Hs
		894718 RAB8A_HUMAN (4-198): 3.1e-80: 239: 26.34		ARF1_HUMAN (1-183): 2.12e-89: 261: 45.46
+	Hs
		894719 RAB8A_HUMAN (4-198): 3.1e-80: 239: 26.34		ARF5_HUMAN (1-182): 2.02e-87: 256: 45.06
+	Hs
		912837 RAB1A_HUMAN (2-196): 7e-80: 238: 28.71		ARF6_HUMAN (1-181): 9.41e-87: 254: 43.65
+	Hs
		918874 RAB35_HUMAN (3-196): 3.21e-86: 254: 29.35		RAB1A_HUMAN (1-185): 7.27e-70: 212: 23.12
+	Mm
		918986 RAB35_MOUSE (3-196): 3.21e-86: 254: 29.35		RAB1A_MOUSE (1-185): 7.27e-70: 212: 23.12
+	Hs
		830725 RAB13_HUMAN (4-197): 9.67e-80: 238: 29.00		ARL4D_HUMAN (5-192): 1.35e-75: 227: 59.04
+	Mm
		1161509 RAB35_MOUSE (3-196): 3.21e-86: 254: 29.35		RAB1B_MOUSE (14-185): 1.89e-68: 208: 23.70
+	Zm
		73944 B4FAE1_MAIZE (2-196): 6.37e-83: 245: 27.59		B4FAE1_MAIZE (14-190): 1.21e-70: 214: 23.60
+	Hs
		574682 RAB35_HUMAN (3-196): 3.21e-86: 254: 29.35		ARF4_HUMAN (1-182): 1.71e-66: 203: 43.96
+	Hs
		894715 RAB8A_HUMAN (4-198): 3.1e-80: 239: 26.34		RAB1A_HUMAN (1-185): 7.27e-70: 212: 23.12
+	Hs
		918846 RAB1A_HUMAN (2-196): 7e-80: 238: 28.71		RAB1A_HUMAN (1-185): 7.27e-70: 212: 23.12
+	Hs
		845881 RAB13_HUMAN (4-197): 9.67e-80: 238: 29.00		RAB1B_HUMAN (14-185): 8.05e-69: 210: 23.70
+	Mm
		919000 RAB1A_MOUSE (2-196): 7e-80: 238: 28.71		RAB1B_MOUSE (14-185): 1.89e-68: 208: 23.70
+	Hs
		574637 RAB8A_HUMAN (4-198): 3.1e-80: 239: 26.34		ARF4_HUMAN (1-182): 1.71e-66: 203: 43.96
+	Hs
		894712 RAB8A_HUMAN (4-198): 3.1e-80: 239: 26.34		RB11A_HUMAN (14-192): 1.89e-64: 199: 20.00
+	Hs
		845845 RAB13_HUMAN (4-197): 9.67e-80: 238: 29.00		RB11A_HUMAN (14-192): 1.89e-64: 199: 20.00
+	Hs
		913992 RAB1A_HUMAN (2-196): 7e-80: 238: 28.71		RB11A_HUMAN (14-192): 1.89e-64: 199: 20.00
+	Hs
		896605 RAB1A_HUMAN (2-196): 7e-80: 238: 28.71		RAB14_HUMAN (14-185): 4.33e-64: 198: 20.81