HitPredict

Interactor 1: DIRA1 (O95057)
GTP-binding protein Di-Ras1 (Distinct subgroup of the Ras family member 1) (Ras-related inhibitor of cell growth) (Rig) (Small GTP-binding tumor suppressor 1)
Gene: DIRAS1

Interactor 2: RABE2 (Q9H5N1)
Rab GTPase-binding effector protein 2 (Rabaptin-5beta)
Gene: RABEP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Rab5-bind~Ras
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 198 Hs			1 569
+	Hs
		1070238 RAB35_HUMAN (3-196): 3.21e-86: 254: 29.35		MRCKA_HUMAN (241-552): 1.9e-37: 150: 16.30
+	Hs
		914124 RB11A_HUMAN (3-196): 2.31e-76: 230: 27.27		MRCKA_HUMAN (241-552): 1.9e-37: 150: 16.30
+	Hs
		918873 RAB1A_HUMAN (2-196): 7e-80: 238: 28.71		RABE1_HUMAN (21-306): 2.47e-24: 109: 32.40
+	Hs
		914082 RB11A_HUMAN (3-196): 2.31e-76: 230: 27.27		RABE1_HUMAN (21-306): 2.47e-24: 109: 32.40
+	Hs
		1070480 RAB35_HUMAN (3-196): 3.21e-86: 254: 29.35		MRCKB_HUMAN (10-470): 3.13e-12: 72: 14.20
+	Hs
		318159 DIRA3_HUMAN (7-198): 1.85e-49: 161: 46.63		MRCKA_HUMAN (241-552): 1.9e-37: 150: 16.30
+	Hs
		894813 RAB8A_HUMAN (4-198): 3.1e-80: 239: 26.34		MYO5C_HUMAN (1-429): 2.21e-11: 69.3: 13.67
+	Hs
		148551 RAB13_HUMAN (4-197): 9.67e-80: 238: 29.00		CTRO_HUMAN (12-552): 8.68e-10: 63.9: 12.79
+	Hs
		148636 RAB1A_HUMAN (2-196): 7e-80: 238: 28.71		CTRO_HUMAN (12-552): 8.68e-10: 63.9: 12.79
+	Hs
		149274 RAB1B_HUMAN (2-196): 2.09e-79: 236: 28.86		CTRO_HUMAN (12-552): 8.68e-10: 63.9: 12.79
+	Hs
		914383 RB11A_HUMAN (3-196): 2.31e-76: 230: 27.27		MYO5C_HUMAN (1-429): 2.21e-11: 69.3: 13.67