HitPredict

Interactor 1: O77430 (O77430)
GEO01111p1 (HL01263p) (RH26825p) (SKP1-related A, isoform A) (SKP1-related A, isoform B) (SKP1-related A, isoform C) (SKP1-related A, isoform E) (SKP1-related A, isoform F) (SKP1-related A, isoform G) (SKPA)
Gene: SkpA

Interactor 2: FBSP1 (Q9V6L9)
F-box/SPRY domain-containing protein 1 (DFsn)
Gene: Fsn

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.914

The method score is based on:

Property Details
Experiments 24948796, 14605208, 15575970, 22036573, 38944040
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains F-box-like~Skp1
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0016567 - protein ubiquitination
GO:0019005 - SCF ubiquitin ligase complex
GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
and 1 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 162
Dm

1 255
+ Dm
+ Hs
+ Ce
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025