Protein: FBSP1
F-box/SPRY domain-containing protein 1 (F-box only protein 45) (hFbxo45)

Gene: FBSP1, FBXO45
Organism: Homo sapiens
Interactions: 89
UniProt ID: P0C2W1

Gene Ontology (top 5):
GO:0001764 - neuron migration
GO:0005576 - extracellular region
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

504729

SKP1
S-phase kinase-associated protein 1

7

6

Small-scale

0.964

High

504751

FBXW7
F-box/WD repeat-containing protein 7

5

13

Small-scale

0.929

High

504735

CUL1
Cullin-1

2

20

Small-scale

0.754

High

287853

MYCB2
E3 ubiquitin-protein ligase MYCBP2

7

16

Small-scale

0.749

High

504732

LG3BP
Galectin-3-binding protein

4

6

High-throughput

0.697

High

504770

HECD1
E3 ubiquitin-protein ligase HECTD1

1

16

High-throughput

0.691

High

504731

1433F
14-3-3 protein eta

3

17

High-throughput

0.662

High

504759

NMNA2
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2

3

1

Small-scale

0.650

High

504753

PAWR
PRKC apoptosis WT1 regulator protein

2

4

Small-scale

0.634

High

504720

STAT2
Signal transducer and activator of transcription 2

2

6

High-throughput

0.628

High

504772

CLC11
C-type lectin domain family 11 member A

2

3

High-throughput

0.628

High

504747

SPRY3
SPRY domain-containing protein 3

1

15

High-throughput

0.618

High

504709

EPHB2
Ephrin type-B receptor 2

2

16

High-throughput

0.618

High

504705

RO52
E3 ubiquitin-protein ligase TRIM21

1

12

High-throughput

0.618

High

504736

CUL3
Cullin-3

1

20

High-throughput

0.618

High

504704

CADH2
Cadherin-2

2

20

Small-scale

0.611

High

504760

CAD19
Cadherin-19

2

17

High-throughput

0.611

High

504775

HEY1
Hairy/enhancer-of-split related with YRPW motif protein 1

2

6

Small-scale

0.611

High

504706

IBP4
Insulin-like growth factor-binding protein 4

2

3

High-throughput

0.601

High

504726

1433G
14-3-3 protein gamma

2

17

High-throughput

0.601

High

504761

IL25
Interleukin-25

2

3

High-throughput

0.601

High

186688

P73
Tumor protein p73

1

6

Small-scale

0.561

High

221777

SNAI2
Zinc finger protein SNAI2

1

6

Small-scale

0.561

High

245577

ZEB2
Zinc finger E-box-binding homeobox 2

1

7

Small-scale

0.561

High

349752

SNAI1
Zinc finger protein SNAI1

1

9

Small-scale

0.561

High

504728

RBX1
E3 ubiquitin-protein ligase RBX1

1

6

Small-scale

0.561

High

504738

TWST1
Twist-related protein 1

1

3

Small-scale

0.561

High

504725

INHBE
Inhibin beta E chain

2

5

High-throughput

0.549

High

169230

CASQ2
Calsequestrin-2

1

7

High-throughput

0.536

High

336327

SVIL
Supervillin

1

6

High-throughput

0.536

High

336521

PIGN
GPI ethanolamine phosphate transferase 1

1

6

High-throughput

0.536

High

504701

TDGF1
Protein Cripto

1

3

High-throughput

0.536

High

504702

ARSB
Arylsulfatase B

1

6

High-throughput

0.536

High

504707

CTNA2
Catenin alpha-2

1

7

High-throughput

0.536

High

504708

GRN
Progranulin

1

3

High-throughput

0.536

High

504710

1433B
14-3-3 protein beta/alpha

1

17

High-throughput

0.536

High

504715

TCPZ
T-complex protein 1 subunit zeta

1

7

High-throughput

0.536

High

504716

MMP13
Collagenase 3

1

7

High-throughput

0.536

High

504717

TCPD
T-complex protein 1 subunit delta

1

7

High-throughput

0.536

High

504719

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

20

High-throughput

0.536

High

504721

PLK1
Serine/threonine-protein kinase PLK1

1

7

High-throughput

0.536

High

504723

TERA
Transitional endoplasmic reticulum ATPase

1

8

High-throughput

0.536

High

504730

TCPB
T-complex protein 1 subunit beta

1

10

High-throughput

0.536

High

504733

KIF1A
Kinesin-like protein KIF1A

1

20

High-throughput

0.536

High

504734

CETN1
Centrin-1

1

4

High-throughput

0.536

High

504737

EEA1
Early endosome antigen 1

1

14

High-throughput

0.536

High

504739

FAXC
Failed axon connections homolog

1

2

High-throughput

0.536

High

504741

FAT4
Protocadherin Fat 4

1

20

High-throughput

0.536

High

504748

PUM2
Pumilio homolog 2

1

6

High-throughput

0.536

High

504750

ARHG2
Rho guanine nucleotide exchange factor 2

1

17

High-throughput

0.536

High

504756

TCPH
T-complex protein 1 subunit eta

1

9

High-throughput

0.536

High

504757

TLR10
Toll-like receptor 10

1

2

High-throughput

0.536

High

504758

ABCA2
ATP-binding cassette sub-family A member 2

1

1

High-throughput

0.536

High

504765

NGRN
Neugrin

1

1

High-throughput

0.536

High

504768

PCD10
Protocadherin-10

1

20

High-throughput

0.536

High

504774

INSL6
Insulin-like peptide INSL6

1

3

High-throughput

0.536

High

504745

INLR1
Interferon lambda receptor 1

1

3

Small-scale

0.515

High

504742

RBPS2
RNA-binding protein with multiple splicing 2

1

0

High-throughput

0.513

High

155192

NCKP5
Nck-associated protein 5

1

14

High-throughput

0.489

High

275431

Z780A
Zinc finger protein 780A

1

2

High-throughput

0.489

High

504724

GDF10
Growth/differentiation factor 10

1

7

High-throughput

0.489

High

504744

ALPK2
Alpha-protein kinase 2

1

17

High-throughput

0.489

High

504746

PGLT1
Protein O-glucosyltransferase 1

1

4

High-throughput

0.489

High

504749

SHRM3
Protein Shroom3

1

15

High-throughput

0.489

High

395364

ESR1
Estrogen receptor

1

11

Small-scale

0.479

High

504711

CTNB1
Catenin beta-1

1

13

Small-scale

0.479

High

504712

NOS2
Nitric oxide synthase, inducible

1

7

High-throughput

0.479

High

504713

RFC4
Replication factor C subunit 4

1

4

High-throughput

0.479

High

504714

ZEB1
Zinc finger E-box-binding homeobox 1

1

7

Small-scale

0.479

High

504718

MECP2
Methyl-CpG-binding protein 2

1

3

High-throughput

0.479

High

504727

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

20

High-throughput

0.479

High

504740

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

1

3

High-throughput

0.479

High

504743

UBP49
Ubiquitin carboxyl-terminal hydrolase 49

1

12

Small-scale

0.479

High

504763

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

504764

MYO10
Unconventional myosin-X

1

12

Small-scale

0.479

High

504766

HEYL
Hairy/enhancer-of-split related with YRPW motif-like protein

1

6

Small-scale

0.479

High

504769

HEY2
Hairy/enhancer-of-split related with YRPW motif protein 2

1

6

Small-scale

0.479

High

504771

FAF1
FAS-associated factor 1

1

8

High-throughput

0.479

High

504773

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

20

Small-scale

0.479

High

504762

GGNB2
Gametogenetin-binding protein 2

1

0

Small-scale

0.458

High

504767

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

0

Small-scale

0.458

High

504700

CALM1
Calmodulin-1

1

1

High-throughput

0.445

High

504703

VINC
Vinculin

1

14

High-throughput

0.445

High

504752

ESPB1
Epididymal sperm-binding protein 1

1

6

High-throughput

0.445

High

504755

Q96KY9
CDH19 protein

1

20

High-throughput

0.445

High

105182

APRIO
Alternative prion protein

1

2

Small-scale

0.439

High

66115

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.279

Low

504722

GALC
Galactocerebrosidase

1

0

High-throughput

0.249

Low

504754

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025