Interactor 1: ELP1 (O95163)
Elongator complex protein 1 (ELP1) (IkappaB kinase complex-associated protein) (IKK complex-associated protein) (p150)
Gene: ELP1

Interactor 2: ELP3 (Q9H9T3)
Elongator complex protein 3 (hELP3) (EC 2.3.1.311) (tRNA uridine(34) acetyltransferase)
Gene: ELP3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 11714725, 33961781, 19834596, 11818576, 26261306, 36617428, 18303054, 19185337, 22854966
Identification Methods biochemical, affinity chromatography technology, pull down, mass spectrometry studies of complexes, anti tag coimmunoprecipitation, chromatography technology, anti bait coimmunoprecipitation
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains IKI3~Radical_SAM
Common GO terms GO:0000049 - tRNA binding
GO:0002098 - tRNA wobble uridine modification
GO:0002926 - tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 3 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1332
Hs

1 547
+ Mm
+ Dm
+ Sc
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024