HitPredict

Interactor 1: VAMP5 (O95183)
Vesicle-associated membrane protein 5 (VAMP-5) (Myobrevin)
Gene: VAMP5

Interactor 2: GOSR1 (O95249)
Golgi SNAP receptor complex member 1 (28 kDa Golgi SNARE protein) (28 kDa cis-Golgi SNARE p28) (GOS-28)
Gene: GOSR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	30833792, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Synaptobrevin~V-SNARE_C
Common GO terms	GO:0005794 - Golgi apparatus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 116 Hs			1 250
+	Hs
		103893 VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00		G5E9T8_HUMAN (11-250): 2.73e-108: 314: 100.00
+	Hs
		261623 VAMP4_HUMAN (3-73): 1.13e-25: 95.3: 29.58		GOSR1_HUMAN (1-250): 6.41e-114: 328: 100.00
+	Hs
		263124 SC22B_HUMAN (2-86): 2.38e-23: 91.1: 17.65		GOSR1_HUMAN (1-250): 6.41e-114: 328: 100.00
+	Hs
		309587 VAMP3_HUMAN (2-72): 2.01e-24: 90.7: 38.03		GOSR1_HUMAN (1-250): 6.41e-114: 328: 100.00
+	Hs
		92386 VAMP4_HUMAN (3-73): 1.13e-25: 95.3: 29.58		E9PCW1_HUMAN (1-250): 5.28e-111: 320: 99.20
+	Hs
		92387 SC22B_HUMAN (2-86): 2.38e-23: 91.1: 17.65		E9PCW1_HUMAN (1-250): 5.28e-111: 320: 99.20
+	Dm
		1178120 Q7JYX5_DROME (4-96): 1.36e-32: 114: 31.18		GOSR1_DROME (5-250): 8.4e-72: 221: 45.75
+	Dm
		577242 SYB_DROME (2-88): 9.74e-30: 105: 39.08		GOSR1_DROME (5-250): 8.4e-72: 221: 45.75
+	Sc
		753377 NYV1_YEAST (9-81): 2.24e-21: 86.9: 21.92		GOSR1_YEAST (36-246): 6.41e-56: 180: 24.06