HitPredict

Interactor 1: KLHL2 (O95198)
Kelch-like protein 2 (Actin-binding protein Mayven)
Gene: KLHL2

Interactor 2: SCYL1 (Q96KG9)
N-terminal kinase-like protein (Coated vesicle-associated kinase of 90 kDa) (SCY1-like protein 1) (Telomerase regulation-associated protein) (Telomerase transcriptional element-interacting factor) (Teratoma-associated tyrosine kinase)
Gene: SCYL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 593 Hs			1 808
+	Hs
		1120803 KLH12_HUMAN (30-592): 1.63e-174: 508: 41.70		SCYL1_HUMAN (1-808): 0: 621: 100.00
+	Hs
		159127 KLHL2_HUMAN (1-593): 0: 574: 100.00		CSKP_HUMAN (7-686): 4.5e-119: 383: 13.70
+	Hs
		1047590 KEAP1_HUMAN (146-593): 8.68e-52: 189: 23.88		CDK13_HUMAN (9-735): 3.15e-112: 375: 12.76
+	Hs
		282290 KLH20_HUMAN (494-593): 2.37e-25: 112: 45.00		CDKL5_HUMAN (13-772): 5.5e-113: 368: 12.78