HitPredict

Interactor 1: RCBT2 (O95199)
RCC1 and BTB domain-containing protein 2 (Chromosome condensation 1-like) (CHC1-L) (RCC1-like G exchanging factor) (Regulator of chromosome condensation and BTB domain-containing protein 2)
Gene: RCBTB2

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	35563538, 19256485
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	BTB~Cullin
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 551 Hs			1 768
+	Hs
		1041654 HERC1_HUMAN (2-222): 1.54e-58: 213: 26.96		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		578433 RCC1_HUMAN (12-356): 2.52e-61: 209: 20.00		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042791 HERC5_HUMAN (2-220): 5.92e-56: 204: 22.59		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042110 NEK9_HUMAN (58-370): 1.11e-51: 192: 22.52		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042070 RCBT1_HUMAN (1-183): 1.26e-44: 167: 24.23		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1043285 HERC5_HUMAN (2-220): 5.92e-56: 204: 22.59		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043115 NEK9_HUMAN (58-370): 1.11e-51: 192: 22.52		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043636 HERC5_HUMAN (2-220): 5.92e-56: 204: 22.59		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		1043624 RCC2_HUMAN (170-428): 2.74e-34: 137: 20.59		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		1041254 HERC5_HUMAN (2-220): 5.92e-56: 204: 22.59		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		1041493 HERC5_HUMAN (2-220): 5.92e-56: 204: 22.59		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		1041097 RCBT1_HUMAN (1-183): 1.26e-44: 167: 24.23		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		1041402 RCBT1_HUMAN (1-183): 1.26e-44: 167: 24.23		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		1274076 HERC5_HUMAN (2-220): 5.92e-56: 204: 22.59		CUL5_HUMAN (25-768): 0: 597: 23.77
+	Hs
		1242534 RCBT1_HUMAN (1-183): 1.26e-44: 167: 24.23		CUL5_HUMAN (25-768): 0: 597: 23.77