HitPredict

Interactor 1: KI20A (O95235)
Kinesin-like protein KIF20A (GG10_2) (Mitotic kinesin-like protein 2) (MKlp2) (Rab6-interacting kinesin-like protein) (Rabkinesin-6)
Gene: KIF20A

Interactor 2: BRCA1 (P38398)
Breast cancer type 1 susceptibility protein (EC 2.3.2.27) (RING finger protein 53) (RING-type E3 ubiquitin transferase BRCA1)
Gene: BRCA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25184681, 26831064
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 890 Hs			1 1863
+	Hs
		749392 KIF23_HUMAN (60-772): 3.56e-103: 344: 25.21		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Hs
		231466 KIF1B_HUMAN (64-229): 1.47e-33: 142: 19.89		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Hs
		702858 KINH_HUMAN (61-252): 1.28e-31: 135: 25.13		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Hs
		749267 KIF11_HUMAN (299-644): 1.1e-28: 125: 30.99		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Hs
		749791 KI20B_HUMAN (494-852): 1.68e-09: 64.1: 13.02		BRCA1_HUMAN (1-1863): 0: 1570: 100.00
+	Hs
		308371 KI20A_HUMAN (1-890): 0: 562: 100.00		TRI27_HUMAN (13-390): 9.61e-69: 243: 11.74
+	Hs
		309041 KI20A_HUMAN (1-890): 0: 562: 100.00		TRIM5_HUMAN (10-339): 1.37e-63: 227: 13.27
+	Hs
		309042 KI20A_HUMAN (1-890): 0: 562: 100.00		TRIM4_HUMAN (15-377): 1.5e-62: 225: 11.52
+	Hs
		309040 KI20A_HUMAN (1-890): 0: 562: 100.00		TRIM7_HUMAN (19-291): 1.53e-44: 172: 12.16
+	Hs
		536789 KIF23_HUMAN (60-772): 3.56e-103: 344: 25.21		TRI27_HUMAN (13-390): 9.61e-69: 243: 11.74
+	Hs
		1066256 KIF14_HUMAN (7-225): 1.5e-30: 132: 16.90		TRI68_HUMAN (12-388): 1.67e-74: 259: 11.31
+	Hs
		536804 KIF1A_HUMAN (64-229): 2e-34: 144: 18.18		TRI27_HUMAN (13-390): 9.61e-69: 243: 11.74
+	Hs
		536838 KIF14_HUMAN (7-225): 1.5e-30: 132: 16.90		TRI27_HUMAN (13-390): 9.61e-69: 243: 11.74
+	Hs
		1066732 KIF14_HUMAN (7-225): 1.5e-30: 132: 16.90		TRI39_HUMAN (15-389): 8.42e-67: 238: 13.19
+	Hs
		855729 KIF11_HUMAN (299-644): 1.1e-28: 125: 30.99		TRIM6_HUMAN (10-377): 5.59e-67: 237: 13.54
+	Hs
		1066647 KIF14_HUMAN (7-225): 1.5e-30: 132: 16.90		TRIM5_HUMAN (10-339): 1.37e-63: 227: 13.27
+	Hs
		1066648 KIF14_HUMAN (7-225): 1.5e-30: 132: 16.90		TRIM4_HUMAN (15-377): 1.5e-62: 225: 11.52