HitPredict

Interactor 1: TRI16 (O95361)
Tripartite motif-containing protein 16 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM16) (Estrogen-responsive B box protein)
Gene: TRIM16

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	35156780
Identification Methods	protein complementation assay, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 564 Hs			1 1480
+	Hs
		528519 RO52_HUMAN (51-553): 2.72e-144: 426: 18.61		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528467 TRI27_HUMAN (51-548): 1.38e-142: 423: 20.47		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529691 TRIM5_HUMAN (43-548): 1.13e-121: 369: 15.95		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529198 TR16L_HUMAN (217-564): 5.91e-105: 321: 97.41		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529108 TRI25_HUMAN (57-548): 3.06e-100: 318: 23.73		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529096 TRI29_HUMAN (73-285): 4.05e-31: 129: 35.51		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529591 ERMAP_HUMAN (375-523): 4.88e-10: 63.9: 30.72		CFTR_HUMAN (1-1480): 0: 1031: 100.00