HitPredict

Interactor 1: FLIC (P06179)
Flagellin (Phase 1-I flagellin)
Gene: FLIC

Interactor 2: FLIS (P26609)
Flagellar secretion chaperone FliS
Gene: FLIS

Species: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.80	0.723

Property	Details
Experiments	12620624, 16806204
Identification Methods	two hybrid, affinity technology, pull down, isothermal titration calorimetry, circular dichroism
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Flagellin_C~FliS, Flagellin_N~FliS
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 495 Se			1 135
+	Hp
		202569 FLAB_HELPY (1-495): 1.58e-97: 305: 25.24		O25448_HELPY (1-125): 5.73e-42: 136: 35.20
+	Hp
		202565 FLAA_HELPY (1-494): 4.93e-95: 298: 25.34		O25448_HELPY (1-125): 5.73e-42: 136: 35.20
+	Aa
		266359 FLAA_AQUAE (1-495): 8.73e-86: 275: 27.51		O67806_AQUAE (11-128): 2.26e-28: 102: 27.87
+	Tp
		311845 FLAB2_TREPA (3-237): 5.98e-47: 166: 29.27		O83913_TREPA (2-130): 2.88e-37: 125: 31.62
+	Tp
		311844 FLAB1_TREPA (3-272): 1.61e-45: 162: 26.39		O83913_TREPA (2-130): 2.88e-37: 125: 31.62
+	Tp
		311846 FLAB3_TREPA (3-236): 5.92e-45: 160: 31.54		O83913_TREPA (2-130): 2.88e-37: 125: 31.62
+	Cj
		943171 FLA1_CAMJE (391-495): 4.36e-21: 98.4: 36.19		Q0PAW7_CAMJE (1-125): 3.77e-38: 127: 32.80
+	Cj
		943177 FLB1_CAMJE (391-495): 3.67e-21: 98.4: 33.33		Q0PAW7_CAMJE (1-125): 3.77e-38: 127: 32.80