HitPredict

Interactor 1: ARI2 (O95376)
E3 ubiquitin-protein ligase ARIH2 (ARI-2) (Protein ariadne-2 homolog) (EC 2.3.2.31) (RING-type E3 ubiquitin transferase ARIH2) (Triad1 protein)
Gene: ARIH2

Interactor 2: K1C10 (P13645)
Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)
Gene: KRT10

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31253590
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 493 Hs			1 584
+	Hs
		312438 ARI2_HUMAN (1-493): 0: 546: 100.00		K1C14_HUMAN (144-457): 1.33e-144: 427: 69.43
+	Hs
		312498 ARI2_HUMAN (1-493): 0: 546: 100.00		K1C9_HUMAN (141-455): 3.9e-117: 362: 57.14
+	Hs
		312606 ARI2_HUMAN (1-493): 0: 546: 100.00		K2C72_HUMAN (36-533): 1.34e-75: 250: 22.96
+	Hs
		531410 RNF31_HUMAN (104-374): 5.18e-60: 215: 19.72		K1C10_HUMAN (141-454): 1.05e-147: 439: 100.00
+	Hs
		359399 RNF31_HUMAN (104-374): 5.18e-60: 215: 19.72		K1C14_HUMAN (144-457): 1.33e-144: 427: 69.43
+	Hs
		445103 RNF31_HUMAN (104-374): 5.18e-60: 215: 19.72		K1C16_HUMAN (142-456): 9.28e-143: 423: 67.62
+	Hs
		226395 PRKN_HUMAN (113-330): 7.77e-52: 184: 22.93		K1C10_HUMAN (141-454): 1.05e-147: 439: 100.00
+	Hs
		444450 RNF31_HUMAN (104-374): 5.18e-60: 215: 19.72		K1C19_HUMAN (140-456): 2.13e-136: 404: 65.30
+	Hs
		226212 PRKN_HUMAN (113-330): 7.77e-52: 184: 22.93		K1C14_HUMAN (144-457): 1.33e-144: 427: 69.43
+	Hs
		226396 PRKN_HUMAN (113-330): 7.77e-52: 184: 22.93		K1C13_HUMAN (135-471): 4.47e-144: 425: 63.50
+	Hs
		226314 PRKN_HUMAN (113-330): 7.77e-52: 184: 22.93		K1C16_HUMAN (142-456): 9.28e-143: 423: 67.62
+	Hs
		226480 PRKN_HUMAN (113-330): 7.77e-52: 184: 22.93		K1C15_HUMAN (130-462): 8.09e-141: 417: 65.47
+	Hs
		226312 PRKN_HUMAN (113-330): 7.77e-52: 184: 22.93		K1C19_HUMAN (140-456): 2.13e-136: 404: 65.30
+	Hs
		724123 RNF31_HUMAN (104-374): 5.18e-60: 215: 19.72		K1C9_HUMAN (141-455): 3.9e-117: 362: 57.14
+	Hs
		226676 PRKN_HUMAN (113-330): 7.77e-52: 184: 22.93		K1C9_HUMAN (141-455): 3.9e-117: 362: 57.14
+	Hs
		359526 RNF31_HUMAN (104-374): 5.18e-60: 215: 19.72		K2C6A_HUMAN (2-463): 1.75e-72: 244: 25.05
+	Hs
		531618 RNF31_HUMAN (104-374): 5.18e-60: 215: 19.72		K2C5_HUMAN (4-463): 5.63e-70: 238: 23.14
+	Hs
		226160 PRKN_HUMAN (113-330): 7.77e-52: 184: 22.93		K2C75_HUMAN (4-543): 1.61e-80: 265: 26.42
+	Hs
		226231 PRKN_HUMAN (113-330): 7.77e-52: 184: 22.93		K2C6B_HUMAN (2-463): 5.61e-74: 248: 24.84
+	Hs
		226397 PRKN_HUMAN (113-330): 7.77e-52: 184: 22.93		K2C5_HUMAN (4-463): 5.63e-70: 238: 23.14