HitPredict

Interactor 1: M3K6 (O95382)
Mitogen-activated protein kinase kinase kinase 6 (EC 2.7.11.25) (Apoptosis signal-regulating kinase 2)
Gene: MAP3K6

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19935702
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1288 Hs			1 246
+	Hs
		312790 M3K6_HUMAN (1-1288): 0: 1354: 99.38		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		312792 M3K6_HUMAN (1-1288): 0: 1354: 99.38		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		312777 M3K6_HUMAN (1-1288): 0: 1354: 99.38		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		312789 M3K6_HUMAN (1-1288): 0: 1354: 99.38		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		312793 M3K6_HUMAN (1-1288): 0: 1354: 99.38		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		312781 M3K6_HUMAN (1-1288): 0: 1354: 99.38		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62
+	Hs
		909955 M3K5_HUMAN (2-1282): 0: 1194: 44.40		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		683661 M3K5_HUMAN (2-1282): 0: 1194: 44.40		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		927451 M3K5_HUMAN (2-1282): 0: 1194: 44.40		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		909709 M3K15_HUMAN (2-1278): 0: 1186: 43.56		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		927194 M3K15_HUMAN (2-1278): 0: 1186: 43.56		1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60
+	Hs
		647219 M3K5_HUMAN (2-1282): 0: 1194: 44.40		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		905034 M3K5_HUMAN (2-1282): 0: 1194: 44.40		1433G_HUMAN (3-246): 1.91e-109: 317: 75.40
+	Hs
		982422 M3K5_HUMAN (2-1282): 0: 1194: 44.40		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		982174 M3K15_HUMAN (2-1278): 0: 1186: 43.56		1433F_HUMAN (4-244): 2.7e-107: 311: 75.51
+	Hs
		684290 M3K5_HUMAN (2-1282): 0: 1194: 44.40		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62
+	Hs
		159186 CSKP_HUMAN (648-1288): 4.4e-132: 430: 16.86		1433E_HUMAN (3-243): 4.39e-144: 405: 65.43
+	Hs
		683485 MARK2_HUMAN (596-1261): 5.09e-129: 418: 14.12		1433B_HUMAN (1-246): 3.48e-144: 404: 100.00
+	Hs
		647041 MARK2_HUMAN (596-1261): 5.09e-129: 418: 14.12		1433T_HUMAN (3-244): 3.24e-127: 361: 81.82
+	Hs
		684157 MARK2_HUMAN (596-1261): 5.09e-129: 418: 14.12		1433S_HUMAN (3-239): 3.38e-100: 293: 68.62