Protein: SMAD1
Mothers against decapentaplegic homolog 1 (MAD homolog 1) (Mothers against DPP homolog 1) (Dwarfin-A) (Dwf-A) (Mothers-against-DPP-related 1) (Mad-related protein 1) (mMad1) (SMAD family member 1) (SMAD 1) (Smad1)

Gene: SMAD1
Organism: Mus musculus
Interactions: 40
UniProt ID: P70340

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1000222

SMAD4
Mothers against decapentaplegic homolog 4

2

19

Small-scale

0.737

High

1000237

SMUF1
E3 ubiquitin-protein ligase SMURF1

3

20

Small-scale

0.642

High

1000228

M3K7
Mitogen-activated protein kinase kinase kinase 7

2

8

Small-scale

0.624

High

1000243

SMAD9
Mothers against decapentaplegic homolog 9

1

19

Small-scale

0.618

High

1000244

UCHL3
Ubiquitin carboxyl-terminal hydrolase isozyme L3

2

7

Small-scale

0.584

High

999935

HXD13
Homeobox protein Hox-D13

1

18

Small-scale

0.573

High

1000224

GATA4
Transcription factor GATA-4

1

8

Small-scale

0.561

High

59025

SMUF2
E3 ubiquitin-protein ligase SMURF2

2

20

Small-scale

0.533

High

1000233

ZNF8
Zinc finger protein 8

1

4

Small-scale

0.527

High

60003

ARI1A
AT-rich interactive domain-containing protein 1A

1

15

Small-scale

0.515

High

1000239

TBX20
T-box transcription factor TBX20

1

4

Small-scale

0.515

High

1000229

HXA13
Homeobox protein Hox-A13

1

19

Small-scale

0.508

High

148068

PAR3
Proteinase-activated receptor 3

1

3

Small-scale

0.501

High

900698

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

17

Small-scale

0.501

High

1000231

ERBIN
Erbin

1

10

Small-scale

0.501

High

1000242

KAT2B
Histone acetyltransferase KAT2B

1

20

Small-scale

0.501

High

1000238

SUV92
Histone-lysine N-methyltransferase SUV39H2

1

6

Small-scale

0.481

High

1000245

ZEB2
Zinc finger E-box-binding homeobox 2

1

14

High-throughput

0.481

High

59137

PRD16
Histone-lysine N-methyltransferase PRDM16

1

13

Small-scale

0.479

High

312779

PRS6A
26S proteasome regulatory subunit 6A

1

2

Small-scale

0.479

High

313422

KLF10
Krueppel-like factor 10

1

11

Small-scale

0.479

High

465916

CO3A1

1

16

Small-scale

0.479

High

518505

MYOD1
Myoblast determination protein 1

1

4

Small-scale

0.479

High

879691

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

14

Small-scale

0.479

High

896215

MXI1
Max-interacting protein 1

1

12

Small-scale

0.479

High

1000220

CXB6
Gap junction beta-6 protein

1

2

Small-scale

0.479

High

1000221

BACH1
Transcription regulator protein BACH1

1

7

Small-scale

0.479

High

1000223

BTG2
Protein BTG2

1

12

Small-scale

0.479

High

1000225

RUNX2
Runt-related transcription factor 2

1

16

Small-scale

0.479

High

1000226

SF3B2
Splicing factor 3B subunit 2

1

5

Small-scale

0.479

High

1000227

TAPT1
Transmembrane anterior posterior transformation protein 1

1

1

Small-scale

0.479

High

1000230

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

1

3

Small-scale

0.479

High

1000234

Q8BTS0
Probable ATP-dependent RNA helicase DDX5

1

10

Small-scale

0.479

High

1000236

ZMYM2
Zinc finger MYM-type protein 2

1

5

Small-scale

0.479

High

1000240

4ET
Eukaryotic translation initiation factor 4E transporter

1

4

Small-scale

0.479

High

505009

KGP1
cGMP-dependent protein kinase 1

1

14

Small-scale

0.445

High

1000241

GTF2I
General transcription factor II-I

1

3

Small-scale

0.445

High

312006

CO5A1

1

16

Small-scale

0.437

High

1000232

ZFY16
Zinc finger FYVE domain-containing protein 16

1

12

Small-scale

0.437

High

1000235

PEX6
Peroxisomal ATPase PEX6

1

5

Small-scale

0.437

High


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Last updated: 11Aug2025