HitPredict

Interactor 1: ZFYV9 (O95405)
Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation)
Gene: ZFYVE9

Interactor 2: PGFRA (P16234)
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
Gene: PDGFRA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1425 Hs			1 1089
+	Hs
		557174 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		PGFRA_HUMAN (1-1089): 0: 817: 100.00
+	Hs
		313542 ZFYV9_HUMAN (1-1425): 0: 1620: 100.00		NTRK2_HUMAN (48-776): 2.93e-51: 197: 14.04
+	Hs
		313504 ZFYV9_HUMAN (1-1425): 0: 1620: 100.00		FGFR2_HUMAN (6-339): 9.02e-49: 189: 14.90
+	Hs
		452449 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		PGFRB_HUMAN (29-1089): 0: 650: 43.33
+	Hs
		313505 ZFYV9_HUMAN (1-1425): 0: 1620: 100.00		FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36
+	Hs
		313488 ZFYV9_HUMAN (1-1425): 0: 1620: 100.00		CSF1R_HUMAN (212-602): 7.71e-15: 81.4: 10.59
+	Hs
		313492 ZFYV9_HUMAN (1-1425): 0: 1620: 100.00		FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71
+	Hs
		601538 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		FGFR2_HUMAN (6-339): 9.02e-49: 189: 14.90
+	Hs
		608024 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36
+	Hs
		508079 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71
+	Hs
		159875 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		PGFRA_HUMAN (1-1089): 0: 817: 100.00
+	Hs
		452448 FGD6_HUMAN (29-866): 1.74e-100: 355: 14.78		PGFRB_HUMAN (29-1089): 0: 650: 43.33
+	Hs
		159856 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		PGFRB_HUMAN (29-1089): 0: 650: 43.33
+	Hs
		609293 EEA1_HUMAN (2-758): 9.63e-69: 257: 12.42		FGFR3_HUMAN (745-969): 1.84e-76: 270: 40.74
+	Hs
		601507 MTMR3_HUMAN (196-777): 2.87e-71: 263: 13.18		FGFR2_HUMAN (6-339): 9.02e-49: 189: 14.90
+	Hs
		159885 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		FGFR2_HUMAN (6-339): 9.02e-49: 189: 14.90
+	Hs
		159848 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		RET_HUMAN (573-690): 7.85e-22: 104: 43.22
+	Hs
		159888 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36
+	Hs
		159845 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		CSF1R_HUMAN (212-602): 7.71e-15: 81.4: 10.59
+	Hs
		159864 HGS_HUMAN (654-976): 7.98e-53: 202: 19.55		FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71