Protein: AT12A
Potassium-transporting ATPase alpha chain 2 (HK alpha 2) (Non-gastric H(+)/K(+) ATPase subunit alpha) (EC 7.2.2.19) (Non-gastric Na(+)/K(+) ATPase subunit alpha) (EC 7.2.2.13) (Proton pump) (Sodium pump)

Gene: AT12A, ATP12A
Organism: Homo sapiens
Interactions: 177
UniProt ID: P54707

Gene Ontology (top 5):
GO:0005391 - P-type sodium:potassium-exchanging transporter activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005889 - potassium:proton exchanging ATPase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

871888

AT1B3
Sodium/potassium-transporting ATPase subunit beta-3

3

16

High-throughput

0.861

High

393427

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

16

High-throughput

0.691

High

871961

FXYD6
FXYD domain-containing ion transport regulator 6

1

2

High-throughput

0.691

High

199872

SPIT2
Kunitz-type protease inhibitor 2

3

4

High-throughput

0.667

High

674839

AGTR1
Type-1 angiotensin II receptor

3

20

High-throughput

0.667

High

793073

PF2R
Prostaglandin F2-alpha receptor

3

9

High-throughput

0.667

High

871895

TNR9
Tumor necrosis factor receptor superfamily member 9

3

10

High-throughput

0.667

High

871896

CLM6
CMRF35-like molecule 6

3

4

High-throughput

0.667

High

871930

TARG1
Trafficking regulator of GLUT4 1

3

5

High-throughput

0.667

High

871907

P2Y14
P2Y purinoceptor 14

3

20

High-throughput

0.657

High

252743

FCG3B
Low affinity immunoglobulin gamma Fc region receptor III-B

3

1

High-throughput

0.656

High

871901

NAR3
Ecto-ADP-ribosyltransferase 3

3

1

High-throughput

0.656

High

212285

ITM2A
Integral membrane protein 2A

2

7

High-throughput

0.628

High

598721

S1PR1
Sphingosine 1-phosphate receptor 1

2

20

High-throughput

0.628

High

611187

GTR5
Solute carrier family 2, facilitated glucose transporter member 5

2

7

High-throughput

0.628

High

626508

FPR2
N-formyl peptide receptor 2

2

20

High-throughput

0.628

High

626735

NK1R
Substance-P receptor

2

14

High-throughput

0.628

High

674783

GRPR
Gastrin-releasing peptide receptor

2

17

High-throughput

0.628

High

801592

S15A1
Solute carrier family 15 member 1

2

5

High-throughput

0.628

High

871913

AGK
Acylglycerol kinase, mitochondrial

2

1

High-throughput

0.628

High

871949

MRAP2
Melanocortin-2 receptor accessory protein 2

2

1

High-throughput

0.628

High

871967

PACC1
Proton-activated chloride channel

2

1

High-throughput

0.628

High

871974

C5AR2
C5a anaphylatoxin chemotactic receptor 2

2

20

High-throughput

0.628

High

871977

CLC2D
C-type lectin domain family 2 member D

2

8

High-throughput

0.628

High

871894

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

2

6

High-throughput

0.611

High

154086

H17B6
17-beta-hydroxysteroid dehydrogenase type 6

3

4

High-throughput

0.609

High

871891

DLK1
Protein delta homolog 1

3

2

High-throughput

0.609

High

871899

SLAF1
Signaling lymphocytic activation molecule

3

6

High-throughput

0.609

High

871908

DHC24
Delta(24)-sterol reductase

3

3

High-throughput

0.609

High

871919

SUSD4
Sushi domain-containing protein 4

3

1

High-throughput

0.609

High

871925

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

3

3

High-throughput

0.609

High

871926

RETR3
Reticulophagy regulator 3

3

1

High-throughput

0.609

High

871948

WBP1
WW domain-binding protein 1

3

1

High-throughput

0.609

High

871987

SRPRB
Signal recognition particle receptor subunit beta

3

10

High-throughput

0.609

High

871945

GLMP
Glycosylated lysosomal membrane protein

2

0

High-throughput

0.602

High

871953

FEZ1
Fasciculation and elongation protein zeta-1

2

0

High-throughput

0.602

High

871917

SYRM
Probable arginine--tRNA ligase, mitochondrial

2

0

High-throughput

0.585

High

49136

TM223
Transmembrane protein 223

2

1

High-throughput

0.574

High

871906

TMED2
Transmembrane emp24 domain-containing protein 2

2

5

High-throughput

0.574

High

871936

SPX3
Sugar phosphate exchanger 3

2

2

High-throughput

0.574

High

871941

F174A
Membrane protein FAM174A

2

2

High-throughput

0.574

High

871983

PRG3
Proteoglycan 3

2

1

High-throughput

0.574

High

354380

HLAB
HLA class I histocompatibility antigen, B alpha chain

2

4

High-throughput

0.552

High

444698

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

6

High-throughput

0.541

High

125988

UPK1A
Uroplakin-1a

1

10

High-throughput

0.536

High

131886

UPK2
Uroplakin-2

1

2

High-throughput

0.536

High

134372

ACKR2
Atypical chemokine receptor 2

1

15

High-throughput

0.536

High

155894

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

10

High-throughput

0.536

High

156808

FFAR1
Free fatty acid receptor 1

1

20

High-throughput

0.536

High

168177

PLCB
1-acyl-sn-glycerol-3-phosphate acyltransferase beta

1

12

High-throughput

0.536

High

171966

GP182
G-protein coupled receptor 182

1

20

High-throughput

0.536

High

196754

CYB5B
Cytochrome b5 type B

1

4

High-throughput

0.536

High

198091

MTLR
Motilin receptor

1

20

High-throughput

0.536

High

206582

S26A4
Pendrin

1

2

High-throughput

0.536

High

208450

OX2R
Orexin receptor type 2

1

13

High-throughput

0.536

High

215811

G6PT1
Glucose-6-phosphate exchanger SLC37A4

1

2

High-throughput

0.536

High

217305

TYOBP
TYRO protein tyrosine kinase-binding protein

1

1

High-throughput

0.536

High

235238

NPHN
Nephrin

1

1

High-throughput

0.536

High

328317

S1PR4
Sphingosine 1-phosphate receptor 4

1

20

High-throughput

0.536

High

353054

IL2RA
Interleukin-2 receptor subunit alpha

1

1

High-throughput

0.536

High

598929

FPR1
fMet-Leu-Phe receptor

1

20

High-throughput

0.536

High

600754

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

20

High-throughput

0.536

High

626775

PTAFR
Platelet-activating factor receptor

1

20

High-throughput

0.536

High

644667

NKG2C
NKG2-C type II integral membrane protein

1

9

High-throughput

0.536

High

666302

NK3R
Neuromedin-K receptor

1

15

High-throughput

0.536

High

677584

NTR1
Neurotensin receptor type 1

1

16

High-throughput

0.536

High

686274

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

6

High-throughput

0.536

High

686624

CCR1
C-C chemokine receptor type 1

1

18

High-throughput

0.536

High

723285

APJ
Apelin receptor

1

19

High-throughput

0.536

High

770217

GPV
Platelet glycoprotein V

1

10

High-throughput

0.536

High

781050

OPRX
Nociceptin receptor

1

16

High-throughput

0.536

High

782415

P2RY2
P2Y purinoceptor 2

1

20

High-throughput

0.536

High

783627

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

6

High-throughput

0.536

High

813931

GPR12
G-protein coupled receptor 12

1

18

High-throughput

0.536

High

814241

GLR
Glucagon receptor

1

6

High-throughput

0.536

High

849659

CCR6
C-C chemokine receptor type 6

1

19

High-throughput

0.536

High

856594

EFNA5
Ephrin-A5

1

2

High-throughput

0.536

High

871889

PAR2
Proteinase-activated receptor 2

1

20

High-throughput

0.536

High

871890

X3CL1
Fractalkine

1

1

High-throughput

0.536

High

871893

S25A3
Solute carrier family 25 member 3

1

5

High-throughput

0.536

High

871898

KLRB1
Killer cell lectin-like receptor subfamily B member 1

1

9

High-throughput

0.536

High

871900

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

20

High-throughput

0.536

High

871904

NAA30
N-alpha-acetyltransferase 30

1

1

High-throughput

0.536

High

871905

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

4

High-throughput

0.536

High

871909

KS6A1
Ribosomal protein S6 kinase alpha-1

1

4

High-throughput

0.536

High

871910

CD226
CD226 antigen

1

6

High-throughput

0.536

High

871924

PCAT2
Lysophosphatidylcholine acyltransferase 2

1

10

High-throughput

0.536

High

871927

P2RY8
P2Y purinoceptor 8

1

20

High-throughput

0.536

High

871928

INLR1
Interferon lambda receptor 1

1

1

High-throughput

0.536

High

871931

S22AF
Solute carrier family 22 member 15

1

2

High-throughput

0.536

High

871934

KC1AL
Casein kinase I isoform alpha-like

1

5

High-throughput

0.536

High

871935

RN149
E3 ubiquitin-protein ligase RNF149

1

5

High-throughput

0.536

High

871942

SPP2B
Signal peptide peptidase-like 2B

1

5

High-throughput

0.536

High

871944

RAB2B
Ras-related protein Rab-2B

1

9

High-throughput

0.536

High

871954

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

1

High-throughput

0.536

High

871957

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

7

High-throughput

0.536

High

871959

GPR88
G protein-coupled receptor 88

1

1

High-throughput

0.536

High

871960

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

3

High-throughput

0.536

High

871962

TSN10
Tetraspanin-10

1

9

High-throughput

0.536

High

871963

CXL16
C-X-C motif chemokine 16

1

1

High-throughput

0.536

High

871968

CHODL
Chondrolectin

1

3

High-throughput

0.536

High

871969

TREM1
Triggering receptor expressed on myeloid cells 1

1

3

High-throughput

0.536

High

871970

KCMB3
Calcium-activated potassium channel subunit beta-3

1

2

High-throughput

0.536

High

871972

GPR84
G-protein coupled receptor 84

1

3

High-throughput

0.536

High

871973

KLH11
Kelch-like protein 11

1

1

High-throughput

0.536

High

871975

HCST
Hematopoietic cell signal transducer

1

1

High-throughput

0.536

High

871980

PRND
Prion-like protein doppel

1

1

High-throughput

0.536

High

871985

RN115
E3 ubiquitin-protein ligase RNF115

1

4

High-throughput

0.536

High

871986

PCDG7
Protocadherin gamma-A7

1

8

High-throughput

0.536

High

614283

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

0

High-throughput

0.518

High

871971

ACKR4
Atypical chemokine receptor 4

1

16

High-throughput

0.515

High

283645

JTB
Protein JTB

1

0

High-throughput

0.513

High

380366

CD3D
T-cell surface glycoprotein CD3 delta chain

1

0

High-throughput

0.513

High

439792

NEP
Neprilysin

1

0

Small-scale

0.513

High

677130

ACHB4
Neuronal acetylcholine receptor subunit beta-4

1

0

High-throughput

0.513

High

819530

PCP4
Calmodulin regulator protein PCP4

1

0

High-throughput

0.513

High

871912

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

0

High-throughput

0.513

High

871916

RTP2
Receptor-transporting protein 2

1

0

High-throughput

0.513

High

871923

SO4C1
Solute carrier organic anion transporter family member 4C1

1

0

High-throughput

0.513

High

871932

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.513

High

871956

5NT1A
Cytosolic 5'-nucleotidase 1A

1

0

High-throughput

0.513

High

871958

CEP41
Centrosomal protein of 41 kDa

1

0

High-throughput

0.513

High

871979

PILRB
Paired immunoglobulin-like type 2 receptor beta

1

0

High-throughput

0.513

High

871984

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.513

High

49450

CLRN2
Clarin-2

1

1

High-throughput

0.489

High

130473

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

1

High-throughput

0.489

High

217083

NKG2F
NKG2-F type II integral membrane protein

1

3

High-throughput

0.489

High

238854

TPST2
Protein-tyrosine sulfotransferase 2

1

2

High-throughput

0.489

High

279239

LYZL6
Lysozyme-like protein 6

1

2

High-throughput

0.489

High

305399

ZFPL1
Zinc finger protein-like 1

1

2

High-throughput

0.489

High

518297

ADT3
ADP/ATP translocase 3

1

4

High-throughput

0.489

High

595525

GRAH
Granzyme H

1

4

High-throughput

0.489

High

606993

UD14
UDP-glucuronosyltransferase 1A4

1

1

High-throughput

0.489

High

871897

SIA4A
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1

1

4

High-throughput

0.489

High

871903

LAGE3
EKC/KEOPS complex subunit LAGE3

1

2

High-throughput

0.489

High

871918

FAXC
Failed axon connections homolog

1

1

High-throughput

0.489

High

871937

LRN4L
LRRN4 C-terminal-like protein

1

1

High-throughput

0.489

High

871939

B3GN7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7

1

5

High-throughput

0.489

High

871943

HUMMR
Protein MGARP

1

1

High-throughput

0.489

High

871952

SEC62
Translocation protein SEC62

1

4

High-throughput

0.489

High

871955

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

12

High-throughput

0.489

High

871964

G3ST2
Galactose-3-O-sulfotransferase 2

1

1

High-throughput

0.489

High

871978

DKKL1
Dickkopf-like protein 1

1

1

High-throughput

0.489

High

871982

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

4

High-throughput

0.489

High

871989

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

2

High-throughput

0.489

High

149977

CTDS2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

1

3

High-throughput

0.479

High

384557

NTRK1
High affinity nerve growth factor receptor

1

6

High-throughput

0.479

High

127000

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.458

High

871940

O10G2
Olfactory receptor 10G2

1

0

High-throughput

0.458

High

354935

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

11

High-throughput

0.445

High

379165

MYCN
N-myc proto-oncogene protein

1

3

High-throughput

0.437

High

871929

PLD3
5'-3' exonuclease PLD3

1

1

High-throughput

0.437

High

871981

TRI33
E3 ubiquitin-protein ligase TRIM33

1

4

High-throughput

0.437

High

92667

E9PNY5
Low affinity immunoglobulin gamma Fc region receptor III-A

1

1

High-throughput

0.407

High

871915

Q5J1K9
Mono-ADP-ribosyltransferase 3 variant Ia

1

1

High-throughput

0.407

High

871965

TRABD
TraB domain-containing protein

3

0

High-throughput

0.347

High

871902

I13R2
Interleukin-13 receptor subunit alpha-2

2

0

High-throughput

0.328

High

871911

ODFP4
Outer dense fiber protein 4

2

0

High-throughput

0.328

High

871921

IIGP5
Interferon-inducible GTPase 5

2

0

High-throughput

0.328

High

362520

C1QB
Complement C1q subcomponent subunit B

2

0

High-throughput

0.318

High

351871

NPY
Pro-neuropeptide Y [Cleaved into: Neuropeptide Y

1

0

High-throughput

0.282

High

158642

TIM23
Mitochondrial import inner membrane translocase subunit Tim23

1

0

High-throughput

0.279

Low

213718

ENSA
Alpha-endosulfine

1

0

High-throughput

0.279

Low

871892

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.279

Low

871914

KCP3
Keratinocyte-associated protein 3

1

0

High-throughput

0.279

Low

871920

NIPA3
Magnesium transporter NIPA3

1

0

High-throughput

0.279

Low

871922

BRID5
BRICHOS domain-containing protein 5

1

0

High-throughput

0.279

Low

871933

KTAP2
Keratinocyte-associated protein 2

1

0

High-throughput

0.279

Low

871938

WFD11
Protein WFDC11

1

0

High-throughput

0.279

Low

871946

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

871947

NUD16
U8 snoRNA-decapping enzyme

1

0

High-throughput

0.279

Low

871950

MR1L1
MORF4 family-associated protein 1-like 1

1

0

High-throughput

0.279

Low

871951

LCFC1
Sperm-egg fusion protein LLCFC1

1

0

High-throughput

0.279

Low

871966

EMRE
Essential MCU regulator, mitochondrial

1

0

High-throughput

0.279

Low

871976

NAT8B
Putative N-acetyltransferase 8B

1

0

High-throughput

0.279

Low

871988

HS3S4
Heparan sulfate glucosamine 3-O-sulfotransferase 4

1

0

High-throughput

0.279

Low

871990

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024