HitPredict

Interactor 1: BAG4 (O95429)
BAG family molecular chaperone regulator 4 (BAG-4) (Bcl-2-associated athanogene 4) (Silencer of death domains)
Gene: BAG4

Interactor 2: DNJB1 (P25685)
DnaJ homolog subfamily B member 1 (DnaJ protein homolog 1) (Heat shock 40 kDa protein 1) (HSP40) (Heat shock protein 40) (Human DnaJ protein 1) (hDj-1)
Gene: DNAJB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25036637
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0051087 - protein-folding chaperone binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 457 Hs			1 340
+	Hs
		279266 BAG4_HUMAN (1-457): 0: 698: 100.00		DNJB5_HUMAN (1-339): 3.31e-126: 366: 59.71
+	Hs
		324663 BAG3_HUMAN (354-457): 1.21e-22: 102: 47.12		DNJB4_HUMAN (1-339): 1.15e-134: 388: 64.60
+	Hs
		636441 BAG5_HUMAN (370-456): 3.04e-16: 82.5: 41.38		DNJB1_HUMAN (1-340): 5.05e-137: 394: 100.00
+	Hs
		1354514 BAG5_HUMAN (370-456): 3.04e-16: 82.5: 41.38		DNJB4_HUMAN (1-339): 1.15e-134: 388: 64.60
+	Hs
		279359 BAG5_HUMAN (370-456): 3.04e-16: 82.5: 41.38		DNJB5_HUMAN (1-339): 3.31e-126: 366: 59.71
+	Hs
		243236 BAG3_HUMAN (354-457): 1.21e-22: 102: 47.12		DNJA2_HUMAN (2-339): 2.35e-115: 341: 33.24
+	Hs
		681645 BAG5_HUMAN (370-456): 3.04e-16: 82.5: 41.38		DNJA1_HUMAN (5-339): 2.97e-117: 346: 32.77
+	Hs
		1262169 BAG5_HUMAN (370-456): 3.04e-16: 82.5: 41.38		DNJA4_HUMAN (5-339): 1.42e-115: 341: 32.49
+	Hs
		243665 BAG5_HUMAN (370-456): 3.04e-16: 82.5: 41.38		DNJA2_HUMAN (2-339): 2.35e-115: 341: 33.24
+	Hs
		1354287 BAG5_HUMAN (370-456): 3.04e-16: 82.5: 41.38		DJB11_HUMAN (2-338): 8.5e-105: 313: 32.26