Interactor 1: ABCA1 (O95477)
Phospholipid-transporting ATPase ABCA1 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 1) (ATP-binding cassette transporter 1) (ABC-1) (ATP-binding cassette 1) (Cholesterol efflux regulatory protein)
Gene: ABCA1
Interactor 2: ABCAC (Q86UK0)
Glucosylceramide transporter ABCA12 (EC 7.6.2.1) (ATP-binding cassette sub-family A member 12) (ATP-binding cassette transporter 12) (ATP-binding cassette 12)
Gene: ABCA12
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.665 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23931754 |
| Identification Methods | anti bait coimmunoprecipitation, anti tag coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ABC2_membrane_3~ABC2_membrane_3, ABC2_membrane_3~ABC_tran, ABC_tran~ABC_tran |
| Common GO terms | GO:0005102 - signaling receptor binding GO:0005524 - ATP binding GO:0005886 - plasma membrane GO:0010875 - positive regulation of cholesterol efflux GO:0016887 - ATP hydrolysis activity and 5 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
