HitPredict

Interactor 1: CBX6 (O95503)
Chromobox protein homolog 6
Gene: CBX6

Interactor 2: H12 (P16403)
Histone H1.2 (Histone H1c) (Histone H1d) (Histone H1s-1)
Gene: H1-2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	24981860, 21282530
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 412 Hs			1 213
+	Hs
		315955 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		H14_HUMAN (1-172): 4.96e-18: 80.6: 88.37
+	Hs
		315961 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		H15_HUMAN (1-157): 2.05e-15: 74.1: 76.25
+	Hs
		316015 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		H11_HUMAN (38-182): 2.87e-15: 73.3: 62.07
+	Hs
		489290 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		H14_HUMAN (1-172): 4.96e-18: 80.6: 88.37
+	Hs
		559255 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		H15_HUMAN (1-157): 2.05e-15: 74.1: 76.25
+	Hs
		123239 CBX4_HUMAN (1-362): 3.71e-34: 135: 23.28		H11_HUMAN (38-182): 2.87e-15: 73.3: 62.07
+	Mm
		794626 CBX5_MOUSE (11-106): 1.59e-27: 109: 29.17		H14_MOUSE (1-201): 1.2e-22: 93: 66.83
+	Mm
		794637 Q9DCC5_MOUSE (9-121): 1.26e-25: 104: 24.56		H14_MOUSE (1-201): 1.2e-22: 93: 66.83
+	Hs
		488936 CBX5_HUMAN (11-106): 3.1e-28: 111: 29.17		H14_HUMAN (1-172): 4.96e-18: 80.6: 88.37
+	Mm
		794619 CBX1_MOUSE (17-85): 6.16e-23: 97.1: 34.78		H14_MOUSE (1-201): 1.2e-22: 93: 66.83
+	Hs
		559009 CBX5_HUMAN (11-106): 3.1e-28: 111: 29.17		H15_HUMAN (1-157): 2.05e-15: 74.1: 76.25
+	Hs
		489023 CBX3_HUMAN (9-121): 1.26e-25: 104: 24.56		H14_HUMAN (1-172): 4.96e-18: 80.6: 88.37
+	Mm
		794648 CBX5_MOUSE (11-106): 1.59e-27: 109: 29.17		H11_MOUSE (1-121): 1.59e-14: 71.4: 69.11