HitPredict

Interactor 1: CBX6 (O95503)
Chromobox protein homolog 6
Gene: CBX6

Interactor 2: H2B1B (P33778)
Histone H2B type 1-B (H2B-clustered histone 3) (Histone H2B.1) (Histone H2B.f) (H2B/f)
Gene: H2BC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21282530
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 412 Hs			1 126
+	Hs
		316041 CBX6_HUMAN (1-393): 1.39e-116: 347: 100.00		H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41
+	Hs
		1087415 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41
+	Hs
		241642 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		H2B1K_HUMAN (1-126): 1.48e-54: 168: 96.83
+	Hs
		707753 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00
+	Hs
		918703 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		H2B1C_HUMAN (1-126): 1.27e-54: 168: 97.62
+	Hs
		1282967 CBX8_HUMAN (1-393): 2.31e-76: 243: 30.82		H2B1A_HUMAN (1-126): 8.03e-47: 148: 85.83
+	Hs
		1087361 MPP8_HUMAN (6-339): 4.19e-48: 177: 14.91		H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41
+	Hs
		918634 MPP8_HUMAN (6-339): 4.19e-48: 177: 14.91		H2B1C_HUMAN (1-126): 1.27e-54: 168: 97.62
+	Dm
		355256 PC_DROME (10-393): 7.49e-58: 196: 21.04		H2B_DROME (36-126): 1.48e-46: 148: 95.60
+	Hs
		1087494 CDYL_HUMAN (2-275): 6.83e-44: 163: 17.08		H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41
+	Hs
		918778 CDYL_HUMAN (2-275): 6.83e-44: 163: 17.08		H2B1C_HUMAN (1-126): 1.27e-54: 168: 97.62
+	Hs
		1231263 CDYL_HUMAN (2-275): 6.83e-44: 163: 17.08		H2B3B_HUMAN (1-126): 2.37e-52: 163: 96.03
+	Hs
		1282983 CDYL_HUMAN (2-275): 6.83e-44: 163: 17.08		H2B1A_HUMAN (1-126): 8.03e-47: 148: 85.83
+	Hs
		203602 SUV91_HUMAN (11-222): 8.35e-36: 137: 17.21		H2B1K_HUMAN (1-126): 1.48e-54: 168: 96.83
+	Hs
		123255 CBX4_HUMAN (1-362): 3.71e-34: 135: 23.28		H2B2E_HUMAN (1-126): 7.04e-55: 169: 98.41
+	Hs
		123191 CBX4_HUMAN (1-362): 3.71e-34: 135: 23.28		H2B1B_HUMAN (1-126): 1.3e-54: 168: 100.00
+	Hs
		123222 CBX4_HUMAN (1-362): 3.71e-34: 135: 23.28		H2B1C_HUMAN (1-126): 1.27e-54: 168: 97.62
+	Sp
		223810 CLR4_SCHPO (8-294): 7.67e-43: 158: 17.45		H2B1_SCHPO (4-125): 1.37e-45: 145: 69.67
+	Hs
		241469 CBX5_HUMAN (11-106): 3.1e-28: 111: 29.17		H2B1K_HUMAN (1-126): 1.48e-54: 168: 96.83
+	Hs
		800336 CBX5_HUMAN (11-106): 3.1e-28: 111: 29.17		H2B1C_HUMAN (1-126): 1.27e-54: 168: 97.62