Protein: SMAD9
Mothers against decapentaplegic homolog 9 (MAD homolog 9) (Mothers against DPP homolog 9) (Madh6) (SMAD family member 9) (SMAD 9) (Smad9)

Gene: SMAD9
Organism: Homo sapiens
Interactions: 133
UniProt ID: O15198

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

171394

SMAD4
Mothers against decapentaplegic homolog 4

8

19

Small-scale

0.966

High

171384

SMAD3
Mothers against decapentaplegic homolog 3

3

19

High-throughput

0.861

High

171399

SMAD2
Mothers against decapentaplegic homolog 2

2

19

High-throughput

0.806

High

171465

MAN1
Inner nuclear membrane protein Man1

7

14

Small-scale

0.682

High

171386

PSG9
Pregnancy-specific beta-1-glycoprotein 9

3

3

High-throughput

0.667

High

171412

DSG4
Desmoglein-4

3

4

High-throughput

0.667

High

167308

SMAD7
Mothers against decapentaplegic homolog 7

1

18

Small-scale

0.618

High

171343

SMAD9
Mothers against decapentaplegic homolog 9

1

19

Small-scale

0.618

High

171347

KDM1A
Lysine-specific histone demethylase 1A

1

5

High-throughput

0.573

High

171432

ANM6
Protein arginine N-methyltransferase 6

1

5

High-throughput

0.573

High

171369

NOTC1
Neurogenic locus notch homolog protein 1

1

11

High-throughput

0.536

High

171441

BCL7B
B-cell CLL/lymphoma 7 protein family member B

1

2

High-throughput

0.536

High

171464

2ABG
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform

1

1

High-throughput

0.536

High

48081

UBA6
Ubiquitin-like modifier-activating enzyme 6

1

2

High-throughput

0.508

High

59902

MTMRB
Myotubularin-related protein 11

1

4

High-throughput

0.508

High

152555

KMT2D
Histone-lysine N-methyltransferase 2D

1

14

High-throughput

0.508

High

171344

KDM6A
Lysine-specific demethylase 6A

1

9

High-throughput

0.508

High

171345

ZEB2
Zinc finger E-box-binding homeobox 2

1

15

High-throughput

0.508

High

171346

GANP
Germinal-center associated nuclear protein

1

5

High-throughput

0.508

High

171351

SF3B1
Splicing factor 3B subunit 1

1

5

High-throughput

0.508

High

171353

AP2A1
AP-2 complex subunit alpha-1

1

2

High-throughput

0.508

High

171359

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

8

High-throughput

0.508

High

171362

RFX1
MHC class II regulatory factor RFX1

1

7

High-throughput

0.508

High

171365

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

6

High-throughput

0.508

High

171370

SYQ
Glutamine--tRNA ligase

1

1

High-throughput

0.508

High

171371

PSMD8
26S proteasome non-ATPase regulatory subunit 8

1

1

High-throughput

0.508

High

171373

ZNF83
Zinc finger protein 83

1

3

High-throughput

0.508

High

171377

MAP11
Methionine aminopeptidase 1

1

1

High-throughput

0.508

High

171378

TERF1
Telomeric repeat-binding factor 1

1

1

High-throughput

0.508

High

171381

ACTB
Actin, cytoplasmic 1

1

1

High-throughput

0.508

High

171382

DEST
Destrin

1

1

High-throughput

0.508

High

171383

LMO4
LIM domain transcription factor LMO4

1

7

High-throughput

0.508

High

171387

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

5

High-throughput

0.508

High

171388

FLI1
Friend leukemia integration 1 transcription factor

1

4

High-throughput

0.508

High

171390

DYST
Dystonin

1

5

High-throughput

0.508

High

171391

PPARD
Peroxisome proliferator-activated receptor delta

1

13

High-throughput

0.508

High

171393

PABP4
Polyadenylate-binding protein 4

1

1

High-throughput

0.508

High

171396

TRIPC
E3 ubiquitin-protein ligase TRIP12

1

20

High-throughput

0.508

High

171398

PLEC
Plectin

1

5

High-throughput

0.508

High

171403

SVEP1
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1

1

9

High-throughput

0.508

High

171404

CAMP1
Calmodulin-regulated spectrin-associated protein 1

1

1

High-throughput

0.508

High

171405

RN123
E3 ubiquitin-protein ligase RNF123

1

9

High-throughput

0.508

High

171407

E4F1
Transcription factor E4F1

1

2

High-throughput

0.508

High

171408

CTR9
RNA polymerase-associated protein CTR9 homolog

1

3

High-throughput

0.508

High

171409

SKI3
Superkiller complex protein 3

1

4

High-throughput

0.508

High

171411

CXXC5
CXXC-type zinc finger protein 5

1

3

High-throughput

0.508

High

171415

PELP1
Proline-, glutamic acid- and leucine-rich protein 1

1

13

High-throughput

0.508

High

171417

MACOI
Macoilin

1

1

High-throughput

0.508

High

171418

ZN557
Zinc finger protein 557

1

1

High-throughput

0.508

High

171419

ZSCA4
Zinc finger and SCAN domain-containing protein 4

1

4

High-throughput

0.508

High

171421

ARI1B
AT-rich interactive domain-containing protein 1B

1

16

High-throughput

0.508

High

171423

ZN592
Zinc finger protein 592

1

2

High-throughput

0.508

High

171427

ABTB1
Ankyrin repeat and BTB/POZ domain-containing protein 1

1

2

High-throughput

0.508

High

171428

PLPL2
Patatin-like phospholipase domain-containing protein 2

1

1

High-throughput

0.508

High

171429

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

2

High-throughput

0.508

High

171430

OTUB1
Ubiquitin thioesterase OTUB1

1

5

High-throughput

0.508

High

171434

ASB2
Ankyrin repeat and SOCS box protein 2

1

4

High-throughput

0.508

High

171436

RANB9
Ran-binding protein 9

1

9

High-throughput

0.508

High

171439

DNJC7
DnaJ homolog subfamily C member 7

1

8

High-throughput

0.508

High

171440

PKP2
Plakophilin-2

1

7

High-throughput

0.508

High

171442

RHG09
Rho GTPase-activating protein 9

1

3

High-throughput

0.508

High

171448

UN45A
Protein unc-45 homolog A

1

6

High-throughput

0.508

High

171450

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

4

High-throughput

0.508

High

171452

HEYL
Hairy/enhancer-of-split related with YRPW motif-like protein

1

6

High-throughput

0.508

High

171454

BAZ1A
Bromodomain adjacent to zinc finger domain protein 1A

1

20

High-throughput

0.508

High

171455

UBQL4
Ubiquilin-4

1

6

High-throughput

0.508

High

171458

MTMRA
Myotubularin-related protein 10

1

4

High-throughput

0.508

High

171460

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

8

High-throughput

0.508

High

171462

NAGK
N-acetyl-D-glucosamine kinase

1

1

High-throughput

0.508

High

171463

UBQL1
Ubiquilin-1

1

6

High-throughput

0.508

High

171466

HEY1
Hairy/enhancer-of-split related with YRPW motif protein 1

1

4

High-throughput

0.508

High

171461

CBPA4
Carboxypeptidase A4

1

1

High-throughput

0.489

High

124671

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

0

High-throughput

0.486

High

134696

PIR
Pirin

1

0

High-throughput

0.486

High

171349

LRP5
Low-density lipoprotein receptor-related protein 5

1

0

High-throughput

0.486

High

171355

FRIL
Ferritin light chain

1

0

High-throughput

0.486

High

171364

1433T
14-3-3 protein theta

1

0

High-throughput

0.486

High

171368

KPB2
Phosphorylase b kinase regulatory subunit alpha, liver isoform

1

0

High-throughput

0.486

High

171380

EIF3E
Eukaryotic translation initiation factor 3 subunit E

1

0

High-throughput

0.486

High

171402

2A5E
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

1

0

High-throughput

0.486

High

171406

CP135
Centrosomal protein of 135 kDa

1

0

High-throughput

0.486

High

171413

LBN
Limbin

1

0

High-throughput

0.486

High

171414

CHSS2
Chondroitin sulfate synthase 2

1

0

High-throughput

0.486

High

171416

VPS8
Vacuolar protein sorting-associated protein 8 homolog

1

0

High-throughput

0.486

High

171431

VCIP1
Deubiquitinating protein VCPIP1

1

0

High-throughput

0.486

High

171437

SEBP2
Selenocysteine insertion sequence-binding protein 2

1

0

High-throughput

0.486

High

171438

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

0

High-throughput

0.486

High

171443

TBCD
Tubulin-specific chaperone D

1

0

High-throughput

0.486

High

171446

CLPB
Mitochondrial disaggregase

1

0

High-throughput

0.486

High

171456

DIAP3
Protein diaphanous homolog 3

1

0

High-throughput

0.486

High

91504

Z587B
Zinc finger protein 587B

1

4

High-throughput

0.481

High

171360

CSH2
Chorionic somatomammotropin hormone 2

1

4

High-throughput

0.481

High

171350

MED24
Mediator of RNA polymerase II transcription subunit 24

1

5

Small-scale

0.479

High

171354

MYC
Myc proto-oncogene protein

1

11

High-throughput

0.479

High

171356

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

171367

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

1

4

High-throughput

0.479

High

171372

TOB1
Protein Tob1

1

11

Small-scale

0.479

High

171375

ZN143
Zinc finger protein 143

1

4

High-throughput

0.479

High

171376

HMGA2
High mobility group protein HMGI-C

1

3

Small-scale

0.479

High

171379

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

6

High-throughput

0.479

High

171385

VIGLN
Vigilin

1

2

High-throughput

0.479

High

171389

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.479

High

171400

EZH2
Histone-lysine N-methyltransferase EZH2

1

11

Small-scale

0.479

High

171410

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

171422

SMAP2
Stromal membrane-associated protein 2

1

1

High-throughput

0.479

High

171424

KAT2A
Histone acetyltransferase KAT2A

1

20

Small-scale

0.479

High

171425

KAT2B
Histone acetyltransferase KAT2B

1

13

Small-scale

0.479

High

171451

MED4
Mediator of RNA polymerase II transcription subunit 4

1

3

Small-scale

0.479

High

171457

MED29
Mediator of RNA polymerase II transcription subunit 29

1

1

Small-scale

0.479

High

171348

MA1A2
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

1

1

High-throughput

0.464

High

171357

CP11A
Cholesterol side-chain cleavage enzyme, mitochondrial

1

3

High-throughput

0.464

High

171358

SAP
Prosaposin

1

1

High-throughput

0.464

High

171374

AFF1
AF4/FMR2 family member 1

1

6

High-throughput

0.464

High

171392

PAPP1
Pappalysin-1

1

10

High-throughput

0.464

High

171395

TRI29
Tripartite motif-containing protein 29

1

1

High-throughput

0.464

High

171453

MA1C1
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC

1

1

High-throughput

0.464

High

171459

RRBP1
Ribosome-binding protein 1

1

9

High-throughput

0.464

High

171444

DPY30
Protein dpy-30 homolog

1

0

Small-scale

0.458

High

171426

Q92967
Zinc finger protein zfp6

1

2

High-throughput

0.457

High

78633

ERVV1
Endogenous retrovirus group V member 1 Env polyprotein

1

1

High-throughput

0.439

High

171397

Q149M6
Exophilin 5

1

1

High-throughput

0.439

High

171435

PEO1
Twinkle mtDNA helicase

1

1

High-throughput

0.439

High

171401

CRY1
Cryptochrome-1

1

0

Small-scale

0.426

High

171420

EXPH5
Exophilin-5

1

1

High-throughput

0.417

High

171433

Q96MK7
cDNA FLJ32214 fis, clone PLACE6003705

1

1

High-throughput

0.417

High

171449

Q9H6V3
C10orf2 protein

1

1

High-throughput

0.417

High

171366

GRN
Progranulin

2

0

High-throughput

0.323

High

171361

VSIG8
V-set and immunoglobulin domain-containing protein 8

2

0

High-throughput

0.288

High

171352

DKK1
Dickkopf-related protein 1

1

0

High-throughput

0.265

Low

171363

MGAT1
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

1

0

High-throughput

0.265

Low

171445

TINAL
Tubulointerstitial nephritis antigen-like

1

0

High-throughput

0.265

Low

171447

SIL1
Nucleotide exchange factor SIL1

1

0

High-throughput

0.265

Low


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Last updated: 15 Jul 2024