HitPredict

Interactor 1: ACSL3 (O95573)
Fatty acid CoA ligase Acsl3 (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 3) (LACS 3) (Long-chain-fatty-acid--CoA ligase 3) (EC 6.2.1.3) (Medium-chain acyl-CoA ligase Acsl3) (EC 6.2.1.2)
Gene: ACSL3

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32877691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005741 - mitochondrial outer membrane GO:0016020 - membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 720 Hs			1 618
+	Hs
		316568 ACSL3_HUMAN (1-720): 0: 743: 100.00		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		316610 ACSL3_HUMAN (1-720): 0: 743: 100.00		RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22
+	Hs
		316611 ACSL3_HUMAN (1-720): 0: 743: 100.00		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		316646 ACSL3_HUMAN (1-720): 0: 743: 100.00		RAB35_HUMAN (5-168): 3.51e-76: 242: 24.70
+	Hs
		316626 ACSL3_HUMAN (1-720): 0: 743: 100.00		RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47
+	Hs
		316622 ACSL3_HUMAN (1-720): 0: 743: 100.00		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		234801 ACSL4_HUMAN (12-720): 0: 706: 65.54		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		316619 ACSL3_HUMAN (1-720): 0: 743: 100.00		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		316614 ACSL3_HUMAN (1-720): 0: 743: 100.00		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		316733 ACSL3_HUMAN (1-720): 0: 743: 100.00		RHOF_HUMAN (2-167): 3.37e-11: 65.1: 26.67
+	Hs
		316555 ACSL3_HUMAN (1-720): 0: 743: 100.00		RHOC_HUMAN (6-168): 3.86e-11: 64.3: 28.25
+	Hs
		120262 ACSL3_HUMAN (1-720): 0: 743: 100.00		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Hs
		234807 ACSL4_HUMAN (12-720): 0: 706: 65.54		RHOB_HUMAN (6-168): 4.57e-13: 70.1: 29.38
+	Hs
		234803 ACSL4_HUMAN (12-720): 0: 706: 65.54		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25