Protein: ARSK
Arylsulfatase K (ASK) (EC 3.1.6.1) (Glucuronate-2-sulfatase) (EC 3.1.6.18) (Telethon sulfatase)

Gene: ARSK
Organism: Homo sapiens
Interactions: 88
UniProt ID: Q6UWY0

Gene Ontology (top 5):
GO:0004065 - arylsulfatase activity
GO:0005576 - extracellular region
GO:0005764 - lysosome
GO:0005788 - endoplasmic reticulum lumen
GO:0015024 - glucuronate-2-sulfatase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

154833

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

3

3

High-throughput

0.667

High

1034760

NAAA
N-acylethanolamine-hydrolyzing acid amidase

3

6

High-throughput

0.667

High

1042636

UPAR
Urokinase plasminogen activator surface receptor

3

4

High-throughput

0.667

High

1143724

PON2
Serum paraoxonase/arylesterase 2

3

1

High-throughput

0.667

High

1219207

SUSD4
Sushi domain-containing protein 4

3

2

High-throughput

0.667

High

1248910

TMM25
Transmembrane protein 25

3

2

High-throughput

0.667

High

698787

CALX
Calnexin

2

9

High-throughput

0.628

High

1248760

LYZL1
Lysozyme-like protein 1

2

5

High-throughput

0.628

High

1248938

INSL5
Insulin-like peptide INSL5

2

4

High-throughput

0.628

High

1248928

SIAE
Sialate O-acetylesterase

2

3

High-throughput

0.611

High

1116226

PTC1
Protein patched homolog 1

3

1

High-throughput

0.609

High

1144615

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

3

4

High-throughput

0.609

High

1160397

TAZ
Tafazzin

3

2

High-throughput

0.609

High

1248924

LACRT
Extracellular glycoprotein lacritin

2

0

High-throughput

0.602

High

1248925

LMA2L
VIP36-like protein

2

0

High-throughput

0.602

High

1108507

NAR3
Ecto-ADP-ribosyltransferase 3

2

3

High-throughput

0.584

High

351701

SG1D1
Secretoglobin family 1D member 1

2

2

High-throughput

0.574

High

1101362

SG2A2
Mammaglobin-A

2

6

High-throughput

0.574

High

1248907

SG1D4
Secretoglobin family 1D member 4

2

2

High-throughput

0.574

High

1248930

FBX6
F-box only protein 6

2

10

High-throughput

0.558

High

316668

LY6H
Lymphocyte antigen 6H

1

1

High-throughput

0.536

High

342595

LY86
Lymphocyte antigen 86

1

2

High-throughput

0.536

High

351785

LGI1
Leucine-rich glioma-inactivated protein 1

1

4

High-throughput

0.536

High

388720

C1QB
Complement C1q subcomponent subunit B

1

4

High-throughput

0.536

High

416626

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

2

High-throughput

0.536

High

458014

TRY2
Trypsin-2

1

5

High-throughput

0.536

High

535208

BIP
Endoplasmic reticulum chaperone BiP

1

7

High-throughput

0.536

High

567895

PRG2
Bone marrow proteoglycan

1

6

High-throughput

0.536

High

570683

EDN3
Endothelin-3

1

1

High-throughput

0.536

High

628419

KLK2
Kallikrein-2

1

11

High-throughput

0.536

High

682526

S100P
Protein S100-P

1

4

High-throughput

0.536

High

702401

CYTD
Cystatin-D

1

4

High-throughput

0.536

High

935752

MFAP4
Microfibril-associated glycoprotein 4

1

5

High-throughput

0.536

High

942377

EP3B
Epididymal secretory protein E3-beta

1

2

High-throughput

0.536

High

948000

DEF1
Neutrophil defensin 1

1

4

High-throughput

0.536

High

976821

LCN6
Epididymal-specific lipocalin-6

1

3

High-throughput

0.536

High

1083501

BST1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2

1

1

High-throughput

0.536

High

1236102

FSTL4
Follistatin-related protein 4

1

2

High-throughput

0.536

High

1248911

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

3

High-throughput

0.536

High

1248912

SUMF2
Inactive C-alpha-formylglycine-generating enzyme 2

1

13

High-throughput

0.536

High

1248913

SUMF1
Formylglycine-generating enzyme

1

13

High-throughput

0.536

High

1248917

CA054
Uncharacterized protein C1orf54

1

6

High-throughput

0.536

High

1248918

GGH
Gamma-glutamyl hydrolase

1

3

High-throughput

0.536

High

1248920

ESPB1
Epididymal sperm-binding protein 1

1

7

High-throughput

0.536

High

1248922

LCFC1
Sperm-egg fusion protein LLCFC1

1

4

High-throughput

0.536

High

1248926

DPEP2
Dipeptidase 2

1

2

High-throughput

0.536

High

1248929

SDF2L
Stromal cell-derived factor 2-like protein 1

1

2

High-throughput

0.536

High

1248931

FKB14
Peptidyl-prolyl cis-trans isomerase FKBP14

1

3

High-throughput

0.536

High

1248932

DNJB9
DnaJ homolog subfamily B member 9

1

1

High-throughput

0.536

High

1248936

PRG3
Proteoglycan 3

1

5

High-throughput

0.536

High

1248939

LIPG
Endothelial lipase

1

2

High-throughput

0.536

High

485940

GIP
Gastric inhibitory polypeptide

1

0

High-throughput

0.513

High

1248915

FIBIN
Fin bud initiation factor homolog

1

0

High-throughput

0.513

High

1248916

NEUFC
Neuferricin

1

0

High-throughput

0.513

High

62197

PRS37
Probable inactive serine protease 37

1

10

High-throughput

0.489

High

168421

NCTR3
Natural cytotoxicity triggering receptor 3

1

2

High-throughput

0.489

High

170823

CLGN
Calmegin

1

9

High-throughput

0.489

High

224493

PI15
Peptidase inhibitor 15

1

3

High-throughput

0.489

High

286556

SG2A1
Mammaglobin-B

1

6

High-throughput

0.489

High

426106

PPB1
Alkaline phosphatase, placental type

1

2

High-throughput

0.489

High

593404

PGFRA
Platelet-derived growth factor receptor alpha

1

6

High-throughput

0.489

High

731864

CEAM8
Cell adhesion molecule CEACAM8

1

4

High-throughput

0.489

High

1030180

IL5RA
Interleukin-5 receptor subunit alpha

1

4

High-throughput

0.489

High

1101274

SLAF1
Signaling lymphocytic activation molecule

1

5

High-throughput

0.489

High

1131187

MESD
LRP chaperone MESD

1

5

High-throughput

0.489

High

1177812

CL12B
C-type lectin domain family 12 member B

1

2

High-throughput

0.489

High

1245863

BRID5
BRICHOS domain-containing protein 5

1

1

High-throughput

0.489

High

1248923

C1QT7
Complement C1q tumor necrosis factor-related protein 7

1

4

High-throughput

0.489

High

1248927

CST9L
Cystatin-9-like

1

4

High-throughput

0.489

High

1248934

FBX2
F-box only protein 2

1

10

High-throughput

0.489

High

1248940

SPCS1
Signal peptidase complex subunit 1

1

1

High-throughput

0.489

High

218347

TGON2
Trans-Golgi network integral membrane protein 2

1

6

High-throughput

0.479

High

1248935

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

0

High-throughput

0.458

High

222293

PSCA
Prostate stem cell antigen

1

3

High-throughput

0.445

High

321274

ERLN2
Erlin-2

1

1

High-throughput

0.437

High

869049

TISD
mRNA decay activator protein ZFP36L2

1

1

High-throughput

0.437

High

399452

TRGV3
T cell receptor gamma variable 3

1

1

High-throughput

0.407

High

1181076

DB109
Beta-defensin 109B

1

2

High-throughput

0.407

High

1205409

Q5J1K9
Mono-ADP-ribosyltransferase 3 variant Ia

1

1

High-throughput

0.407

High

1136125

SPCS2
Signal peptidase complex subunit 2

1

0

High-throughput

0.279

Low

1248908

ZN621
Zinc finger protein 621

1

0

High-throughput

0.279

Low

1248909

BTLA
B- and T-lymphocyte attenuator

1

0

High-throughput

0.279

Low

1248914

TM87A
Transmembrane protein 87A

1

0

High-throughput

0.279

Low

1248919

T106A
Transmembrane protein 106A

1

0

High-throughput

0.279

Low

1248921

ATG2B
Autophagy-related protein 2 homolog B

1

0

High-throughput

0.279

Low

1248933

BTNL2
Butyrophilin-like protein 2

1

0

High-throughput

0.279

Low

1248937

WIPI4
WD repeat domain phosphoinositide-interacting protein 4

1

0

High-throughput

0.279

Low

774438

BASI
Basigin

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025