HitPredict

Interactor 1: KLF8 (O95600)
Krueppel-like factor 8 (Basic krueppel-like factor 3) (Zinc finger protein 741)
Gene: KLF8

Interactor 2: PRC2C (Q9Y520)
Protein PRRC2C (BAT2 domain-containing protein 1) (HBV X-transactivated gene 2 protein) (HBV XAg-transactivated protein 2) (HLA-B-associated transcript 2-like 2) (Proline-rich and coiled-coil-containing protein 2C)
Gene: PRRC2C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35140242
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 359 Hs			1 2896
+	Hs
		316970 KLF8_HUMAN (1-356): 5.7e-92: 281: 100.00		MINT_HUMAN (22-1891): 2.31e-43: 178: 9.12
+	Hs
		317047 KLF8_HUMAN (1-356): 5.7e-92: 281: 100.00		NCOR2_HUMAN (685-2896): 1.59e-24: 115: 7.48
+	Hs
		316821 KLF8_HUMAN (1-356): 5.7e-92: 281: 100.00		PRC2A_HUMAN (1183-2870): 8.38e-21: 103: 8.16
+	Hs
		316907 KLF8_HUMAN (1-356): 5.7e-92: 281: 100.00		PRC2B_HUMAN (894-2896): 3.68e-13: 78.3: 6.73
+	Hs
		316969 KLF8_HUMAN (1-356): 5.7e-92: 281: 100.00		CIC_HUMAN (57-1435): 3.5e-10: 68.5: 9.73
+	Hs
		435196 SP1_HUMAN (90-358): 1.01e-66: 226: 30.48		NCOR2_HUMAN (685-2896): 1.59e-24: 115: 7.48
+	Hs
		1301020 KLF12_HUMAN (44-356): 6.24e-85: 264: 42.58		CIC_HUMAN (57-1435): 3.5e-10: 68.5: 9.73
+	Hs
		435145 SP1_HUMAN (90-358): 1.01e-66: 226: 30.48		TITIN_HUMAN (1221-2896): 4.19e-20: 101: 7.44
+	Hs
		1078419 ZKSC8_HUMAN (7-277): 1.54e-69: 229: 10.07		CIC_HUMAN (57-1435): 3.5e-10: 68.5: 9.73
+	Hs
		884274 KLF3_HUMAN (22-356): 2.98e-51: 175: 34.19		NCOR2_HUMAN (685-2896): 1.59e-24: 115: 7.48
+	Hs
		1046778 KLF5_HUMAN (267-356): 1.18e-41: 152: 78.89		NCOR2_HUMAN (685-2896): 1.59e-24: 115: 7.48
+	Hs
		820916 KLF5_HUMAN (267-356): 1.18e-41: 152: 78.89		PRC2A_HUMAN (1183-2870): 8.38e-21: 103: 8.16
+	Hs
		204195 KLF4_HUMAN (105-356): 4.72e-49: 174: 32.56		KMT2C_HUMAN (1901-2885): 8.54e-14: 80.6: 9.27
+	Hs
		1132368 ZN362_HUMAN (49-356): 1.26e-52: 181: 24.50		CIC_HUMAN (57-1435): 3.5e-10: 68.5: 9.73
+	Hs
		884227 KLF3_HUMAN (22-356): 2.98e-51: 175: 34.19		CIC_HUMAN (57-1435): 3.5e-10: 68.5: 9.73
+	Hs
		1046715 KLF5_HUMAN (267-356): 1.18e-41: 152: 78.89		KMT2C_HUMAN (1901-2885): 8.54e-14: 80.6: 9.27
+	Hs
		1046695 KLF5_HUMAN (267-356): 1.18e-41: 152: 78.89		PRC2B_HUMAN (894-2896): 3.68e-13: 78.3: 6.73
+	Hs
		1046684 KLF5_HUMAN (267-356): 1.18e-41: 152: 78.89		NCOA6_HUMAN (37-1027): 9.61e-13: 76.7: 7.69
+	Hs
		821074 KLF15_HUMAN (272-356): 1.38e-31: 125: 63.53		PRC2A_HUMAN (1183-2870): 8.38e-21: 103: 8.16
+	Hs
		1046742 KLF5_HUMAN (267-356): 1.18e-41: 152: 78.89		CIC_HUMAN (57-1435): 3.5e-10: 68.5: 9.73