Protein: MTA3
Metastasis-associated protein MTA3

Gene: MTA3
Organism: Homo sapiens
Interactions: 180
UniProt ID: Q9BTC8

Gene Ontology (top 5):
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003682 - chromatin binding
GO:0003713 - transcription coactivator activity
GO:0003714 - transcription corepressor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1110039

HDAC1
Histone deacetylase 1

13

20

Small-scale

0.980

High

1158982

RBBP7
Histone-binding protein RBBP7

10

16

Small-scale

0.973

High

1066468

RBBP4
Histone-binding protein RBBP4

7

16

High-throughput

0.967

High

1368092

HDAC2
Histone deacetylase 2

9

20

Small-scale

0.967

High

1132937

CHD4
Chromodomain-helicase-DNA-binding protein 4

7

20

Small-scale

0.958

High

1360999

P66B
Transcriptional repressor p66-beta

6

6

High-throughput

0.947

High

352235

MBD3
Methyl-CpG-binding domain protein 3

6

16

Small-scale

0.925

High

1295296

P66A
Transcriptional repressor p66-alpha

4

6

High-throughput

0.903

High

998752

H31
Histone H3.1

4

20

High-throughput

0.873

High

246909

KDM1A
Lysine-specific histone demethylase 1A

3

18

Small-scale

0.866

High

1088535

CHD3
Chromodomain-helicase-DNA-binding protein 3

3

20

Small-scale

0.847

High

1413363

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

3

20

Small-scale

0.827

High

1413366

TCF19
Transcription factor 19

2

2

High-throughput

0.811

High

316968

MTA2
Metastasis-associated protein MTA2

2

12

High-throughput

0.789

High

1413355

MBD2
Methyl-CpG-binding domain protein 2

2

16

High-throughput

0.789

High

1413360

TRPS1
Zinc finger transcription factor Trps1

2

20

High-throughput

0.776

High

210343

PHF1
PHD finger protein 1

2

9

Small-scale

0.754

High

1351284

CHD5
Chromodomain-helicase-DNA-binding protein 5

2

20

Small-scale

0.754

High

662644

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

20

Small-scale

0.748

High

1102642

MTA1
Metastasis-associated protein MTA1

2

12

High-throughput

0.737

High

155347

CDKA1
Cyclin-dependent kinase 2-associated protein 1

6

8

Small-scale

0.722

High

1413354

ZN219
Zinc finger protein 219

4

6

High-throughput

0.694

High

1359977

MB3L1
Methyl-CpG-binding domain protein 3-like 1

3

16

High-throughput

0.667

High

911359

IMA5
Importin subunit alpha-5

3

14

High-throughput

0.650

High

1104660

IKZF1
DNA-binding protein Ikaros

2

6

High-throughput

0.628

High

1180353

ZN800
Zinc finger protein 800

2

2

High-throughput

0.628

High

285445

EED
Polycomb protein EED

1

17

High-throughput

0.618

High

519555

MYBB
Myb-related protein B

1

7

High-throughput

0.618

High

591821

H2AX
Histone H2AX

1

18

High-throughput

0.618

High

851655

GATA4
Transcription factor GATA-4

1

20

High-throughput

0.618

High

1017173

H33
Histone H3.3

1

20

High-throughput

0.618

High

1086811

BPTF
Nucleosome-remodeling factor subunit BPTF

1

20

High-throughput

0.618

High

1401044

PHF12
PHD finger protein 12

1

20

High-throughput

0.618

High

1406456

LYST
Lysosomal-trafficking regulator

1

7

High-throughput

0.618

High

1413353

RCOR3
REST corepressor 3

1

13

High-throughput

0.618

High

1413357

KDM5B
Lysine-specific demethylase 5B

1

8

Small-scale

0.618

High

1413362

RCOR1
REST corepressor 1

1

13

High-throughput

0.618

High

1413369

MTF2
Metal-response element-binding transcription factor 2

1

9

High-throughput

0.618

High

487696

PARP1
Poly [ADP-ribose] polymerase 1

2

8

High-throughput

0.614

High

71467

P20L1
PHD finger protein 20-like protein 1

2

4

High-throughput

0.611

High

1396116

Z512B
Zinc finger protein 512B

2

8

High-throughput

0.611

High

1413338

BC11B
B-cell lymphoma/leukemia 11B

2

6

High-throughput

0.611

High

1309571

F219A
Protein FAM219A

3

2

High-throughput

0.609

High

1371924

STMN2
Stathmin-2

2

2

High-throughput

0.601

High

1029742

FOXK2
Forkhead box protein K2

1

17

Small-scale

0.586

High

260386

BRD4
Bromodomain-containing protein 4

2

19

High-throughput

0.584

High

1137494

SUZ12
Polycomb protein SUZ12

2

4

High-throughput

0.584

High

1155715

EZH2
Histone-lysine N-methyltransferase EZH2

2

17

High-throughput

0.584

High

1396295

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

14

Small-scale

0.579

High

299490

CDKA2
Cyclin-dependent kinase 2-associated protein 2

2

8

Small-scale

0.571

High

396838

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

832791

BCL6
B-cell lymphoma 6 protein

1

4

Small-scale

0.561

High

1258266

UBP43
Ubiquitin carboxyl-terminal hydrolase 43

1

4

Small-scale

0.561

High

1238071

CGB2
Choriogonadotropin subunit beta variant 2

2

1

High-throughput

0.552

High

170321

AURKA
Aurora kinase A

1

4

High-throughput

0.541

High

294886

BCAR3
Breast cancer anti-estrogen resistance protein 3

1

3

High-throughput

0.541

High

336763

BAG4
BAG family molecular chaperone regulator 4

1

2

High-throughput

0.541

High

465631

IGF1R
Insulin-like growth factor 1 receptor

1

5

High-throughput

0.541

High

641248

FGFR2
Fibroblast growth factor receptor 2

1

6

High-throughput

0.541

High

693359

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

6

High-throughput

0.541

High

728409

AKT1
RAC-alpha serine/threonine-protein kinase

1

1

High-throughput

0.541

High

842988

CDN2C
Cyclin-dependent kinase 4 inhibitor C

1

11

High-throughput

0.541

High

1047715

NOTC2
Neurogenic locus notch homolog protein 2

1

5

High-throughput

0.541

High

1102244

ATM
Serine-protein kinase ATM

1

5

High-throughput

0.541

High

1115969

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

6

High-throughput

0.541

High

179076

IMA6
Importin subunit alpha-6

1

14

High-throughput

0.536

High

239187

ZNRD2
Protein ZNRD2

1

1

High-throughput

0.536

High

442799

RB
Retinoblastoma-associated protein

1

1

High-throughput

0.536

High

872692

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.536

High

1065400

SSRP1
FACT complex subunit SSRP1

1

20

High-throughput

0.536

High

1099767

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

3

High-throughput

0.536

High

1165248

ZN827
Zinc finger protein 827

1

8

Small-scale

0.536

High

1213140

BEND3
BEN domain-containing protein 3

1

2

High-throughput

0.536

High

1340863

GA2L2
GAS2-like protein 2

1

2

High-throughput

0.536

High

1340904

MB3L2
Methyl-CpG-binding domain protein 3-like 2

1

16

High-throughput

0.536

High

1367900

THRSP
Thyroid hormone-inducible hepatic protein

1

1

High-throughput

0.536

High

1383833

EFMT3
EEF1A lysine methyltransferase 3

1

1

High-throughput

0.536

High

1411088

BUD13
BUD13 homolog

1

2

High-throughput

0.536

High

1413347

SALL1
Sal-like protein 1

1

11

High-throughput

0.536

High

1413361

SALL4
Sal-like protein 4

1

11

High-throughput

0.536

High

376902

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.518

High

1407449

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.518

High

1133633

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.515

High

1337291

ACRBP
Acrosin-binding protein

1

0

High-throughput

0.513

High

1413368

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.513

High

1042918

ERCC6
DNA excision repair protein ERCC-6

1

20

High-throughput

0.501

High

1384565

NACC2
Nucleus accumbens-associated protein 2

1

20

Small-scale

0.501

High

249192

DSCAM
Cell adhesion molecule DSCAM

1

2

High-throughput

0.494

High

648648

FGFR4
Fibroblast growth factor receptor 4

1

6

High-throughput

0.494

High

187785

EIF3D
Eukaryotic translation initiation factor 3 subunit D

1

1

High-throughput

0.489

High

1413364

FZR1
Fizzy-related protein homolog

1

14

High-throughput

0.481

High

122843

KIF2A
Kinesin-like protein KIF2A

1

4

High-throughput

0.479

High

143225

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

157796

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.479

High

168317

HAT1
Histone acetyltransferase type B catalytic subunit

1

2

High-throughput

0.479

High

238600

RAD21
Double-strand-break repair protein rad21 homolog

1

1

Small-scale

0.479

High

242761

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

243722

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

20

High-throughput

0.479

High

274372

SIN3B
Paired amphipathic helix protein Sin3b

1

11

High-throughput

0.479

High

282299

SAP30
Histone deacetylase complex subunit SAP30

1

5

High-throughput

0.479

High

430301

JUN
Transcription factor Jun

1

12

Small-scale

0.479

High

474249

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

520338

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

630020

BTF3
Transcription factor BTF3

1

2

High-throughput

0.479

High

636139

CD11B
Cyclin-dependent kinase 11B

1

7

High-throughput

0.479

High

674307

BRD2
Bromodomain-containing protein 2

1

20

High-throughput

0.479

High

703370

SMCA1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1

1

20

High-throughput

0.479

High

776121

SOX5
Transcription factor SOX-5

1

20

High-throughput

0.479

High

776240

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.479

High

881594

CDK8
Cyclin-dependent kinase 8

1

7

High-throughput

0.479

High

887185

CEBPA
CCAAT/enhancer-binding protein alpha

1

13

High-throughput

0.479

High

892724

DNLI4
DNA ligase 4

1

1

High-throughput

0.479

High

897380

CDK7
Cyclin-dependent kinase 7

1

3

High-throughput

0.479

High

944730

KLF3
Krueppel-like factor 3

1

20

High-throughput

0.479

High

983956

RBX1
E3 ubiquitin-protein ligase RBX1

1

2

Small-scale

0.479

High

1032040

TFAP4
Transcription factor AP-4

1

2

Small-scale

0.479

High

1054782

SUH
Recombining binding protein suppressor of hairless

1

3

High-throughput

0.479

High

1087982

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1094725

CAF1A
Chromatin assembly factor 1 subunit A

1

5

High-throughput

0.479

High

1094803

CAF1B
Chromatin assembly factor 1 subunit B

1

11

High-throughput

0.479

High

1114159

CUL3
Cullin-3

1

8

High-throughput

0.479

High

1115392

CUL4B
Cullin-4B

1

8

Small-scale

0.479

High

1135273

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

20

High-throughput

0.479

High

1140775

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.479

High

1141282

BRD3
Bromodomain-containing protein 3

1

20

High-throughput

0.479

High

1157897

DDB1
DNA damage-binding protein 1

1

4

Small-scale

0.479

High

1195591

ARI4B
AT-rich interactive domain-containing protein 4B

1

14

High-throughput

0.479

High

1198002

LIN52
Protein lin-52 homolog

1

2

High-throughput

0.479

High

1208636

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

6

High-throughput

0.479

High

1216625

LIN9
Protein lin-9 homolog

1

2

High-throughput

0.479

High

1271825

MEPCE
7SK snRNA methylphosphate capping enzyme

1

2

High-throughput

0.479

High

1276721

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.479

High

1312686

BAP18
BPTF-associated chromatin complex component 1

1

2

High-throughput

0.479

High

1328933

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

5

High-throughput

0.479

High

1334848

SERB1
SERPINE1 mRNA-binding protein 1

1

2

High-throughput

0.479

High

1335457

HJURP
Holliday junction recognition protein

1

2

High-throughput

0.479

High

1357123

ZN296
Zinc finger protein 296

1

7

High-throughput

0.479

High

1357146

GATD1
GATA zinc finger domain-containing protein 1

1

2

High-throughput

0.479

High

1359063

FOG2
Zinc finger protein ZFPM2

1

12

Small-scale

0.479

High

1367148

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1392564

LIN37
Protein lin-37 homolog

1

2

High-throughput

0.479

High

1398766

PWP2A
PWWP domain-containing protein 2A

1

6

High-throughput

0.479

High

1401373

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1403008

SIN3A
Paired amphipathic helix protein Sin3a

1

11

High-throughput

0.479

High

1413337

DPY30
Protein dpy-30 homolog

1

3

High-throughput

0.479

High

1413339

SP130
Histone deacetylase complex subunit SAP130

1

10

High-throughput

0.479

High

1413340

BC11A
BCL11 transcription factor A

1

6

High-throughput

0.479

High

1413341

SMRCD
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1

1

20

High-throughput

0.479

High

1413342

PKHA4
Pleckstrin homology domain-containing family A member 4

1

9

High-throughput

0.479

High

1413343

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

1

6

High-throughput

0.479

High

1413344

NANOG
Homeobox protein NANOG

1

20

High-throughput

0.479

High

1413345

HM20A
High mobility group protein 20A

1

20

High-throughput

0.479

High

1413346

ANLN
Anillin

1

1

High-throughput

0.479

High

1413349

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

3

High-throughput

0.479

High

1413351

TLS1
Splicing factor C9orf78

1

4

High-throughput

0.479

High

1413352

HM20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

1

20

High-throughput

0.479

High

1413356

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1413358

TCF20
Transcription factor 20

1

9

High-throughput

0.479

High

1413365

CD11A
Cyclin-dependent kinase 11A

1

7

High-throughput

0.479

High

1413370

KLF12
Krueppel-like factor 12

1

18

High-throughput

0.479

High

245527

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

0

High-throughput

0.458

High

397978

ANGI
Angiogenin

1

2

High-throughput

0.445

High

911082

IMA1
Importin subunit alpha-1

1

14

High-throughput

0.445

High

1093571

TRDN
Triadin

1

1

Small-scale

0.445

High

1195490

PLCH1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1

1

1

Small-scale

0.445

High

1323396

FXL14
F-box/LRR-repeat protein 14

1

1

Small-scale

0.445

High

1404355

CDC5L
Cell division cycle 5-like protein

1

7

High-throughput

0.445

High

1413350

BCLF1
Bcl-2-associated transcription factor 1

1

1

Small-scale

0.445

High

1413367

TR150
Thyroid hormone receptor-associated protein 3

1

3

Small-scale

0.445

High

556314

CADH1
Cadherin-1

1

0

High-throughput

0.438

High

1130661

GSE1
Genetic suppressor element 1

1

2

High-throughput

0.437

High

1280914

CNTRL
Centriolin

1

5

High-throughput

0.437

High

1308372

CCD71
Coiled-coil domain-containing protein 71

1

2

Small-scale

0.437

High

1413359

HMGX4
HMG domain-containing protein 4

1

20

High-throughput

0.437

High

457659

TBB5
Tubulin beta chain

1

0

Small-scale

0.426

High

1247828

PADI6
Inactive protein-arginine deiminase type-6

1

0

Small-scale

0.426

High

276857

VATG1
V-type proton ATPase subunit G 1

1

0

High-throughput

0.249

Low

1234211

SN12L
Schlafen family member 12-like

1

0

High-throughput

0.249

Low

1413348

RM22
Large ribosomal subunit protein uL22m

1

0

High-throughput

0.249

Low

289810

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025