HitPredict

Interactor 1: PCNT (O95613)
Pericentrin (Kendrin) (Pericentrin-B)
Gene: PCNT

Interactor 2: AKAP6 (Q13023)
A-kinase anchor protein 6 (AKAP-6) (A-kinase anchor protein 100 kDa) (AKAP 100) (Protein kinase A-anchoring protein 6) (PRKA6) (mAKAP)
Gene: AKAP6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	35914814
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0060090 - molecular adaptor activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3336 Hs			1 2319
+	Hs
		317288 PCNT_HUMAN (1-3336): 0: 718: 100.00		CEP68_HUMAN (384-901): 2.44e-90: 314: 18.25
+	Hs
		317246 PCNT_HUMAN (1-3336): 0: 718: 100.00		SPTN1_HUMAN (913-1371): 1.2e-24: 115: 12.58
+	Hs
		164543 PCNT_HUMAN (1-3336): 0: 718: 100.00		SPTN2_HUMAN (614-1317): 3.95e-23: 110: 10.03
+	Hs
		317230 PCNT_HUMAN (1-3336): 0: 718: 100.00		SPTB2_HUMAN (620-1335): 3.36e-22: 107: 8.79
+	Hs
		317231 PCNT_HUMAN (1-3336): 0: 718: 100.00		DYST_HUMAN (268-1371): 1.25e-12: 76.2: 11.00
+	Hs
		317377 PCNT_HUMAN (1-3336): 0: 718: 100.00		MACF1_HUMAN (492-1238): 6.54e-11: 70.8: 10.98
+	Hs
		317303 PCNT_HUMAN (1-3336): 0: 718: 100.00		SYNE1_HUMAN (723-1252): 8.62e-11: 70.3: 12.82
+	Hs
		969584 CENPE_HUMAN (1328-3305): 2.89e-65: 250: 10.28		SPTN1_HUMAN (913-1371): 1.2e-24: 115: 12.58
+	Hs
		724994 CP250_HUMAN (1630-3336): 3.41e-53: 210: 10.43		MYH9_HUMAN (877-1373): 1.07e-19: 99.3: 10.37
+	Hs
		974137 CP250_HUMAN (1630-3336): 3.41e-53: 210: 10.43		DYST_HUMAN (268-1371): 1.25e-12: 76.2: 11.00
+	Hs
		522612 MYH7_HUMAN (2483-3316): 1.1e-33: 146: 12.07		SPTN1_HUMAN (913-1371): 1.2e-24: 115: 12.58
+	Dm
		527099 LVA_DROME (1967-3211): 1.36e-32: 142: 10.43		SPTCA_DROME (918-1371): 7.48e-26: 119: 12.06
+	Mm
		513821 PLEC_MOUSE (2-1335): 1.57e-39: 165: 10.63		DMD_MOUSE (724-1259): 3.99e-16: 87.6: 12.09
+	Hs
		724687 MYH10_HUMAN (2428-3327): 1.51e-34: 149: 10.93		MYH9_HUMAN (877-1373): 1.07e-19: 99.3: 10.37
+	Hs
		166696 CE290_HUMAN (1764-3201): 5.48e-34: 147: 10.55		DYST_HUMAN (268-1371): 1.25e-12: 76.2: 11.00
+	Hs
		1061289 NUMA1_HUMAN (43-1227): 1.53e-33: 145: 10.92		MACF1_HUMAN (492-1238): 6.54e-11: 70.8: 10.98
+	Hs
		164575 MYH9_HUMAN (2690-3313): 1.18e-18: 96.7: 9.89		SPTN2_HUMAN (614-1317): 3.95e-23: 110: 10.03
+	Hs
		724781 MYH9_HUMAN (2690-3313): 1.18e-18: 96.7: 9.89		SPTB2_HUMAN (620-1335): 3.36e-22: 107: 8.79
+	Hs
		724686 MYH9_HUMAN (2690-3313): 1.18e-18: 96.7: 9.89		MYH9_HUMAN (877-1373): 1.07e-19: 99.3: 10.37
+	Hs
		110636 MYH9_HUMAN (2690-3313): 1.18e-18: 96.7: 9.89		H3BPE1_HUMAN (492-1238): 3.96e-11: 71.1: 10.98