HitPredict

Interactor 1: BRD1 (O95696)
Bromodomain-containing protein 1 (BR140-like protein) (Bromodomain and PHD finger-containing protein 2)
Gene: BRD1

Interactor 2: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	27142060, 28977666
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Bromodomain~PHD, PHD~zf-HC5HC2H_2
Common GO terms	GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0042393 - histone binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1058 Hs			1 1912
+	Hs
		319179 BRD1_HUMAN (1-1058): 0: 1027: 100.00		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		319278 BRD1_HUMAN (1-1058): 0: 1027: 100.00		CHD5_HUMAN (86-1909): 0: 1584: 71.18
+	Hs
		1059760 PHIP_HUMAN (348-939): 3.6e-54: 209: 13.41		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		299056 PHF14_HUMAN (173-572): 2.71e-54: 207: 17.83		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1059704 PB1_HUMAN (351-673): 1.92e-28: 126: 15.92		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		299054 PHF14_HUMAN (173-572): 2.71e-54: 207: 17.83		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1255033 PHIP_HUMAN (348-939): 3.6e-54: 209: 13.41		CHD5_HUMAN (86-1909): 0: 1584: 71.18
+	Hs
		256980 KDM4A_HUMAN (224-363): 2.46e-50: 195: 41.67		CHD5_HUMAN (86-1909): 0: 1584: 71.18
+	Hs
		1018557 PB1_HUMAN (351-673): 1.92e-28: 126: 15.92		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		600135 TAF1_HUMAN (344-928): 1.64e-24: 113: 10.34		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Sc
		697456 NTO1_YEAST (58-613): 9.77e-113: 368: 25.47		CHD1_YEAST (515-1383): 0: 777: 35.17
+	Hs
		1342808 BRD7_HUMAN (487-954): 2.63e-53: 200: 18.15		CHD7_HUMAN (3-1678): 0: 805: 23.02
+	Hs
		229448 PHIP_HUMAN (348-939): 3.6e-54: 209: 13.41		SMCA5_HUMAN (578-1624): 0: 791: 26.01
+	Hs
		1317720 NSD3_HUMAN (46-605): 1.83e-50: 196: 11.47		CHD8_HUMAN (489-1678): 0: 752: 28.31
+	Hs
		151436 PHIP_HUMAN (348-939): 3.6e-54: 209: 13.41		CHD1_HUMAN (491-1733): 0: 734: 27.99
+	Hs
		1199209 PB1_HUMAN (351-673): 1.92e-28: 126: 15.92		CHD7_HUMAN (3-1678): 0: 805: 23.02
+	Hs
		1199201 PB1_HUMAN (351-673): 1.92e-28: 126: 15.92		CHD8_HUMAN (489-1678): 0: 752: 28.31