HitPredict

Interactor 1: BRD1 (O95696)
Bromodomain-containing protein 1 (BR140-like protein) (Bromodomain and PHD finger-containing protein 2)
Gene: BRD1

Interactor 2: ING4 (Q9UNL4)
Inhibitor of growth protein 4 (p29ING4)
Gene: ING4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	1.00	0.950

Property	Details
Experiments	26496610, 27142060, 31753913, 24981860, 33961781, 37071682
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EPL1~ING
Common GO terms	GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0006355 - regulation of DNA-templated transcription GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1058 Hs			1 249
+	Hs
		319285 BRD1_HUMAN (1-1058): 0: 1027: 100.00		ING5_HUMAN (1-249): 6.7e-86: 257: 67.87
+	Hs
		876727 BRPF1_HUMAN (2-1058): 0: 834: 50.04		ING4_HUMAN (1-249): 7.49e-98: 287: 100.00
+	Hs
		876708 BRPF1_HUMAN (2-1058): 0: 834: 50.04		ING5_HUMAN (1-249): 6.7e-86: 257: 67.87
+	Hs
		876726 BRPF1_HUMAN (2-1058): 0: 834: 50.04		ZMYD8_HUMAN (125-244): 1.26e-19: 89.6: 22.39
+	Hs
		1152696 JADE1_HUMAN (110-894): 5.55e-121: 393: 22.78		ING4_HUMAN (1-249): 7.49e-98: 287: 100.00
+	Hs
		1152683 JADE1_HUMAN (110-894): 5.55e-121: 393: 22.78		ING5_HUMAN (1-249): 6.7e-86: 257: 67.87
+	Hs
		1268057 JADE3_HUMAN (110-590): 6.17e-90: 308: 29.03		ING4_HUMAN (1-249): 7.49e-98: 287: 100.00
+	Hs
		1343287 JADE2_HUMAN (110-875): 6.63e-87: 299: 23.23		ING4_HUMAN (1-249): 7.49e-98: 287: 100.00
+	Hs
		2717 A0A0C4DFT8_HUMAN (110-875): 6.12e-87: 299: 23.33		ING4_HUMAN (1-249): 7.49e-98: 287: 100.00
+	Hs
		1264466 JADE3_HUMAN (110-590): 6.17e-90: 308: 29.03		ING5_HUMAN (1-249): 6.7e-86: 257: 67.87
+	Hs
		1264487 JADE2_HUMAN (110-875): 6.63e-87: 299: 23.23		ING5_HUMAN (1-249): 6.7e-86: 257: 67.87
+	Hs
		2713 A0A0C4DFT8_HUMAN (110-875): 6.12e-87: 299: 23.33		ING5_HUMAN (1-249): 6.7e-86: 257: 67.87
+	Hs
		1356827 BRPF3_HUMAN (667-1055): 2.04e-69: 255: 34.78		ING4_HUMAN (1-249): 7.49e-98: 287: 100.00
+	Sc
		995740 NTO1_YEAST (58-613): 9.77e-113: 368: 25.47		YNG1_YEAST (10-245): 1.11e-42: 146: 22.88
+	Hs
		1264497 BRPF3_HUMAN (667-1055): 2.04e-69: 255: 34.78		ING5_HUMAN (1-249): 6.7e-86: 257: 67.87
+	Dm
		1177410 BRDH_DROME (708-1046): 8.86e-57: 216: 27.35		ING5_DROME (1-249): 1.49e-73: 227: 46.34
+	Hs
		1268053 JADE3_HUMAN (110-590): 6.17e-90: 308: 29.03		ING3_HUMAN (180-249): 2.39e-32: 123: 57.14
+	Hs
		1343284 JADE2_HUMAN (110-875): 6.63e-87: 299: 23.23		ING3_HUMAN (180-249): 2.39e-32: 123: 57.14
+	Hs
		1348038 BRPF3_HUMAN (667-1055): 2.04e-69: 255: 34.78		ING3_HUMAN (180-249): 2.39e-32: 123: 57.14
+	Hs
		1139022 PHIP_HUMAN (348-939): 3.6e-54: 209: 13.41		TAF3_HUMAN (112-244): 6.36e-23: 99.2: 22.15