Protein: CRTC2
CREB-regulated transcription coactivator 2 (Transducer of regulated cAMP response element-binding protein 2) (TORC-2) (Transducer of CREB protein 2)

Gene: CRTC2
Organism: Homo sapiens
Interactions: 63
UniProt ID: Q53ET0

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006094 - gluconeogenesis
GO:0008140 - cAMP response element binding protein binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

556883

CREB1
Cyclic AMP-responsive element-binding protein 1

2

4

High-throughput

0.783

High

683398

1433B
14-3-3 protein beta/alpha

7

20

Small-scale

0.747

High

646948

1433T
14-3-3 protein theta

7

20

Small-scale

0.745

High

904648

1433G
14-3-3 protein gamma

6

20

High-throughput

0.737

High

927110

1433Z
14-3-3 protein zeta/delta

4

20

High-throughput

0.704

High

982079

1433F
14-3-3 protein eta

4

20

High-throughput

0.697

High

909630

1433E
14-3-3 protein epsilon

3

7

High-throughput

0.675

High

1120147

SIK2
Serine/threonine-protein kinase SIK2

2

6

Small-scale

0.629

High

819157

PP2BC
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

2

11

High-throughput

0.628

High

1120144

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

1

High-throughput

0.628

High

579346

ATF6A
Cyclic AMP-dependent transcription factor ATF-6 alpha

1

9

Small-scale

0.618

High

1102727

CCD57
Coiled-coil domain-containing protein 57

2

5

High-throughput

0.606

High

1120156

CDC23
Cell division cycle protein 23 homolog

2

2

High-throughput

0.606

High

1120158

SUFU
Suppressor of fused homolog

2

1

High-throughput

0.606

High

926738

CANB1
Calcineurin subunit B type 1

2

0

High-throughput

0.602

High

1069697

NONO
Non-POU domain-containing octamer-binding protein

1

3

Small-scale

0.561

High

557551

PP2BB
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

1

11

High-throughput

0.536

High

896908

ARP2
Actin-related protein 2

1

7

High-throughput

0.536

High

960828

CLH1
Clathrin heavy chain 1

1

4

High-throughput

0.536

High

1120148

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.536

High

1120151

GTSE1
G2 and S phase-expressed protein 1

1

4

High-throughput

0.536

High

519006

PIP
Prolactin-inducible protein

1

0

High-throughput

0.513

High

808152

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

8

High-throughput

0.501

High

883226

SIK1
Serine/threonine-protein kinase SIK1

1

6

Small-scale

0.501

High

1025144

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

4

Small-scale

0.501

High

1120159

SIK3
Serine/threonine-protein kinase SIK3

1

6

Small-scale

0.501

High

1120161

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

8

High-throughput

0.501

High

162816

XPO1
Exportin-1

1

7

High-throughput

0.479

High

352122

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

1

High-throughput

0.479

High

386853

P53
Cellular tumor antigen p53

1

11

High-throughput

0.479

High

934833

H31
Histone H3.1

1

20

Small-scale

0.479

High

962812

MDM2
E3 ubiquitin-protein ligase Mdm2

1

1

Small-scale

0.479

High

980766

TLE3
Transducin-like enhancer protein 3

1

10

High-throughput

0.479

High

994087

PP2BA
Protein phosphatase 3 catalytic subunit alpha

1

12

Small-scale

0.479

High

995377

LG3BP
Galectin-3-binding protein

1

3

High-throughput

0.479

High

998797

EP300
Histone acetyltransferase p300

1

18

Small-scale

0.479

High

1120135

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

8

High-throughput

0.479

High

1120136

KSR1
Kinase suppressor of Ras 1

1

7

High-throughput

0.479

High

1120139

NUP35
Nucleoporin NUP35

1

4

High-throughput

0.479

High

1120140

NEDD1
Protein NEDD1

1

6

High-throughput

0.479

High

1120141

COP1
E3 ubiquitin-protein ligase COP1

1

14

Small-scale

0.479

High

1120142

HDAC2
Histone deacetylase 2

1

13

High-throughput

0.479

High

1120143

CBP
CREB-binding protein

1

16

Small-scale

0.479

High

1120145

CP250
Centrosome-associated protein CEP250

1

4

High-throughput

0.479

High

1120146

DDA1
DET1- and DDB1-associated protein 1

1

1

High-throughput

0.479

High

1120150

KI13B
Kinesin-like protein KIF13B

1

6

High-throughput

0.479

High

1120154

HECW2
E3 ubiquitin-protein ligase HECW2

1

8

High-throughput

0.479

High

1120155

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

1120157

ZBT21
Zinc finger and BTB domain-containing protein 21

1

5

High-throughput

0.479

High

1120160

CBY1
Protein chibby homolog 1

1

2

High-throughput

0.479

High

1120162

TRAF6
TNF receptor-associated factor 6

1

7

Small-scale

0.479

High

758250

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.458

High

1120133

SMAG2
Protein Smaug homolog 2

1

0

High-throughput

0.458

High

129977

MEIS1
Homeobox protein Meis1

1

4

Small-scale

0.445

High

1056290

ITPR1
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1

1

1

Small-scale

0.437

High

1120149

RC3H2
Roquin-2

1

9

High-throughput

0.437

High

1120153

CING
Cingulin

1

1

High-throughput

0.437

High

1120163

KCTD3
BTB/POZ domain-containing protein KCTD3

1

3

High-throughput

0.437

High

1120134

TMIG1
Transmembrane and immunoglobulin domain-containing protein 1

1

0

Small-scale

0.426

High

1120137

ATPF2
ATP synthase mitochondrial F1 complex assembly factor 2

2

0

High-throughput

0.316

High

1120138

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

1

0

High-throughput

0.279

Low

264319

GGYF1
GRB10-interacting GYF protein 1

1

0

High-throughput

0.249

Low

1120152

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024