HitPredict

Interactor 1: CXL14 (O95715)
C-X-C motif chemokine 14 (Chemokine BRAK) (MIP-2G) (Small-inducible cytokine B14)
Gene: CXCL14

Interactor 2: CCL26 (Q9Y258)
C-C motif chemokine 26 (CC chemokine IMAC) (Eotaxin-3) (Macrophage inflammatory protein 4-alpha) (MIP-4-alpha) (Small-inducible cytokine A26) (Thymic stroma chemokine-1) (TSC-1)
Gene: CCL26

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.692

Property	Details
Experiments	28381538
Identification Methods	pull down, filter binding
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	IL8~IL8
Common GO terms	GO:0005615 - extracellular space GO:0006935 - chemotaxis GO:0007165 - signal transduction GO:0007267 - cell-cell signaling GO:0008009 - chemokine activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 111 Hs			1 94
+	Hs
		320109 CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00		CCL13_HUMAN (2-91): 2.05e-31: 107: 33.70
+	Hs
		320105 CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00		CCL17_HUMAN (1-89): 5.64e-28: 98.9: 29.21
+	Hs
		320085 CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00		CCL5_HUMAN (14-90): 3.98e-25: 91.6: 37.66
+	Hs
		320095 CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00		CCL11_HUMAN (16-92): 6.19e-25: 91.2: 34.62
+	Hs
		320092 CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00		XCL1_HUMAN (6-92): 5.59e-21: 81.5: 29.89
+	Hs
		134280 CXL14_HUMAN (1-111): 2.98e-72: 211: 100.00		CCL21_HUMAN (25-91): 5.26e-17: 71.9: 28.17