HitPredict

Interactor 1: CRTAM (O95727)
Cytotoxic and regulatory T-cell molecule (Class-I MHC-restricted T-cell-associated molecule) (CD antigen CD355)
Gene: CRTAM

Interactor 2: CRTAM (O95727)
Cytotoxic and regulatory T-cell molecule (Class-I MHC-restricted T-cell-associated molecule) (CD antigen CD355)
Gene: CRTAM

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.820

The method score is based on:

Property Details
Experiments 23583034, 23871486
Identification Methods molecular sieving, cosedimentation in solution, x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains C2-set_2~C2-set_2, C2-set_2~V-set, V-set~V-set
Common GO terms GO:0001768 - establishment of T cell polarity
GO:0001772 - immunological synapse
GO:0001819 - positive regulation of cytokine production
GO:0002250 - adaptive immune response
GO:0002355 - detection of tumor cell
and 13 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 393
Hs

1 393
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+ Dm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024