HitPredict

Interactor 1: PTBP3 (O95758)
Polypyrimidine tract-binding protein 3 (Regulator of differentiation 1) (Rod1)
Gene: PTBP3

Interactor 2: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	23403292, 33731348
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 552 Hs			1 595
+	Hs
		369019 PTBP1_HUMAN (1-552): 1.59e-114: 352: 75.27		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		370797 RBM19_HUMAN (44-549): 3.53e-79: 269: 17.64		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		370088 HNRLL_HUMAN (18-551): 4.91e-60: 209: 22.69		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		321148 PTBP3_HUMAN (1-552): 2.33e-115: 354: 100.00		ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88
+	Hs
		369534 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		368886 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		611374 PTBP1_HUMAN (1-552): 1.59e-114: 352: 75.27		NR4A1_HUMAN (64-549): 2.81e-105: 331: 24.54
+	Hs
		1270016 RBM19_HUMAN (44-549): 3.53e-79: 269: 17.64		ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88
+	Hs
		1261872 HNRLL_HUMAN (18-551): 4.91e-60: 209: 22.69		ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88
+	Hs
		1031409 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88
+	Hs
		540897 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		NR4A1_HUMAN (64-549): 2.81e-105: 331: 24.54
+	Hs
		487896 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		RARA_HUMAN (81-545): 1.35e-102: 320: 22.37
+	Hs
		782537 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		HNF4A_HUMAN (146-592): 2.13e-118: 361: 20.58
+	Hs
		487148 PTBP1_HUMAN (1-552): 1.59e-114: 352: 75.27		ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16
+	Hs
		611434 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		NR4A1_HUMAN (64-549): 2.81e-105: 331: 24.54
+	Hs
		516359 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		NR4A1_HUMAN (64-549): 2.81e-105: 331: 24.54
+	Mm
		509289 PABP1_MOUSE (4-266): 2.93e-36: 145: 12.45		RARA_MOUSE (81-545): 8.36e-104: 323: 22.37
+	Dm
		1212673 Q8IHH3_DROME (282-550): 2.09e-64: 217: 25.61		Q8WS79_DROME (183-488): 2.28e-50: 183: 35.37
+	Hs
		487097 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16
+	Hs
		487081 PABP1_HUMAN (4-266): 3.64e-36: 144: 12.45		ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16