HitPredict

Interactor 1: PTBP3 (O95758)
Polypyrimidine tract-binding protein 3 (Regulator of differentiation 1) (Rod1)
Gene: PTBP3

Interactor 2: PUF60 (Q9UHX1)
Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (FUSE-binding protein-interacting repressor) (FBP-interacting repressor) (Ro-binding protein 1) (RoBP1) (Siah-binding protein 1) (Siah-BP1)
Gene: PUF60

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	22575643
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	RRM_1~RRM_5
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 552 Hs			1 559
+	Hs
		1355614 PTBP2_HUMAN (1-552): 3.79e-96: 304: 66.00		PUF60_HUMAN (1-559): 2.1e-103: 324: 100.00
+	Hs
		321076 PTBP3_HUMAN (1-552): 2.33e-115: 354: 100.00		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		643504 PTBP1_HUMAN (1-552): 1.59e-114: 352: 75.27		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		541188 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		PUF60_HUMAN (1-559): 2.1e-103: 324: 100.00
+	Hs
		321063 PTBP3_HUMAN (1-552): 2.33e-115: 354: 100.00		ELAV2_HUMAN (223-553): 1.56e-45: 165: 14.80
+	Hs
		321161 PTBP3_HUMAN (1-552): 2.33e-115: 354: 100.00		PABP5_HUMAN (133-308): 3.43e-45: 165: 23.86
+	Dm
		562816 ELAV_DROME (29-434): 1.4e-56: 198: 20.53		PUF68_DROME (57-559): 1.81e-97: 311: 47.24
+	Hs
		541010 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		321151 PTBP3_HUMAN (1-552): 2.33e-115: 354: 100.00		CELF1_HUMAN (98-214): 1.29e-17: 87.5: 26.50
+	Hs
		311330 PTBP3_HUMAN (1-552): 2.33e-115: 354: 100.00		CELF2_HUMAN (116-203): 3.74e-17: 86.5: 31.82
+	Hs
		643557 PTBP1_HUMAN (1-552): 1.59e-114: 352: 75.27		CELF1_HUMAN (98-214): 1.29e-17: 87.5: 26.50
+	Hs
		1288653 RBM19_HUMAN (44-549): 3.53e-79: 269: 17.64		PABP5_HUMAN (133-308): 3.43e-45: 165: 23.86
+	Hs
		1272124 PTBP2_HUMAN (1-552): 3.79e-96: 304: 66.00		CELF1_HUMAN (98-214): 1.29e-17: 87.5: 26.50
+	Hs
		1031328 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		540986 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		ELAV2_HUMAN (223-553): 1.56e-45: 165: 14.80
+	Hs
		1020249 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		ELAV2_HUMAN (223-553): 1.56e-45: 165: 14.80
+	Hs
		541087 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		CELF1_HUMAN (98-214): 1.29e-17: 87.5: 26.50
+	Hs
		516346 HNRPL_HUMAN (47-551): 6.01e-60: 210: 24.24		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Hs
		474021 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		PAB4L_HUMAN (479-559): 3.69e-14: 76.1: 20.99
+	Hs
		516495 PABP4_HUMAN (4-266): 3.85e-37: 147: 13.55		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64