HitPredict

Interactor 1: TBCD8 (O95759)
TBC1 domain family member 8 (AD 3) (Vascular Rab-GAP/TBC-containing protein)
Gene: TBC1D8

Interactor 2: RAB4A (P20338)
Ras-related protein Rab-4A (EC 3.6.5.2)
Gene: RAB4A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.80	0.675

Property	Details
Experiments	34079125, 37232246
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1140 Hs			1 218
+	Hs
		321281 TBCD8_HUMAN (1-1140): 0: 1098: 100.00		RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33
+	Hs
		895137 TBCD9_HUMAN (1-1101): 0: 1007: 47.73		RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92
+	Dm
		1197047 EVI5_DROME (400-1139): 2.38e-119: 389: 15.83		Q86BK8_DROME (3-218): 6.99e-93: 273: 56.94
+	Hs
		1079952 EVI5L_HUMAN (398-1080): 1.07e-117: 385: 16.16		RB11B_HUMAN (3-217): 1.16e-83: 249: 43.26
+	Hs
		914275 EVI5L_HUMAN (398-1080): 1.07e-117: 385: 16.16		RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33
+	Hs
		592076 RBGP1_HUMAN (323-981): 1.21e-94: 328: 17.18		RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00
+	Hs
		914482 RBGP1_HUMAN (323-981): 1.21e-94: 328: 17.18		RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33
+	Dm
		185716 EVI5_DROME (400-1139): 2.38e-119: 389: 15.83		O18335_DROME (5-185): 7.23e-54: 173: 50.55
+	Hs
		895106 TB10B_HUMAN (358-787): 1.63e-81: 286: 21.14		RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92
+	Os
		1130873 Q5SMT0_ORYSJ (266-743): 2.55e-81: 282: 15.91		Q6YY17_ORYSJ (9-197): 1.31e-91: 268: 55.03
+	Hs
		232698 TBCD4_HUMAN (367-884): 3.57e-82: 295: 18.10		RAB2B_HUMAN (10-218): 1.65e-82: 246: 51.87
+	Hs
		914176 TBCD1_HUMAN (367-843): 2.49e-80: 288: 17.04		RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33
+	Os
		772871 Q5SMT0_ORYSJ (266-743): 2.55e-81: 282: 15.91		RIC2_ORYSJ (1-217): 1.78e-82: 246: 38.99
+	Hs
		1079972 TBC14_HUMAN (366-772): 1.46e-79: 277: 17.74		RB11B_HUMAN (3-217): 1.16e-83: 249: 43.26
+	Hs
		914423 TBC14_HUMAN (366-772): 1.46e-79: 277: 17.74		RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33
+	Hs
		592065 TBD2B_HUMAN (479-727): 3.23e-30: 131: 33.20		RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00
+	Hs
		914465 TBD2B_HUMAN (479-727): 3.23e-30: 131: 33.20		RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33
+	Hs
		234370 EVI5_HUMAN (822-1139): 3.57e-20: 98.8: 11.11		RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33
+	Hs
		234378 EVI5_HUMAN (822-1139): 3.57e-20: 98.8: 11.11		RB11B_HUMAN (3-217): 1.16e-83: 249: 43.26
+	Sc
		750745 GYP3_YEAST (494-721): 1.38e-29: 127: 31.39		YPT31_YEAST (1-184): 1.2e-54: 175: 47.28