HitPredict

Interactor 1: TBCD8 (O95759)
TBC1 domain family member 8 (AD 3) (Vascular Rab-GAP/TBC-containing protein)
Gene: TBC1D8

Interactor 2: RND3 (P61587)
Rho-related GTP-binding protein RhoE (Protein MemB) (Rho family GTPase 3) (Rho-related GTP-binding protein Rho8) (Rnd3)
Gene: RND3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1140 Hs			1 244
+	Hs
		321278 TBCD8_HUMAN (1-1140): 0: 1098: 100.00		RND2_HUMAN (20-244): 3.9e-103: 300: 64.00
+	Hs
		321279 TBCD8_HUMAN (1-1140): 0: 1098: 100.00		CDC42_HUMAN (24-208): 1.29e-82: 246: 40.00
+	Hs
		915717 TB10B_HUMAN (358-787): 1.63e-81: 286: 21.14		RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84
+	Hs
		915938 TB10A_HUMAN (400-758): 3.31e-82: 279: 24.93		RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84
+	Hs
		232655 TBCD4_HUMAN (367-884): 3.57e-82: 295: 18.10		CDC42_HUMAN (24-208): 1.29e-82: 246: 40.00
+	Hs
		925323 TB10B_HUMAN (358-787): 1.63e-81: 286: 21.14		RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32
+	Hs
		892404 TB10B_HUMAN (358-787): 1.63e-81: 286: 21.14		RAC3_HUMAN (24-199): 1.42e-75: 229: 43.75
+	Os
		772871 Q5SMT0_ORYSJ (266-743): 2.55e-81: 282: 15.91		RIC2_ORYSJ (10-242): 1.63e-76: 232: 24.68
+	Hs
		894392 TBD2A_HUMAN (485-780): 1.16e-73: 265: 27.24		CDC42_HUMAN (24-208): 1.29e-82: 246: 40.00
+	Hs
		1117434 TB10B_HUMAN (358-787): 1.63e-81: 286: 21.14		RHOF_HUMAN (25-212): 1.18e-52: 171: 45.21
+	Hs
		564554 TB10B_HUMAN (358-787): 1.63e-81: 286: 21.14		RHOQ_HUMAN (25-212): 8.64e-51: 166: 42.02
+	Hs
		852679 TBD2B_HUMAN (479-727): 3.23e-30: 131: 33.20		RND2_HUMAN (20-244): 3.9e-103: 300: 64.00
+	Hs
		1269257 TBD2B_HUMAN (479-727): 3.23e-30: 131: 33.20		RND1_HUMAN (1-244): 1.22e-90: 268: 58.20
+	Hs
		916079 TBD2B_HUMAN (479-727): 3.23e-30: 131: 33.20		RHOB_HUMAN (22-200): 2.38e-90: 266: 50.84
+	Hs
		925738 TBD2B_HUMAN (479-727): 3.23e-30: 131: 33.20		RAC1_HUMAN (24-210): 3.03e-80: 240: 43.32
+	Ce
		975574 Q23419_CAEEL (488-731): 1.48e-31: 135: 31.64		RAC1_CAEEL (24-208): 1.83e-77: 233: 43.78
+	Hs
		892684 TBD2B_HUMAN (479-727): 3.23e-30: 131: 33.20		RAC3_HUMAN (24-199): 1.42e-75: 229: 43.75
+	Hs
		951462 TBD2B_HUMAN (479-727): 3.23e-30: 131: 33.20		RHOG_HUMAN (23-208): 1.85e-74: 226: 42.47
+	Mm
		925784 EVI5_MOUSE (833-1139): 1.74e-21: 103: 10.58		RAC1_MOUSE (24-210): 3.03e-80: 240: 43.32
+	Sc
		419713 GYP3_YEAST (494-721): 1.38e-29: 127: 31.39		RHO1_YEAST (21-202): 1.15e-62: 196: 51.35