HitPredict

Interactor 1: RIGI (O95786)
Antiviral innate immune response receptor RIG-I (ATP-dependent RNA helicase DDX58) (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (RNA sensor RIG-I) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)
Gene: RIGI

Interactor 2: UBE2K (P61086)
Ubiquitin-conjugating enzyme E2 K (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme K) (Huntingtin-interacting protein 2) (HIP-2) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-25 kDa) (Ubiquitin-conjugating enzyme E2(25K)) (Ubiquitin-conjugating enzyme E2-25K) (Ubiquitin-protein ligase)
Gene: UBE2K

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	17719635
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 925 Hs			1 200
+	Hs
		321878 RIGI_HUMAN (1-925): 0: 635: 100.00		UB2D1_HUMAN (4-154): 1.87e-75: 225: 39.74
+	Hs
		321884 RIGI_HUMAN (1-925): 0: 635: 100.00		UB2D2_HUMAN (4-154): 7.76e-75: 223: 41.06
+	Hs
		321880 RIGI_HUMAN (1-925): 0: 635: 100.00		UB2D3_HUMAN (4-154): 1.49e-73: 220: 39.74
+	Hs
		757509 IF4A3_HUMAN (238-609): 6.59e-19: 92.3: 13.17		UBE2A_HUMAN (1-151): 4.98e-67: 203: 30.46