HitPredict

Interactor 1: RIGI (O95786)
Antiviral innate immune response receptor RIG-I (ATP-dependent RNA helicase DDX58) (EC 3.6.4.13) (DEAD box protein 58) (RIG-I-like receptor 1) (RLR-1) (RNA sensor RIG-I) (Retinoic acid-inducible gene 1 protein) (RIG-1) (Retinoic acid-inducible gene I protein) (RIG-I)
Gene: RIGI

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 925 Hs			1 779
+	Hs
		1331645 DICER_HUMAN (220-773): 2.88e-93: 326: 21.46		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1183360 DDX46_HUMAN (89-872): 2.36e-83: 291: 12.00		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1271662 DDX17_HUMAN (410-831): 1.46e-49: 189: 11.75		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		571596 DDX5_HUMAN (459-798): 1.16e-47: 182: 14.05		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		181736 DDX3Y_HUMAN (380-774): 3.83e-45: 175: 13.70		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		134208 DDX3X_HUMAN (411-774): 1.03e-44: 174: 13.92		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1328083 DDX47_HUMAN (408-807): 8.54e-46: 173: 14.49		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1204698 DDX42_HUMAN (455-774): 2.26e-43: 172: 15.00		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1153459 DICER_HUMAN (220-773): 2.88e-93: 326: 21.46		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1153317 DDX17_HUMAN (410-831): 1.46e-49: 189: 11.75		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		571491 DDX5_HUMAN (459-798): 1.16e-47: 182: 14.05		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		134083 DDX3X_HUMAN (411-774): 1.03e-44: 174: 13.92		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1153276 DDX42_HUMAN (455-774): 2.26e-43: 172: 15.00		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1022418 DDX42_HUMAN (455-774): 2.26e-43: 172: 15.00		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		1133681 DDX42_HUMAN (455-774): 2.26e-43: 172: 15.00		RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18
+	Hs
		1231289 DDX17_HUMAN (410-831): 1.46e-49: 189: 11.75		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		571517 DDX5_HUMAN (459-798): 1.16e-47: 182: 14.05		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		181718 DDX3Y_HUMAN (380-774): 3.83e-45: 175: 13.70		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		134122 DDX3X_HUMAN (411-774): 1.03e-44: 174: 13.92		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		757653 IF4A3_HUMAN (238-609): 6.59e-19: 92.3: 13.17		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02