HitPredict

Interactor 1: STAU1 (O95793)
Double-stranded RNA-binding protein Staufen homolog 1
Gene: STAU1

Interactor 2: TOP2A (P11388)
DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme)
Gene: TOP2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	30948266, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 577 Hs			1 1531
+	Hs
		322503 STAU1_HUMAN (1-577): 0: 524: 100.00		TOP2B_HUMAN (14-1523): 0: 1644: 65.85
+	Hs
		508887 DSRAD_HUMAN (246-572): 7.91e-51: 191: 16.57		TOP2A_HUMAN (1-1531): 0: 1750: 100.00
+	Hs
		508939 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		TOP2A_HUMAN (1-1531): 0: 1750: 100.00
+	Hs
		877246 DSRAD_HUMAN (246-572): 7.91e-51: 191: 16.57		TOP2B_HUMAN (14-1523): 0: 1644: 65.85
+	Hs
		508971 ILF3_HUMAN (245-488): 2.36e-15: 81.6: 15.45		TOP2A_HUMAN (1-1531): 0: 1750: 100.00
+	Hs
		944748 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		TOP2B_HUMAN (14-1523): 0: 1644: 65.85