HitPredict

Interactor 1: STAU1 (O95793)
Double-stranded RNA-binding protein Staufen homolog 1
Gene: STAU1

Interactor 2: DHX58 (Q96C10)
ATP-dependent RNA helicase DHX58 (EC 3.6.4.13) (ATP-dependent helicase LGP2) (Protein D11Lgp2 homolog) (RIG-I-like receptor 3) (RLR-3) (RIG-I-like receptor LGP2) (RLR)
Gene: DHX58

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	21903422
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Helicase_C~dsrm
Common GO terms	GO:0003725 - double-stranded RNA binding GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 577 Hs			1 678
+	Hs
		323319 STAU1_HUMAN (1-577): 0: 524: 100.00		DICER_HUMAN (3-515): 7.66e-90: 309: 21.54
+	Hs
		322538 STAU1_HUMAN (1-577): 0: 524: 100.00		CHD3_HUMAN (2-588): 7.71e-78: 273: 12.95
+	Hs
		229267 STAU1_HUMAN (1-577): 0: 524: 100.00		SMCA5_HUMAN (2-611): 7.74e-78: 270: 12.38
+	Hs
		322219 STAU1_HUMAN (1-577): 0: 524: 100.00		SMCA1_HUMAN (3-611): 3.05e-74: 260: 12.31
+	Hs
		322641 STAU1_HUMAN (1-577): 0: 524: 100.00		CHD4_HUMAN (2-626): 2.02e-73: 260: 12.48
+	Hs
		323108 STAU1_HUMAN (1-577): 0: 524: 100.00		DDX24_HUMAN (3-557): 6.6e-57: 209: 14.35
+	Hs
		133809 STAU1_HUMAN (1-577): 0: 524: 100.00		DDX3X_HUMAN (146-516): 5.67e-56: 203: 16.67
+	Hs
		322951 STAU1_HUMAN (1-577): 0: 524: 100.00		DDX17_HUMAN (2-260): 1.9e-42: 165: 17.23
+	Hs
		322157 STAU1_HUMAN (1-577): 0: 524: 100.00		DDX5_HUMAN (2-255): 1.99e-37: 150: 15.21
+	Hs
		322273 STAU1_HUMAN (1-577): 0: 524: 100.00		IF4A3_HUMAN (2-345): 5e-28: 118: 8.96
+	Hs
		322997 STAU1_HUMAN (1-577): 0: 524: 100.00		DDX27_HUMAN (2-371): 4.82e-10: 64.9: 16.27
+	Hs
		1302246 STRBP_HUMAN (48-336): 1.3e-63: 223: 17.33		DICER_HUMAN (3-515): 7.66e-90: 309: 21.54
+	Hs
		877391 DSRAD_HUMAN (246-572): 7.91e-51: 191: 16.57		DICER_HUMAN (3-515): 7.66e-90: 309: 21.54
+	Hs
		1018651 STRBP_HUMAN (48-336): 1.3e-63: 223: 17.33		CHD3_HUMAN (2-588): 7.71e-78: 273: 12.95
+	Hs
		1059810 STRBP_HUMAN (48-336): 1.3e-63: 223: 17.33		CHD4_HUMAN (2-626): 2.02e-73: 260: 12.48
+	Hs
		877254 DSRAD_HUMAN (246-572): 7.91e-51: 191: 16.57		CHD3_HUMAN (2-588): 7.71e-78: 273: 12.95
+	Hs
		877324 DSRAD_HUMAN (246-572): 7.91e-51: 191: 16.57		CHD5_HUMAN (2-626): 3.23e-76: 269: 11.10
+	Hs
		877275 DSRAD_HUMAN (246-572): 7.91e-51: 191: 16.57		CHD4_HUMAN (2-626): 2.02e-73: 260: 12.48
+	At
		1108230 DCL1_ARATH (185-353): 2.77e-36: 147: 21.02		DCL2_ARATH (3-496): 9.09e-85: 293: 22.22
+	Dm
		1363205 LOQS_DROME (119-559): 5.84e-75: 247: 21.38		DCR1_DROME (3-244): 8.63e-11: 67.9: 17.48